公开(公告)号：US20180140721A1

公开(公告)日：2018-05-24

申请号：US15807350

申请日：2017-11-08

Applicant: Intrexon Corporation

Inventor： Stephen SCHAUER ,  Darby THOMAS ,  Gregory ROBINSON ,  Mark PYKETT ,  Richard THORN ,  Kirsten GRUIS

IPC: A61K48/00 ,  C07K14/47 ,  C12N15/86 ,  A61K38/17 ,  A61P25/00

CPC classification number: A61K48/0058 ,  A61K38/1709 ,  A61K48/005 ,  A61K48/0066 ,  A61K48/0075 ,  A61P25/00 ,  C07K14/47 ,  C12N15/86 ,  C12N2750/14143 ,  C12N2830/002

Abstract: The invention provides polynucleotides, vectors and viruses expressing frataxin and methods of treating Friedreich's Ataxia.

公开(公告)号：US20190233834A1

公开(公告)日：2019-08-01

申请号：US16316783

申请日：2017-07-25

Applicant: INTREXON CORPORATION

Inventor： Sekhar BODDUPALLI ,  Andrey BOUKHAROV ,  Rio STAMLER ,  Zhongsen LI ,  Arianne TREMBLAY ,  Stephen SCHAUER ,  Shiv B. TIWARI ,  John SALMERON

IPC: C12N15/82

CPC classification number: C12N15/8217 ,  C12N15/8218 ,  C12N15/825 ,  C12N15/827 ,  C12N15/8273 ,  C12N15/8274 ,  C12N15/8281 ,  C12N15/8282 ,  C12N15/8283 ,  C12N15/8286

Abstract: The invention provides a compositions and methods for controlling phenotypic traits in plants. Genes of interest are placed under the control of a gene switch to allow inducible control or expression of a gene of interest “on-demand” by treatment of the plant with a chemical ligand.