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1.发明公开公开(公告)号：US20240083969A1
公开(公告)日：2024-03-14
申请号：US18321820
申请日：2023-05-23
发明人： Heiko SCHUSTER , Daniel Johannes KOWALEWSKI , Oliver SCHOOR , Jens FRITSCHE , Toni WEINSCHENK , Harpreet SINGH , Gisela SCHIMMACK , Michael ROEMER
IPC分类号： C07K14/725 , A61K9/19 , A61K35/17 , A61K39/00 , A61P35/00 , C07K14/74 , C07K16/28 , C12N5/0783 , C12N15/115 , G01N33/574 , G16B25/10
CPC分类号： C07K14/7051 , A61K9/19 , A61K35/17 , A61K39/001111 , A61P35/00 , C07K14/70539 , C07K16/2809 , C07K16/2833 , C12N5/0638 , C12N15/115 , G01N33/57492 , G16B25/10 , A61K38/00
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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公开(公告)号：US20230227518A1
公开(公告)日：2023-07-20
申请号：US18161423
申请日：2023-01-30
发明人： Colette SONG , Franziska HOFFGAARD , Daniel Johannes KOWALEWSKI , Oliver SCHOOR , Jens FRITSCHE , Toni WEINSCHENK , Harpreet SINGH
IPC分类号： C07K14/47 , A61K39/00 , C07K16/30 , C12N5/0783 , C07K14/725 , A61K45/06 , A61K35/17 , C12N15/115 , A61P35/02 , A61P35/00 , C07K14/74 , C07K16/28
CPC分类号： C07K14/4748 , A61K39/0011 , C07K16/3053 , C07K16/30 , C07K16/3015 , C07K16/3023 , C12N5/0636 , C07K14/7051 , C07K16/303 , A61K39/001193 , A61K45/06 , A61K35/17 , C07K16/3069 , C12N15/115 , C07K16/3046 , A61P35/02 , A61K39/001186 , C07K16/3038 , C07K16/3061 , A61P35/00 , C07K14/70539 , C07K16/2833 , C07K2319/00 , C12N2310/16
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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3.发明公开公开(公告)号：US20230227517A1
公开(公告)日：2023-07-20
申请号：US18158734
申请日：2023-01-24
发明人： Andrea MAHR , Toni WEINSCHENK , Helen HOERZER , Oliver SCHOOR , Jens FRITSCHE , Harpreet SINGH
IPC分类号： C07K14/47 , A61K35/17 , A61K39/00 , C07K7/06 , C07K7/08 , C07K14/705 , C07K14/74 , C07K14/82 , C07K16/18 , C07K16/28 , C07K16/30 , C07K16/32 , C12N5/0783 , C12N15/115 , C12P21/02 , C12Q1/6881 , C12Q1/6886 , G01N33/569 , G01N33/574
CPC分类号： C07K14/4748 , A61K35/17 , A61K39/0011 , C07K7/06 , C07K7/08 , C07K14/4705 , C07K14/4738 , C07K14/705 , C07K14/70539 , C07K14/82 , C07K16/18 , C07K16/28 , C07K16/2833 , C07K16/30 , C07K16/3015 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K16/3046 , C07K16/3053 , C07K16/3069 , C07K16/32 , C12N5/0636 , C12N15/115 , C12P21/02 , C12Q1/6881 , C12Q1/6886 , G01N33/56977 , G01N33/57449 , G01N33/57492 , A61K38/00
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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公开(公告)号：US20230203114A1
公开(公告)日：2023-06-29
申请号：US18063430
申请日：2022-12-08
发明人： Oliver SCHOOR , Andrea MAHR , Toni WEINSCHENK , Anita WIEBE , Jens FRITSCHE , Harpreet SINGH
IPC分类号： C07K14/47 , A61P35/00 , A61K39/00 , C07K14/74 , C07K16/28 , C12N5/0783 , C12N15/113 , C07K14/725 , C07K16/30
CPC分类号： C07K14/4748 , A61P35/00 , A61K39/001154 , A61K39/0011 , C07K14/70539 , C07K16/2833 , C12N5/0636 , C12N15/1138 , C07K14/7051 , C07K16/3046 , C07K16/3076 , C07K2317/34 , C12N2501/50 , C12N2310/16 , A61K2039/5154 , A61K2039/5158
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T-cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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公开(公告)号：US20230192791A1
公开(公告)日：2023-06-22
申请号：US17934663
申请日：2022-09-23
发明人： Colette SONG , Oliver SCHOOR , Jens FRITSCHE , Toni WEINSCHENK , Harpreet SINGH
IPC分类号： C07K14/47 , C07K16/28 , C12N15/115 , G01N33/574 , C07K14/54 , C07K7/06 , C12N5/0783 , C07K16/30 , A61K39/00 , C07K14/74 , A61P35/00 , C07K14/725 , C12N15/10 , A61K35/17
CPC分类号： C07K14/4748 , C07K16/2818 , C12N15/115 , G01N33/57492 , C07K14/5434 , C07K7/06 , C12N5/0638 , C07K16/30 , A61K39/0011 , C07K14/70539 , A61P35/00 , A61K39/001102 , C07K14/7051 , C12N15/1062 , A61K35/17 , A61K2039/572 , C07K2319/00 , A61K2039/5158 , C12N2501/50 , A61K38/00
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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公开(公告)号：US20230088845A1
公开(公告)日：2023-03-23
申请号：US18056858
申请日：2022-11-18
发明人： Oliver SCHOOR , Andrea MAHR , Toni WEINSCHENK , Anita WIEBE , Jens FRITSCHE , Harpreet SINGH
IPC分类号： C07K14/47 , A61P35/00 , A61K39/00 , C07K14/74 , C07K16/28 , C12N5/0783 , C12N15/113 , C07K14/725 , C07K16/30
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T-cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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公开(公告)号：US20230086855A1
公开(公告)日：2023-03-23
申请号：US18056887
申请日：2022-11-18
发明人： Oliver SCHOOR , Andrea MAHR , Toni WEINSCHENK , Anita WIEBE , Jens FRITSCHE , Harpreet SINGH
IPC分类号： C07K14/47 , A61P35/00 , A61K39/00 , C07K14/74 , C07K16/28 , C12N5/0783 , C12N15/113 , C07K14/725 , C07K16/30
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T-cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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公开(公告)号：US20230043654A1
公开(公告)日：2023-02-09
申请号：US17933298
申请日：2022-09-19
发明人： Colette SONG , Oliver SCHOOR , Jens FRITSCHE , Toni WEINSCHENK , Harpreet SINGH
IPC分类号： C07K14/47 , C07K7/06 , C07K14/725 , A61K35/17 , C07K14/74 , C07K16/30 , C07K16/28 , C12N15/10 , A61K39/00 , C07K14/54 , G01N33/574 , C12N5/0783 , C12N15/115 , A61P35/00
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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公开(公告)号：US20230012265A1
公开(公告)日：2023-01-12
申请号：US17478041
申请日：2021-09-17
发明人： Colette SONG , Heiko SCHUSTER , Daniel Johannes KOWALEWSKI , Oliver SCHOOR , Jens FRITSCHE , Toni WEINSCHENK , Harpreet SINGH
IPC分类号： C07K14/47 , A61K35/17 , A61K39/00 , C07K14/725 , C07K14/74 , C07K16/18 , C12N5/0783 , C12Q1/6886
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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公开(公告)号：US20230002461A1
公开(公告)日：2023-01-05
申请号：US17886752
申请日：2022-08-12
发明人： Colette SONG , Oliver SCHOOR , Jens FRITSCHE , Toni WEINSCHENK , Harpreet SINGH
IPC分类号： C07K14/47 , C12N15/10 , C07K16/30 , C07K7/06 , G01N33/574 , A61K35/17 , C12N15/115 , C07K14/54 , C07K14/74 , C07K16/28 , A61K39/00 , C07K14/725 , C12N5/0783 , A61P35/00
摘要： The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
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