-
公开(公告)号：US11291998B2
公开(公告)日：2022-04-05
申请号：US17165757
申请日：2021-02-02
发明人： Wesley A. Cox-Muranami , Darren Robert Segale , Oliver Jon Miller , Jennifer Olivia Foley , Tarun Kumar Khurana , Paul Crivelli , Gary Watts
摘要： An apparatus for directing fluid into and out of a fluidic device includes two or more fluid prime channels connected to a fluid inlet of the fluidic device, a flow control valve for each fluid prime channel to control flow between the fluid prime channel and the fluid inlet, one or more outlet channels connected to a fluid outlet of the fluidic device, and a flow control valve for each outlet channel to control flow between the fluid outlet and the associated outlet channel. An apparatus for delivering fluids to a fluid inlet includes a plate that is rotatable about an axis of rotation and a plurality of fluid compartments disposed on the plate, each compartment having a fluid exit port disposed at a common radial distance from the axis of rotation and positioned to align with the fluid inlet as the plate rotates about the axis of rotation.
-
公开(公告)号：US20210154667A1
公开(公告)日：2021-05-27
申请号：US17165757
申请日：2021-02-02
发明人： Wesley A. Cox-Muranami , Darren Robert Segale , Oliver Jon Miller , Jennifer Olivia Foley , Tarun Kumar Khurana , Paul Crivelli , Gary Watts
摘要： An apparatus for directing fluid into and out of a fluidic device includes two or more fluid prime channels connected to a fluid inlet of the fluidic device, a flow control valve for each fluid prime channel to control flow between the fluid prime channel and the fluid inlet, one or more outlet channels connected to a fluid outlet of the fluidic device, and a flow control valve for each outlet channel to control flow between the fluid outlet and the associated outlet channel. An apparatus for delivering fluids to a fluid inlet includes a plate that is rotatable about an axis of rotation and a plurality of fluid compartments disposed on the plate, each compartment having a fluid exit port disposed at a common radial distance from the axis of rotation and positioned to align with the fluid inlet as the plate rotates about the axis of rotation.
-
公开(公告)号：US10953399B2
公开(公告)日：2021-03-23
申请号：US16244776
申请日：2019-01-10
发明人： Wesley A. Cox-Muranami , Darren Robert Segale , Oliver Jon Miller , Jennifer Olivia Foley , Tarun Kumar Khurana , Paul Crivelli , Gary Watts
摘要： An apparatus for directing fluid into and out of a fluidic device includes two or more fluid prime channels connected to a fluid inlet of the fluidic device, a flow control valve for each fluid prime channel to control flow between the fluid prime channel and the fluid inlet, one or more outlet channels connected to a fluid outlet of the fluidic device, and a flow control valve for each outlet channel to control flow between the fluid outlet and the associated outlet channel. An apparatus for delivering fluids to a fluid inlet includes a plate that is rotatable about an axis of rotation and a plurality of fluid compartments disposed on the plate, each compartment having a fluid exit port disposed at a common radial distance from the axis of rotation and positioned to align with the fluid inlet as the plate rotates about the axis of rotation.
-
公开(公告)号：US11885323B2
公开(公告)日：2024-01-30
申请号：US16874934
申请日：2020-05-15
申请人： Illumina, Inc.
CPC分类号： F04B43/1223 , F04B43/06
摘要： Linear peristaltic pumps for use with fluidic cartridges. An apparatus includes a reagent cartridge configured to be received within a cartridge receptacle of a system. The reagent cartridge includes a reagent reservoir and a body including a surface that forms depressions. Each depression has a fluid inlet and a fluid outlet and is fluidly coupled to at least one other depression. The reagent cartridge also includes a deformable material coupled to the surface of the body and includes portions. Each portion covers one of the depressions to define chambers. The portions of the deformable material are movable relative to the depressions between a first position outside of a dimensional envelope of the body and a second position within the dimensional envelope of the body.
-
公开(公告)号：US20220291250A1
公开(公告)日：2022-09-15
申请号：US17831222
申请日：2022-06-02
申请人： Illumina, Inc.
IPC分类号： G01N35/10
摘要： An apparatus includes a fluidic circuit, a bypass fluidic circuit, a first set of fluid wells, a second set of fluid wells, a first valve, and a second valve. The first valve operatively associated with the first set of fluid wells such that the first selectively fluidly connects any one of the first set of fluid wells to a first valve outlet. The second valve operatively associated with the fluidic circuit, the bypass fluidic circuit, the first valve outlet, and the second set of fluid wells such that the second valve selectively fluidly connects any one of the second set of fluid wells and the first valve outlet to the fluidic circuit or the first valve outlet to the bypass fluidic circuit.
-
公开(公告)号：US12000854B2
公开(公告)日：2024-06-04
申请号：US17831222
申请日：2022-06-02
申请人： Illumina, Inc.
IPC分类号： G01N35/10
CPC分类号： G01N35/1097
摘要： An apparatus includes a fluidic circuit, a bypass fluidic circuit, a first set of fluid wells, a second set of fluid wells, a first valve, and a second valve. The first valve operatively associated with the first set of fluid wells such that the first selectively fluidly connects any one of the first set of fluid wells to a first valve outlet. The second valve operatively associated with the fluidic circuit, the bypass fluidic circuit, the first valve outlet, and the second set of fluid wells such that the second valve selectively fluidly connects any one of the second set of fluid wells and the first valve outlet to the fluidic circuit or the first valve outlet to the bypass fluidic circuit.
-
公开(公告)号：US20230031325A1
公开(公告)日：2023-02-02
申请号：US17790058
申请日：2020-12-18
申请人： ILLUMINA, INC.
IPC分类号： B01L3/00
摘要： Actuation systems and methods for use with flow cells. In accordance with an implementation, a method includes moving, using an actuator disposed within a manifold assembly, a membrane portion of a membrane of the manifold assembly away from a valve seat to enable fluidic flow from a reagent fluidic line to a common fluidic line. The membrane portion and the valve seat forming a membrane valve. The reagent fluidic line being fluidically coupled to a reagent reservoir. The common fluidic line being fluidically coupled to a flow cell. The common fluidic line has a common central axis and the reagent fluidic line has a reagent central axis that is non-collinear with the common central axis. The method includes urging the membrane portion against the valve seat to prevent fluidic flow from the reagent fluidic line to the common fluidic line.
-
公开(公告)号：US20210197200A1
公开(公告)日：2021-07-01
申请号：US17115454
申请日：2020-12-08
申请人： ILLUMINA, INC.
发明人： Wesley A. Cox-Muranami , Cameron Mar , Cyril Delattre , Paul Crivelli , Kamal Shah , Kirkpatrick W. Norton
IPC分类号： B01L3/00 , G01N27/327
摘要： Systems for monitoring fluidics in reagent cartridges and related methods. An apparatus includes a system includes a reagent cartridge receptacle and a flow cell assembly. The apparatus includes a reagent cartridge receivable within the reagent cartridge receptacle and adapted to carry the flow cell assembly. The reagent cartridge includes a reagent reservoir fluidically coupled to the flow cell assembly. The apparatus includes a sensor module adapted to be positioned adjacent the reagent reservoir. The sensor module is adapted to generate a signal associated with a volume of reagent contained within the reagent reservoir.
-
公开(公告)号：US20240299930A1
公开(公告)日：2024-09-12
申请号：US18668787
申请日：2024-05-20
申请人： ILLUMINA, INC.
IPC分类号： B01L3/00
CPC分类号： B01L3/502 , B01L2200/16 , B01L2300/042 , B01L2300/044 , B01L2300/047 , B01L2300/14 , B01L2400/0475 , B01L2400/06
摘要： Two-phase flushing systems and methods. An example method includes moving a valve to a first position to fluidly connect a first reagent reservoir containing a first reagent to a flow cell and flowing the first reagent from the first reagent reservoir to the flow cell to perform a biochemical reaction. The method includes moving the valve to a second position to fluidly connect a gas to the flow cell and flowing gas into the flow cell to expel at least a portion of the first reagent from the biochemical reaction from the flow cell. The method includes moving the valve to a third position to fluidly connect a buffer reagent reservoir containing a buffer reagent to the flow cell and flowing the buffer reagent into the flow cell.
-
公开(公告)号：US11426723B2
公开(公告)日：2022-08-30
申请号：US16584353
申请日：2019-09-26
申请人： Illumina, Inc.
发明人： Wesley A. Cox-Muranami , Kay Klausing , Bradley Kent Drews , Nicholas Watson , Jennifer Olivia Foley , Murphy Hitchcock , Paul Sangiorgio , Sz-Chin Steven Lin
IPC分类号： B01L3/00
摘要： A system includes a fluidic device, a flow control valve, a first reagent fluid reservoir fluidly connectable to the fluidic device by the flow control valve, a first fluid buffer reservoir fluidly connectable to the fluidic device by the flow control valve, and a common fluid buffer source fluidly connectable to the fluidic device by the flow control valve. The flow control valve permits flow comprising: (i) flow from the first reagent fluid reservoir to the fluidic device, (ii) flow from the common fluid buffer source to the fluidic device, (iii) flow from the fluidic device to the first fluid buffer reservoir, (iv) flow from the first reagent fluid reservoir to the fluidic device, and (v) flow from the first fluid buffer reservoir to the fluidic device.
-
-
-
-
-
-
-
-
-
搜索结果
18 条记录 (耗时 0.017 秒)
