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公开(公告)号:US11648083B2
公开(公告)日:2023-05-16
申请号:US16284836
申请日:2019-02-25
申请人: INTER-MED, INC.
发明人: Gary J. Pond , John Baeten , Michael W. Allen
IPC分类号: A61C1/07 , B06B1/02 , A61C1/00 , A61C17/02 , A61N7/00 , H01L41/04 , H01L41/09 , A61C5/40 , A61C5/50
CPC分类号: A61C1/07 , A61C1/0015 , A61C17/0202 , A61N7/00 , B06B1/0207 , H01L41/042 , H01L41/09 , A61C5/40 , A61C5/50
摘要: The present disclosure provides a device having a circuit. The circuit includes at least one boost converter receiving power from an energy source, a square wave driver in series with the boost converter, an inductor in series with the square wave driver for converting a square wave to a sinusoidal wave, and a piezoelectric transducer in series with the inductor, the piezoelectric transducer connectable to a load. The device further includes a phase-locked loop coupled to the circuit to determine a resonance frequency of the piezoelectric transducer when the piezoelectric transducer is connected to the load.
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公开(公告)号:US11590517B2
公开(公告)日:2023-02-28
申请号:US17929187
申请日:2022-09-01
申请人: Inter-Med, Inc.
发明人: John Baeten , Alexander D. Johnson
摘要: An applicator for a syringe is provided that includes a hub configured to be disposed at least partially within a nozzle of the syringe and defining a fluid passage therethrough, with one or barbs on the hub that frictionally and sealingly engage an interior of the nozzle in a manner minimizing void space associated with waste of deliverable material, and an applicator tip extending distally from the hub. The barb(s) may have varying diameters in order to enable the applicator to be engaged and utilized with syringes having different diameter nozzles. Further the fluid passage through the hub and applicator tip is dimensioned to minimize the volume of material that is retained within the applicator after use, thereby increasing the volume of material that can dispensed from the syringe for use in a procedure or procedures and minimize waste.
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公开(公告)号:US20180169344A1
公开(公告)日:2018-06-21
申请号:US15384797
申请日:2016-12-20
申请人: Inter-Med, Inc.
发明人: Brett Arand , John Baeten , Gary Pond
IPC分类号: A61M5/315
CPC分类号: A61M5/31513 , A61M5/31515 , A61M5/3158 , A61M2005/3103
摘要: In the present invention, a dripless syringe is provided that includes a barrel having fluid therein, the barrel defining an open end and a nozzle opposite the open end, a plunger disposed at least partially within the open end and including a body and a push pin extending from one end of the body, a seal plate slidably mounted to the push pin and a bung disposed over the seal plate and the push pin and sealingly engaged between the seal plate and the barrel the seal plate enables the bung to remain in sealing engagement with the interior of the barrel while the plunger is moved within the barrel. Further, when pressure is removed to cease dispensing of the fluid, the pin allows the bung to retract and provide a negative pressure on the fluid to prevent drips of fluid from leaking out of the nozzle.
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公开(公告)号:US20230240796A1
公开(公告)日:2023-08-03
申请号:US18133414
申请日:2023-04-11
申请人: INTER-MED, INC.
发明人: Gary J. Pond , John Baeten , Michael W. Allen
CPC分类号: A61C1/07 , B06B1/0207 , A61C1/0015 , H10N30/20 , H10N30/802 , A61C17/0202 , A61N7/00 , A61C5/40
摘要: The present disclosure provides a device having a circuit. The circuit includes at least one boost converter receiving power from an energy source, a square wave driver in series with the boost converter, an inductor in series with the square wave driver for converting a square wave to a sinusoidal wave, and a piezoelectric transducer in series with the inductor, the piezoelectric transducer connectable to a load. The device further includes a phase-locked loop coupled to the circuit to determine a resonance frequency of the piezoelectric transducer when the piezoelectric transducer is connected to the load.
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公开(公告)号:US20180203011A1
公开(公告)日:2018-07-19
申请号:US15920646
申请日:2018-03-14
申请人: Inter-Med, Inc.
发明人: Gary Pond , John Baeten
IPC分类号: G01N33/574 , A61K49/00 , A61B5/00 , A61B50/33
CPC分类号: G01N33/57407 , A61B5/0071 , A61B5/0088 , A61B50/33 , A61B2562/0233 , A61K49/0056 , G01N2333/42
摘要: Methods and kits for assessing the presence of, and for detecting cancer, notably oral cancer, are disclosed. Such methods and kits use one or more lectins operably linked to a fluorophore, wherein the lectin binds differentially to cancerous and non-cancerous tissues, and wherein the fluorophore facilitates visualizing the differential binding. The lectins are applied to the oral mucosa of a subject, the fluorophore is exposed to light, and cancerous regions of the mucosa are visualized. In certain embodiments, the lectin specifically binds to one or more of a β-galactoside, an α- or β-N-acetylglucosamine, or a sialic acid moiety.
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公开(公告)号:US20160018398A1
公开(公告)日:2016-01-21
申请号:US14869316
申请日:2015-09-29
申请人: Inter-Med, Inc.
发明人: Gary Pond , John Baeten
IPC分类号: G01N33/574 , A61B5/00 , A61B19/02 , A61K49/00
CPC分类号: G01N33/57407 , A61B5/0071 , A61B5/0088 , A61B50/33 , A61B2562/0233 , A61K49/0056 , G01N2333/42
摘要: Methods and kits for assessing the presence of, and for detecting cancer, notably oral cancer, are disclosed. Such methods and kits use one or more lectins operably linked to a fluorophore, wherein the lectin binds differentially to cancerous and non-cancerous tissues, and wherein the fluorophore facilitates visualizing the differential binding. The lectins are applied to the oral mucosa of a subject, the fluorophore is exposed to light, and cancerous regions of the mucosa are visualized. In certain embodiments, the lectin specifically binds to one or more of a β-galactoside, an α- or β-N-acetylglucosamine, or a sialic acid moiety.
摘要翻译: 公开了用于评估癌症,特别是口腔癌的存在和用于检测癌症的方法和试剂盒。 这样的方法和试剂盒使用与荧光团可操作地连接的一种或多种凝集素,其中所述凝集素与癌和非癌组织差异性结合,并且其中所述荧光团有助于显现差异结合。 将凝集素应用于受试者的口腔粘膜,荧光团暴露于光,并且粘膜的癌性区域可视化。 在某些实施方案中,凝集素特异性结合一种或多种β-半乳糖苷,α-或β-葡糖基-N-乙酰氨基葡萄糖或唾液酸部分。
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公开(公告)号:US20240000669A1
公开(公告)日:2024-01-04
申请号:US18250642
申请日:2021-10-26
申请人: INTER-MED, INC.
发明人: John Baeten , Thomas KANDATHIL , Alex JOHNSON , Katherine BARRY
IPC分类号: A61K6/52
CPC分类号: A61K6/52
摘要: A medicament for dental procedures includes a first component comprising an oxidizing agent, and a second component comprising a calcium complexing agent, wherein when the first component is mixed with the second component, the pH is greater than 6.2. Kits including the medicament and methods of use of the medicament are disclosed.
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公开(公告)号:USD961044S1
公开(公告)日:2022-08-16
申请号:US29792885
申请日:2022-04-28
申请人: Inter-Med, Inc.
设计人: John Baeten , Alexander D. Johnson
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公开(公告)号:USD958929S1
公开(公告)日:2022-07-26
申请号:US29692825
申请日:2019-05-29
申请人: Inter-Med, Inc.
设计人: John Baeten , Alexander D. Johnson
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公开(公告)号:USD888956S1
公开(公告)日:2020-06-30
申请号:US29648024
申请日:2018-05-17
申请人: Inter-Med, Inc.
设计人: John Baeten , Alexander Johnson , Brett Arand
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