公开(公告)号：US20230183770A1

公开(公告)日：2023-06-15

申请号：US17931352

申请日：2022-09-12

Applicant: ImmunityBio, Inc.

Inventor： Brett Morimoto ,  Kayvan Niazi ,  Annie Shin ,  Lise Geissert ,  Philip T. Liu

IPC: C12P19/34 ,  C12N9/12

CPC classification number: C12P19/34 ,  C12N9/1247 ,  C12N9/1241 ,  C12Y207/07019

Abstract: A method for the production of proteins used in the in vitro transcription (IVT) of messenger RNA (mRNA), wherein the proteins are evaluated for purity and efficacy by the efficiency with which mRNA synthetically derived therefrom, subsequently transfects cells and produces encoded proteins.