公开(公告)号：US20190002927A1

公开(公告)日：2019-01-03

申请号：US16023055

申请日：2018-06-29

Applicant: INVISTA NORTH AMERICA S.A.R.L.

Inventor： Alexander Brett Foster ,  Leonard Keith Pattenden ,  Jonathan David Rand ,  Ana Teresa dos Santos Brito Mendes Roberts ,  Andrew Shaw ,  Mark Paul Taylor

IPC: C12P5/00 ,  C12N9/10 ,  C12N9/88 ,  C12N1/20

Abstract: Systems, networks, methods, compositions and recombinant hosts for biosynthesizing hydrocarbons from a feedstock, such as gas, are provided.

公开(公告)号：US20180094282A1

公开(公告)日：2018-04-05

申请号：US15717065

申请日：2017-09-27

Applicant: INVISTA NORTH AMERICA S.A.R.L.

Inventor： Stephen Thomas Cartman ,  Alexander Brett Foster ,  Ana Teresa dos Santos Brito Mendes ,  Mark Paul Taylor

IPC: C12P5/00 ,  C12R1/01

Abstract: Methods and compositions for synthesizing dienes and derivative thereof, such as isoprene, in Cupriavidus necator are provided.

公开(公告)号：US20190338320A1

公开(公告)日：2019-11-07

申请号：US16399155

申请日：2019-04-30

Applicant: INVISTA NORTH AMERICA S.A.R.L.

Inventor： Alexander Brett FOSTER ,  Cristina Serrano AMATRIAIN ,  Gary J. Smith ,  Paul Sheldon Pearlman ,  Mark Paul Taylor

IPC: C12P7/62

Abstract: Provided herein are methods for generating cellular biomass in continuous aerobic fermentation systems. The biomass yield, and the concentration of polyhydroxyalkanoate within the biomass, are each directed to advantageous levels by operating the continuous fermentation system under particular nutrient limitation conditions. Also provided are biomass produced using the provided methods, and animal feed compositions including the provided biomass.

公开(公告)号：US10538788B2

公开(公告)日：2020-01-21

申请号：US15717065

申请日：2017-09-27

Applicant: INVISTA NORTH AMERICA S.A.R.L.

Inventor： Stephen Thomas Cartman ,  Alexander Brett Foster ,  Ana Teresa dos Santos Brito Mendes Roberts ,  Mark Paul Taylor

IPC: C12N9/88 ,  C12P5/00 ,  C12R1/01 ,  C07C11/12 ,  C08F136/08 ,  C12N9/90 ,  C12N15/74

Abstract: Methods and compositions for synthesizing dienes and derivative thereof, such as isoprene, in Cupriavidus necator are provided.

公开(公告)号：US20190352674A1

公开(公告)日：2019-11-21

申请号：US16399145

申请日：2019-04-30

Applicant: INVISTA NORTH AMERICA S.A.R.L.

Inventor： Alexander Brett FOSTER ,  Cristina Serrano AMATRIAIN ,  Gary J. Smith ,  Paul Sheldon Pearlman ,  Mark Paul Taylor ,  Jonathan Combe ,  Daniel Bawdon

IPC: C12P7/04 ,  C12N1/20 ,  C12P7/06 ,  C12P7/42 ,  C12N9/10 ,  C12N9/88 ,  C12N9/04

Abstract: Provided herein are methods for increasing the yield of an extracellular product synthesized by an organism cultured in a continuous aerobic fermentation system. The extracellular product yield is increased through the use of an organism modified to decreased production of polyhydroxyalkanoate, to increase production of the extracellular product, and to include promoters that can be inducible in response to nutrient limitation conditions. The extracellular product yield is also increased by operating the continuous fermentation system under particular nutrient limitation conditions. Also provided are non-naturally occurring organisms that have been modified for use with the provided methods, and extracellular products made using the provided methods.

公开(公告)号：US20190218577A1

公开(公告)日：2019-07-18

申请号：US16337481

申请日：2017-09-27

Applicant: INVISTA NORTH AMERICA S.A.R.L.

Inventor： Stephen Thomas Cartman ,  Alexander Brett Foster ,  Ana Teresa De Santos Brito Mendes Roberts ,  Mark Paul Taylor

IPC: C12P5/00 ,  C12N9/90 ,  C12N9/88 ,  C07C11/12 ,  C08F136/08

CPC classification number: C12P5/007 ,  C07C11/12 ,  C08F136/08 ,  C12N9/88 ,  C12N9/90 ,  C12N15/74 ,  C12N2330/30 ,  C12P5/026 ,  C12R1/01 ,  C12Y402/03027 ,  C12Y503/03002 ,  Y02E50/343

Abstract: Methods and compositions for synthesizing dienes and derivative thereof, such as isoprene, in Cupriavidus necator are provided.