-
公开(公告)号：US12110419B2
公开(公告)日：2024-10-08
申请号：US17962071
申请日：2022-10-07
CPC分类号： C09D7/67 , C09D1/00 , C09D5/084 , C09D5/14 , C09D7/61 , C09D7/63 , C09D7/68 , C09D171/02 , C23C18/1212 , C23C18/1241 , C23C18/127
摘要： A method of making a silver-silicalite coating on a surface of a stainless-steel substrate is provided. The method includes mixing metakaolin with an aqueous solution of NaOH to form a first mixture. The method further includes mixing silica gel and silver nitrate with the first mixture to form a second mixture. Furthermore, the method includes mixing Zeolites Socony Mobil-5 (ZSM-5) with the second mixture to form a third mixture. The method further includes hydrothermally treating the stainless-steel substrate with the third mixture to form the silver-silicalite coating on the surface of the stainless-steel substrate. The hydrothermal treatment is carried out in the absence of an organic template. The stainless-steel substrate coated with the silver-silicalite coating, prepared by the method of the present disclosure, has lower corrosion in comparison to the same stainless-steel substrate without the silver-silicalite coating.
-
公开(公告)号：US11826477B1
公开(公告)日：2023-11-28
申请号：US17842876
申请日：2022-06-17
CPC分类号： A61K9/5115 , A61K31/05 , A61K31/12 , A61P33/00
摘要： A nanomedicinal composition comprising a nanocarrier and an antioxidant. The nanocarrier contains a metal organic framework and a porous silicate and/or aluminosilicate matrix. The antioxidant is disposed in the pores and/or on the surface of the nanocarrier by a solution phase impregnation process. The nanomedicinal composition is used in a method of treating Blastocystis infection.
-
公开(公告)号：US11738097B2
公开(公告)日：2023-08-29
申请号：US17938150
申请日：2022-10-05
IPC分类号： A61K9/00 , A61K49/04 , A61K49/18 , A61K49/08 , A61K47/68 , A61K47/69 , A61K31/12 , A61P35/00 , B82Y5/00
CPC分类号： A61K49/0428 , A61K31/12 , A61K47/6803 , A61K47/6883 , A61K47/6923 , A61K47/6929 , A61K49/08 , A61K49/1878 , A61P35/00 , B82Y5/00
摘要： Silica nanocarriers hybridized with superparamagnetic iron oxide nanoparticles (“SPIONs”) and curcumin through equilibrium or enforced adsorption technique. Methods for dual delivery of SPIONs and curcumin to a target for diagnosis or therapy, for example, for SPION-based magnetic resonance imaging or for targeted delivery of curcumin to a cell or tissue. The technique can be extend to co-precipitation of mixed metal oxide involving Ni, Mn, Co and Cu oxide. The calcination temperature can be varied from 500-900° C. The nanocombination is functionalized with chitosan, polyacrylic acid, PLGA or another agent to increase its biocompatibility in vivo.
-
4.发明授权公开(公告)号：US11471542B2
公开(公告)日：2022-10-18
申请号：US16055221
申请日：2018-08-06
IPC分类号： A61K9/00 , A61K49/04 , A61K49/18 , A61K49/08 , A61K47/68 , A61K47/69 , A61K31/12 , A61P35/00 , B82Y5/00
摘要： Silica nanocarriers hybridized with superparamagnetic iron oxide nanoparticles (“SPIONs”) and curcumin through equilibrium or enforced adsorption technique. Methods for dual delivery of SPIONs and curcumin to a target for diagnosis or therapy, for example, for SPION-based magnetic resonance imaging or for targeted delivery of curcumin to a cell or tissue. The technique can be extend to co-precipitation of mixed metal oxide involving Ni, Mn, Co and Cu oxide. The calcination temperature can be varied from 500-900° C. The nanocombination is functionalized with chitosan, polyacrylic acid, PLGA or another agent to increase its biocompatibility in vivo.
-
公开(公告)号：US11207348B2
公开(公告)日：2021-12-28
申请号：US16394543
申请日：2019-04-25
IPC分类号： A61K33/243 , A61K47/02 , A61P35/00 , A61K47/14 , B82Y5/00
摘要： A nanotherapeutic having platinum complexes encapsulated by a nanoformulation containing at least one spinel ferrite of formula CuFe2O4, NiFe2O4, CoFe2O4, and MnFe2O4 deposited on mesoporous silica. A method of preparing the nanotherapeutic that involves mixing a metal(II) salt and a Fe(III) salt with the mesoporous silica nanoparticles to form a powdery mixture, calcining the powdery mixture to form the nanoformulation, and mixing the nanoformulation with the platinum complex. A method for treating cancer with the nanotherapeutic.
-
公开(公告)号：US12109315B2
公开(公告)日：2024-10-08
申请号：US18193692
申请日：2023-03-31
CPC分类号： A61K9/5115 , A61K31/05 , A61K31/12 , A61P33/00
摘要： A nanomedicinal composition comprising a nanocarrier and an antioxidant. The nanocarrier contains a metal organic framework and a porous silicate and/or aluminosilicate matrix. The antioxidant is disposed in the pores and/or on the surface of the nanocarrier by a solution phase impregnation process. The nanomedicinal composition is used in a method of treating Blastocystis infection.
-
公开(公告)号：US11865193B2
公开(公告)日：2024-01-09
申请号：US18450737
申请日：2023-08-16
IPC分类号： A61K9/00 , A61K49/04 , A61K49/18 , A61K49/08 , A61K47/68 , A61K47/69 , A61K31/12 , A61P35/00 , B82Y5/00
CPC分类号： A61K49/0428 , A61K31/12 , A61K47/6803 , A61K47/6883 , A61K47/6923 , A61K47/6929 , A61K49/08 , A61K49/1878 , A61P35/00 , B82Y5/00
摘要： Silica nanocarriers hybridized with superparamagnetic iron oxide nanoparticles (“SPIONs”) and curcumin through equilibrium or enforced adsorption technique. Methods for dual delivery of SPIONs and curcumin to a target for diagnosis or therapy, for example, for SPION-based magnetic resonance imaging or for targeted delivery of curcumin to a cell or tissue. The technique can be extend to co-precipitation of mixed metal oxide involving Ni, Mn, Co and Cu oxide. The calcination temperature can be varied from 500-900° C. The nanocombination is functionalized with chitosan, polyacrylic acid, PLGA or another agent to increase its biocompatibility in vivo.
-
公开(公告)号：US11701438B2
公开(公告)日：2023-07-18
申请号：US17938155
申请日：2022-10-05
IPC分类号： A61K9/00 , A61K49/04 , A61K49/18 , A61K49/08 , A61K47/68 , A61K47/69 , A61K31/12 , A61P35/00 , B82Y5/00
CPC分类号： A61K49/0428 , A61K31/12 , A61K47/6803 , A61K47/6883 , A61K47/6923 , A61K47/6929 , A61K49/08 , A61K49/1878 , A61P35/00 , B82Y5/00
摘要： Silica nanocarriers hybridized with superparamagnetic iron oxide nanoparticles (“SPIONs”) and curcumin through equilibrium or enforced adsorption technique. Methods for dual delivery of SPIONs and curcumin to a target for diagnosis or therapy, for example, for SPION-based magnetic resonance imaging or for targeted delivery of curcumin to a cell or tissue. The technique can be extend to co-precipitation of mixed metal oxide involving Ni, Mn, Co and Cu oxide. The calcination temperature can be varied from 500-900° C. The nanocombination is functionalized with chitosan, polyacrylic acid, PLGA or another agent to increase its biocompatibility in vivo.
-
公开(公告)号：US11123309B2
公开(公告)日：2021-09-21
申请号：US16191692
申请日：2018-11-15
摘要： The invention is directed to hierarchical aluminosilicates that contain both micro- and meso-pores, to methods for loading and delivering poorly soluble antioxidants such as CoQ10 and curcumin to subjects, and to a top-down method for producing hierarchical aluminosilicates.
-
公开(公告)号：US12102651B1
公开(公告)日：2024-10-01
申请号：US18739378
申请日：2024-06-11
IPC分类号： A61K33/38 , A61K33/243 , A61K47/02 , A61P31/04
CPC分类号： A61K33/38 , A61K33/243 , A61K47/02 , A61P31/04
摘要： A medicinal nanocomposite is provided. The medicinal nanocomposite includes 80 to 99 wt. % carrier particles of a porous silicate material selected from a group including mesoporous silica, silicalite, mesosilicalite, silver-incorporated silicalite, and silver-incorporated mesosilicalite, the carrier particles comprising a pore framework, 0.5 to 10 wt. % silver nanoparticles (Ag NPs) disposed the pore framework, and 0.5 to 10 wt. % of a platinum-containing pharmaceutical compound disposed on at least one surface selected from an interior pore surface of the carrier particles, an exterior surface of the carrier particles, and a surface of the silver nanoparticles. The medicinal nanocomposite releases less than 10 mole % of the platinum-containing pharmaceutical compound after 60 to 84 hours at a pH of 4.5 to 7, based on an initial amount of the platinum-containing pharmaceutical compound present in the medicinal nanocomposite.
-
-
-
-
-
-
-
-
-
搜索结果
22 条记录 (耗时 0.026 秒)
