Process for production of lasofoxifene or analogue thereof
    1.
    发明授权
    Process for production of lasofoxifene or analogue thereof 有权
    雷诺昔芬或其类似物的生产方法

    公开(公告)号:US08193394B2

    公开(公告)日:2012-06-05

    申请号:US12162068

    申请日:2007-01-25

    IPC分类号: C07C33/02

    摘要: Disclosed is a novel process for production of lasofoxifene, nafoxidine or an analogue thereof, which comprises reduced number of reaction steps, has a high efficiency, and is practically advantageous. For the production of lasofoxifene or an analogue thereof, a compound represented by the formula (4) is used as an intermediate. The compound represented by the formula (4) can be produced using compounds represented by the formulae (1) to (3) as starting compounds by performing the coupling of the three components in one step.

    摘要翻译: 本发明公开了一种生产拉索昔芬,nafoxidine或其类似物的新方法,其包括减少数量的反应步骤,具有高效率,并且实际上是有利的。 为了生产拉索昔芬或其类似物,使用由式(4)表示的化合物作为中间体。 由式(4)表示的化合物可以通过在一个步骤中进行三种成分的偶联而使用由式(1)至(3)表示的化合物作为起始化合物来制备。

    Process for Production of Lasofoxifene or Analogue Thereof
    2.
    发明申请
    Process for Production of Lasofoxifene or Analogue Thereof 有权
    拉索昔芬或其类似物的生产工艺

    公开(公告)号:US20090012314A1

    公开(公告)日:2009-01-08

    申请号:US12162068

    申请日:2007-01-25

    摘要: Disclosed is a novel process for production of lasofoxifene, nafoxidine or an analogue thereof, which comprises reduced number of reaction steps, has a high efficiency, and is practically advantageous. For the production of lasofoxifene or an analogue thereof, a compound represented by the formula (4) is used as an intermediate. The compound represented by the formula (4) can be produced using compounds represented by the formulae (1) to (3) as starting compounds by performing the coupling of the three components in one step.

    摘要翻译: 本发明公开了一种生产拉索昔芬,nafoxidine或其类似物的新方法,其包括减少数量的反应步骤,具有高效率,并且实际上是有利的。 为了生产拉索昔芬或其类似物,使用由式(4)表示的化合物作为中间体。 由式(4)表示的化合物可以通过在一个步骤中进行三种成分的偶联而使用由式(1)至(3)表示的化合物作为起始化合物来制备。

    Information processing apparatus, computer readable medium storing program, and information processing method
    3.
    发明授权
    Information processing apparatus, computer readable medium storing program, and information processing method 有权
    信息处理装置,计算机可读介质存储程序和信息处理方法

    公开(公告)号:US08693024B2

    公开(公告)日:2014-04-08

    申请号:US13187087

    申请日:2011-07-20

    申请人: Yoshiyuki Sano

    发明人: Yoshiyuki Sano

    摘要: An information processing apparatus includes an execution period specifying unit, a first calculation unit, and a second calculation unit. The execution period specifying unit specifies an execution period of each of plural image processing operations executed by plural image processing apparatuses within a given period of time in the past. The first calculation unit calculates an amount of power estimated to be consumed by a replaceable image processing apparatus executing the plural image processing operations if it is assumed that the plural image processing apparatuses have been replaced by the replaceable image processing apparatus within the given period of time. The second calculation unit calculates a total amount of power estimated to be consumed by the replaceable image processing apparatus if it is assumed that the plural image processing apparatuses have been replaced by the replaceable image processing apparatus within the given period of time.

    摘要翻译: 信息处理设备包括执行周期指定单元,第一计算单元和第二计算单元。 执行周期指定单元指定在过去的给定时间段内由多个图像处理设备执行的多个图像处理操作中的每一个的执行周期。 第一计算单元如果假设在给定时间段内已经替换了可替换图像处理装置的多个图像处理装置,则计算由执行多个图像处理操作的可更换图像处理装置所消耗的功率量 。 如果在给定的时间段内假设多个图像处理装置已经被可替换的图像处理装置替代,则第二计算单元计算估计为由可更换图像处理装置消耗的功率的总量。

    Metal-nanoparticle-containing composite, dispersion liquid thereof, and methods for producing the metal-nanoparticle-containing composite and the dispersion liquid
    4.
    发明授权
    Metal-nanoparticle-containing composite, dispersion liquid thereof, and methods for producing the metal-nanoparticle-containing composite and the dispersion liquid 有权
    含有金属纳米颗粒的复合物,其分散液,以及制备含金属纳米颗粒的复合物和分散液的方法

    公开(公告)号:US08388870B2

    公开(公告)日:2013-03-05

    申请号:US13502564

    申请日:2010-09-06

    IPC分类号: H01B1/22 B22F9/24 B22F1/02

    摘要: Provided are a composite of nanoparticles of a metal such as gold, silver, a platinum metal, or copper, and a polymer, the composite allowing formation of a metal film having a sufficiently low resistivity in terms of practicality simply by drying at room temperature without requiring any special heating-baking step or any step of removing a protective agent with a solvent; a dispersion liquid of the composite; methods for producing the foregoing; and a plastic substrate formed from the dispersion liquid. The composite comprises a (meth)acrylic-based copolymer having, as side chains, a polyethylene glycol chain and a phosphate residue represented by —OP(O)(OH)2 and having, at at least one end of the molecular chain, —SR (where R represents an alkyl group or the like).

    摘要翻译: 提供了金属,金,铂金属或铜等金属的纳米颗粒与聚合物的复合物,该复合物简单地通过在室温下干燥而形成具有足够低的电阻率的金属膜,而没有 需要任何特殊的加热烘烤步骤或用溶剂去除保护剂的任何步骤; 复合材料的分散液; 生产上述方法; 以及由分散液形成的塑料基板。 该复合材料包含(甲基)丙烯酸类共聚物,其具有作为侧链的聚乙二醇链和由-OP(O)(OH)2表示的磷酸酯残基,并且在分子链的至少一端具有 - SR(其中R表示烷基等)。

    Quarternary Ammonium Compound, Process for Producing the Same, Therapeutic Agent for Cerebrovascular Disorder, and Therapeutic Agent for Heart Disease
    5.
    发明申请
    Quarternary Ammonium Compound, Process for Producing the Same, Therapeutic Agent for Cerebrovascular Disorder, and Therapeutic Agent for Heart Disease 失效
    四季铵化合物,其制备方法,脑血管障碍治疗剂和心脏病治疗剂

    公开(公告)号:US20080269345A1

    公开(公告)日:2008-10-30

    申请号:US10594545

    申请日:2005-03-29

    摘要: A quaternary ammonium compound of the present invention is a quaternary ammonium compound represented by general formula (I) or (I′) (wherein, A represents a linear alkyl group having 1 to 4 carbon atoms, a branched alkyl group having 2 to 4 carbon atoms, a linear alkyl group having 1 to 4 carbon atoms and a hydroxyl group, or a branched alkyl group having 2 to 4 carbon atoms and a hydroxyl group, R1 to R3 may be the same or different and represent a linear or branched alkyl group having 1 to 12 carbon atoms, one of R4 to R8 represents CO2− or SO3−, while no more than three of the remaining R4 to R8 represent a group selected from the group consisting of a hydroxyl group and an alkoxy group having 1 to 4 carbon atoms, and other R4 to R8 represent a hydrogen atom, one of R′4 to R′8 represents CO2H or SO3H, no more than three of the remaining R′4 to R′8 represent a group selected from a protected hydroxyl group and an alkoxy group having 1 to 4 carbon atoms, while other R′4 to R′8 represent a hydrogen atom, and X− represents an anion capable of forming a salt with a quaternary ammonium group).

    摘要翻译: 本发明的季铵化合物是通式(I)或(I')表示的季铵化合物(其中,A表示碳原子数1〜4的直链烷基,碳原子数2〜4的支链烷基 原子,具有1至4个碳原子和羟基的直链烷基或具有2至4个碳原子和羟基的支链烷基,R 1至R 3, SUB>可以相同或不同,表示具有1至12个碳原子的直链或支链烷基,R 4至R 8中的一个表示CO 2 - 或SO 3 - ,而不超过三个剩余的R 4至R 8表示选自羟基和碳原子数1〜4的烷氧基的基团,以及其它R 4〜R 8, SUB>表示氢原子,R'4'至R'8之一表示CO 2 H或SO 3

    Phthalocyanine compound and production method therefor, and coloring composition containing the phthalocyanine compound
    6.
    发明授权
    Phthalocyanine compound and production method therefor, and coloring composition containing the phthalocyanine compound 有权
    酞菁化合物及其制备方法,以及含有酞菁化合物的着色组合物

    公开(公告)号:US08809427B2

    公开(公告)日:2014-08-19

    申请号:US13389283

    申请日:2010-08-06

    摘要: Provided is a phthalocyanine compound which is halogen-free and which has a green hue, excellent resistance to organic solvents and acids, and high chroma. Also provided are a metal-free phthalocyanine compound or a metal phthalocyanine compound represented by specified general formula (1-1) or (1-2) and having a N,N′-disubstituted imidazolone structure or piperazinedione structure introduced therein, and a coloring composition including the compound and a synthetic resin. The phthalocyanine compound of the present invention exhibits a clear green color and is halogen-free, and is thus useful as a clear green pigment for coloring materials such as a coating material, plastic, a printing ink, rubber, leather, textile printing, a color filter, a jet ink, a heat transfer ink, etc.

    摘要翻译: 提供一种无卤素的酞菁化合物,其具有绿色调,对有机溶剂和酸具有优异的耐受性和高色度。 还提供了不含金属的酞菁化合物或由特定的通式(1-1)或(1-2)表示并具有引入其中的N,N'-二取代的咪唑啉酮结构或哌嗪二酮结构的金属酞菁化合物, 包含该化合物和合成树脂的组合物。 本发明的酞菁化合物表现出清澈的绿色,为无卤素,因此可用作透明绿色颜料,用于着色材料如涂料,塑料,印刷油墨,橡胶,皮革,纺织品印花, 彩色滤光片,喷墨墨水,传热墨水等

    METAL-NANOPARTICLE-CONTAINING COMPOSITE, DISPERSION LIQUID THEREOF, AND METHODS FOR PRODUCING THE METAL-NANOPARTICLE-CONTAINING COMPOSITE AND THE DISPERSION LIQUID
    7.
    发明申请
    METAL-NANOPARTICLE-CONTAINING COMPOSITE, DISPERSION LIQUID THEREOF, AND METHODS FOR PRODUCING THE METAL-NANOPARTICLE-CONTAINING COMPOSITE AND THE DISPERSION LIQUID 有权
    含金属纳米复合材料,其分散液及其制备含金属纳米复合材料和分散液体的方法

    公开(公告)号:US20120280186A1

    公开(公告)日:2012-11-08

    申请号:US13502564

    申请日:2010-09-06

    IPC分类号: H01B1/02 B82Y40/00 B82Y30/00

    摘要: Provided are a composite of nanoparticles of a metal such as gold, silver, a platinum metal, or copper, and a polymer, the composite allowing formation of a metal film having a sufficiently low resistivity in terms of practicality simply by drying at room temperature without requiring any special heating-baking step or any step of removing a protective agent with a solvent; a dispersion liquid of the composite; methods for producing the foregoing; and a plastic substrate formed from the dispersion liquid. When a dispersion liquid of a metal-nanoparticle-containing composite that is prepared by reducing metal ions in an aqueous medium in the presence of a (meth)acrylic-based copolymer having, as side chains, a polyethylene glycol chain and a phosphate residue represented by —OP(O)(OH)2 and having, at at least one end of the molecular chain, —SR (where R represents an alkyl group or the like), is applied to a base material and is then just dried at room temperature, a film having conductivity is formed.

    摘要翻译: 提供了金属,金,铂金属或铜等金属的纳米颗粒与聚合物的复合物,该复合物简单地通过在室温下干燥而形成具有足够低的电阻率的金属膜,而没有 需要任何特殊的加热烘烤步骤或用溶剂去除保护剂的任何步骤; 复合材料的分散液; 生产上述方法; 以及由分散液形成的塑料基板。 当含有金属纳米粒子的复合材料的分散液体是通过在含有作为侧链的聚乙二醇链和磷酸酯残基的(甲基)丙烯酸类共聚物存在下在水性介质中还原金属离子制备的, 通过-OP(O)(OH)2,并且在分子链的至少一个末端具有-SR(其中R表示烷基等),并在室温下进行干燥 形成具有导电性的膜。

    Quaternary ammonium compound, process for producing the same, therapeutic agent for cerebrovascular disorder, and therapeutic agent for heart disease
    8.
    发明授权
    Quaternary ammonium compound, process for producing the same, therapeutic agent for cerebrovascular disorder, and therapeutic agent for heart disease 失效
    第四季铵化合物,其制备方法,脑血管障碍治疗剂和心脏病治疗剂

    公开(公告)号:US07687546B2

    公开(公告)日:2010-03-30

    申请号:US10594545

    申请日:2005-03-29

    IPC分类号: A01N33/12 A61K31/14

    摘要: A quaternary ammonium compound of the present invention is a quaternary ammonium compound represented by general formula (I) or (I′) (wherein, A represents a linear alkyl group having 1 to 4 carbon atoms, a branched alkyl group having 2 to 4 carbon atoms, a linear alkyl group having 1 to 4 carbon atoms and a hydroxyl group, or a branched alkyl group having 2 to 4 carbon atoms and a hydroxyl group, R1 to R3 may be the same or different and represent a linear or branched alkyl group having 1 to 12 carbon atoms, one of R4 to R8 represents CO2− or SO3−, while no more than three of the remaining R4 to R8 represent a group selected from the group consisting of a hydroxyl group and an alkoxy group having 1 to 4 carbon atoms, and other R4 to R8 represent a hydrogen atom, one of R′4 to R′8 represents CO2H or SO3H, no more than three of the remaining R′4 to R′8 represent a group selected from a protected hydroxyl group and an alkoxy group having 1 to 4 carbon atoms, while other R′4 to R′8 represent a hydrogen atom, and X− represents an anion capable of forming a salt with a quaternary ammonium group).

    摘要翻译: 本发明的季铵化合物是由通式(I)或(I')(表示的季铵化合物,其中,A表示具有1至4个碳原子,具有2-4个碳支链烷基的直链烷基 原子,碳原子数为1〜4的直链烷基和羟基的基团,或具有2至4个碳原子和羟基基团的支链烷基,R1至R3可以相同或不同,表示直链或支链的烷基 具有1至12个碳原子,R4中的一个来R8表示CO 2 - 或SO 3 - ,而不超过三个剩余的R 4至R 8中的表示选自羟基的基团和具有1至4的烷氧基中的基团 碳原子,并且另一个R 4至R 8表示氢原子,R'4中的一个来表示R 18 CO 2 H或SO 3 H,不超过三个剩余的R'4至R'8的表示从受保护的羟基中的基团 和具有1至4个碳原子的烷氧基,而其它R 4至R'8表示氢原子,X - 表示能够形成与季铵基团的盐)的阴离子。

    Composite of organic compound and copper nanoparticles, composite of organic compound and copper(I) oxide nanoparticles, and methods for producing the composites
    9.
    发明授权
    Composite of organic compound and copper nanoparticles, composite of organic compound and copper(I) oxide nanoparticles, and methods for producing the composites 有权
    有机化合物和铜纳米颗粒的复合物,有机化合物和氧化铜(I)纳米粒子的复合材料,以及复合材料的制备方法

    公开(公告)号:US08530559B2

    公开(公告)日:2013-09-10

    申请号:US13634344

    申请日:2011-02-28

    IPC分类号: C08K3/10

    摘要: Provided is a composite including copper nanoparticles or copper(I) oxide nanoparticles and a thioether-containing organic compound represented by X(OCH2CHR1)nOCH2CH(OH)CH2SZ [X represents an alkyl group; R1 represents a hydrogen atom or a methyl group; n represents an integer of 2 to 100; R1 is independent between repeating units and may be the same or different; and Z represents an alkyl group, an allyl group, an aryl group, an arylalkyl group, —R2—OH, —R2—NHR3, or —R2—(COR4)m (where R2 represents a saturated hydrocarbon group; R3 represents a hydrogen atom, an acyl group, an alkoxycarbonyl group, or a benzyloxycarbonyl group; R4 represents a hydroxy group, an alkyl group, or an alkoxy group; and m represents 1 to 3)]. Provided is a method for producing a composite of an organic compound and copper nanoparticles or a composite of an organic compound and copper(I) oxide nanoparticles, the method including reducing a copper compound in the presence of a thioether-containing organic compound represented by the general formula (1) above.

    摘要翻译: 提供了包含铜纳米颗粒或氧化铜(I)纳米颗粒和由X(OCH 2 CHR 1)n OCH 2 CH(OH)CH 2 SZ表示的含硫醚的有机化合物[X表示烷基; R1表示氢原子或甲基; n表示2〜100的整数, R1在重复单元之间是独立的,可以相同或不同; Z表示烷基,烯丙基,芳基,芳烷基,-R 2 -OH,-R 2 -NHR 3或-R 2 - (COR 4)m(其中,R 2表示饱和烃基; R 3表示氢 原子,酰基,烷氧基羰基或苄氧基羰基; R 4表示羟基,烷基或烷氧基,m表示1〜3)]。 本发明提供一种有机化合物和铜纳米粒子的复合体的制造方法或有机化合物与氧化铜(I)纳米粒子的复合体的制造方法,其特征在于,在含有硫化物的有机化合物 上述通式(1)。

    Semiconductor device having groups of element regions in the
semiconductor substrate
    10.
    发明授权
    Semiconductor device having groups of element regions in the semiconductor substrate 失效
    具有半导体衬底中的元件区域组的半导体器件

    公开(公告)号:US5729040A

    公开(公告)日:1998-03-17

    申请号:US704081

    申请日:1996-08-28

    申请人: Yoshiyuki Sano

    发明人: Yoshiyuki Sano

    CPC分类号: H01L27/0218

    摘要: A semiconductor device having the grounds of element regions are provided in a semiconductor substrate. The device comprises a semiconductor substrate of a first conductivity type, at least two element regions of a second conductivity type, provided in a semiconductor substrate and having grounds connected to said semiconductor substrate when said semiconductor substrate is set at a fixed potential and at least one ground-isolating well region of the second conductivity type, provided between said at least two element regions to electrically isolate said at least two element regions by forming a depletion layer between said at least two element regions when applied with a reverse bias voltage.

    摘要翻译: 具有元件区域的接地的半导体器件设置在半导体衬底中。 该装置包括:第一导电类型的半导体衬底,具有第二导电类型的至少两个元件区域,设置在半导体衬底中,并且当所述半导体衬底被设置在固定电位时具有连接到所述半导体衬底的接地,并且至少一个 设置在所述至少两个元件区域之间的第二导电类型的接地隔离阱区域,以在施加反向偏置电压时在所述至少两个元件区域之间形成耗尽层来电隔离所述至少两个元件区域。