公开(公告)号：US20180355036A1

公开(公告)日：2018-12-13

申请号：US16066688

申请日：2016-12-20

Applicant: INNATE PHARMA

Inventor： LAURENT GAUTHIER ,  NADIA ANCERIZ ,  ARIANE MOREL ,  BENJAMIN ROSSI

IPC: C07K16/28 ,  C07K16/46

CPC classification number: C07K16/2803 ,  C07K16/2809 ,  C07K16/2887 ,  C07K16/468 ,  C07K2317/24 ,  C07K2317/31 ,  C07K2317/33 ,  C07K2317/34 ,  C07K2317/526 ,  C07K2317/622 ,  C07K2317/732 ,  C07K2317/92

Abstract: NKp-46-binding immunoglobulin variable regions, and proteins such as antibodies and multispecific proteins that comprise the variable regions are provided. The proteins can bind and specifically redirect NK cells to lyse a target cell of interest. The proteins have utility in the treatment of disease, notably cancer or infectious disease.

公开(公告)号：US20240174748A1

公开(公告)日：2024-05-30

申请号：US18432126

申请日：2024-02-05

Applicant: INNATE PHARMA

Inventor： LAURENT GAUTHIER ,  NADIA ANCERIZ ,  ARIANE MOREL ,  BENJAMIN ROSSI

IPC: C07K16/28 ,  C07K16/46 ,  C12N5/10 ,  C12N15/00 ,  C12N15/64 ,  C12N15/66

CPC classification number: C07K16/2803 ,  C07K16/2809 ,  C07K16/2887 ,  C07K16/468 ,  C12N5/10 ,  C12N15/00 ,  C12N15/64 ,  C12N15/66 ,  C07K2317/24 ,  C07K2317/31 ,  C07K2317/33 ,  C07K2317/34 ,  C07K2317/526 ,  C07K2317/622 ,  C07K2317/732 ,  C07K2317/92 ,  C12N2511/00 ,  C12N2523/00

Abstract: The application pertains to NKp46-binding immunoglobulin variable regions, and proteins such as antibodies and multispecific proteins that comprise the variable regions. The proteins can bind and specifically redirect NK cells to lyse a target cell of interest. The proteins have utility in the treatment of disease, notably cancer or infectious disease.

公开(公告)号：US20210269523A1

公开(公告)日：2021-09-02

申请号：US17315547

申请日：2021-05-10

Applicant: INNATE PHARMA

Inventor： LAURENT GAUTHIER ,  NADIA ANCERIZ ,  ARIANE MOREL ,  BENJAMIN ROSSI

IPC: C07K16/28 ,  C07K16/46

Abstract: NKp46-binding immunoglobulin variable regions, and proteins such as antibodies and multispecific proteins that comprise the variable regions are provided. The proteins can bind and specifically redirect NK cells to lyse a target cell of interest. The proteins have utility in the treatment of disease, notably cancer or infectious disease.