公开(公告)号：US10913975B2

公开(公告)日：2021-02-09

申请号：US15747670

申请日：2016-07-21

申请人： ILLUMINA, INC.

发明人： Alex So ,  Li Liu ,  Min-Jui Richard Shen ,  Neeraj Salathia ,  Kathryn M. Stephens ,  Anne Jager ,  Timothy Wilson ,  Justin Fullerton ,  Sean M. Ramirez ,  Shannon Kaplan ,  Rigo Pantoja ,  Bala Murali Venkatesan ,  Steven Modiano

IPC分类号： C12Q1/68 ,  C12Q1/6837 ,  C12Q1/6874 ,  C12Q1/6816 ,  C12Q1/6855

摘要： Presented are methods and compositions for spatial detection and analysis of nucleic acids in a tissue sample. The methods can enable the characterization of transcriptomes and/or genomic variations in tissues while preserving spatial information about the tissue.

公开(公告)号：US20210198659A1

公开(公告)日：2021-07-01

申请号：US17197836

申请日：2021-03-10

申请人： Illumina, Inc.

发明人： Neeraj Salathia ,  Jian-Bing Fan ,  Fiona Kaper ,  Gordon M. Cann ,  Arash Jamshidi ,  Alex Aravanis

IPC分类号： C12N15/10 ,  C12Q1/6869 ,  C12Q1/6853 ,  C12Q1/6806

摘要： Presented herein are methods and compositions for multiplexed single cell gene expression analysis. Some methods and compositions include the use of droplets and/or beads bearing unique barcodes such as unique molecular barcodes (UMI).

公开(公告)号：US20210130885A1

公开(公告)日：2021-05-06

申请号：US17145846

申请日：2021-01-11

申请人： ILLUMINA, INC.

发明人： Alex So ,  Li Liu ,  Min-Jui Richard Shen ,  Neeraj Salathia ,  Kathryn M. Stephens ,  Anne Jager ,  Timothy Wilson ,  Justin Fullerton ,  Sean M. Ramirez ,  Shannon Kaplan ,  Rigo Pantoja ,  Bala Murali Venkatesan ,  Steven Modiano

IPC分类号： C12Q1/6837 ,  C12Q1/6874 ,  C12Q1/6816 ,  C12Q1/6855

摘要： Presented are methods and compositions for spatial detection and analysis of nucleic acids in a tissue sample. The methods can enable the characterization of transcriptomes and/or genomic variations in tissues while preserving spatial information about the tissue.

公开(公告)号：US10975371B2

公开(公告)日：2021-04-13

申请号：US14855207

申请日：2015-09-15

申请人： ILLUMINA, INC.

发明人： Neeraj Salathia ,  Jian-Bing Fan ,  Fiona Kaper ,  Gordon M. Cann ,  Arash Jamshidi ,  Alex Aravanis

IPC分类号： C12N15/10 ,  C12Q1/6869 ,  C12Q1/6853 ,  C12Q1/6806

摘要： Presented herein are methods and compositions for multiplexed single cell gene expression analysis. Some methods and compositions include the use of droplets and/or beads bearing unique barcodes such as unique molecular barcodes (UMI).