公开(公告)号：US20180169048A1

公开(公告)日：2018-06-21

申请号：US15127717

申请日：2015-03-17

Applicant: ISIS Innovation Limited

Inventor： David Smith ,  Fredrik Jerneren ,  Helga Refsum

IPC: A61K31/202 ,  A61K31/519 ,  A61K31/714 ,  A61K31/232 ,  A61K31/4415 ,  A61K9/00 ,  A61K31/205 ,  A61K31/14 ,  A61P25/28

CPC classification number: A61K31/202 ,  A61K9/0053 ,  A61K31/14 ,  A61K31/205 ,  A61K31/232 ,  A61K31/4415 ,  A61K31/519 ,  A61K31/714 ,  A61P25/28 ,  A61K2300/00

Abstract: The present invention provides a combined therapy comprising the use of one or more omega-3 fatty acids and one or more B vitamins and for treating cognitive impairment, such cognitive impairment disorders include, especially but not exclusively, Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD). The present invention also provides a treatment: for individuals suffering from cognitive impairment disorders that occur as a result of brain or cerebral atrophy, the invention includes inter alma methods of treating and/or reducing progression of brain atrophy and pharmaceutical compositions and nutritional supplements therefor.

公开(公告)号：US10966947B2

公开(公告)日：2021-04-06

申请号：US15127717

申请日：2015-03-17

Applicant: ISIS Innovation Limited

Inventor： David Smith ,  Fredrik Jerneren ,  Helga Refsum

IPC: A61K31/202 ,  A61K31/519 ,  A61K31/714 ,  A61P25/28 ,  A61K31/4415 ,  A61K9/00 ,  A61K31/14 ,  A61K31/205 ,  A61K31/232

Abstract: The present invention provides a combined therapy comprising the use of one or more omega-3 fatty acids and one or more B vitamins and for treating cognitive impairment, such cognitive impairment disorders include, especially but not exclusively, Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD). The present invention also provides a treatment for individuals suffering from cognitive impairment disorders that occur as a result of brain or cerebral atrophy, the invention includes inter alma methods of treating and/or reducing progression of brain atrophy and pharmaceutical compositions and nutritional supplements therefor.