公开(公告)号：US20240076438A1

公开(公告)日：2024-03-07

申请号：US18364242

申请日：2023-08-02

Applicant: Hyalex Orthopaedics, Inc.

Inventor： Lampros Kourtis ,  David Myung ,  Daniel Chang ,  Bing Yu ,  Timothy Sun ,  Michael J. Jaasma ,  Vernon Hartdegen

IPC: C08G18/62 ,  A61F2/30 ,  A61K47/32 ,  A61L24/00 ,  A61L24/04 ,  A61L24/06 ,  A61M5/19 ,  B65D85/00 ,  C08G18/32 ,  C08G18/48 ,  C08G18/65 ,  C08G18/67 ,  C08G18/72 ,  C08G81/02 ,  C08L33/08 ,  C08L33/12 ,  C09J4/06 ,  C09J133/14 ,  C09J135/02 ,  F01D5/08 ,  F01D11/00 ,  F01D11/02

CPC classification number: C08G18/6229 ,  A61F2/30 ,  A61K47/32 ,  A61L24/001 ,  A61L24/0015 ,  A61L24/043 ,  A61L24/06 ,  A61M5/19 ,  B65D85/70 ,  C08G18/3206 ,  C08G18/4854 ,  C08G18/6511 ,  C08G18/6705 ,  C08G18/728 ,  C08G81/024 ,  C08L33/08 ,  C08L33/12 ,  C09J4/06 ,  C09J133/14 ,  C09J135/02 ,  F01D5/082 ,  F01D11/001 ,  F01D11/025 ,  A61B17/56 ,  A61L2300/406 ,  A61L2430/24 ,  F05D2240/57 ,  F05D2260/14

Abstract: Methods, compositions, and kits for adhering polymers and other materials to another material, and in particular to bone or bone-like structures or surfaces. A composition of matter includes a urethane dimethacrylate-methyl methacrylate copolymer with a plurality of first polymer regions based on urethane dimethacrylate and a plurality of second polymer regions based on methyl methacrylate. The method includes placing an orthopedic joint implant having an attachment surface in a joint space, applying a first non-urethane-containing precursor, a second urethane-containing precursor, and a initiator to the attachment surface; contacting the first and second precursors and the initiator with the joint surface; and copolymerizing the first and second precursors and forming an adhesive copolymer and attaching the implant to the joint.

公开(公告)号：US10519270B2

公开(公告)日：2019-12-31

申请号：US15668547

申请日：2017-08-03

Applicant: Hyalex Orthopaedics, Inc.

Inventor： Lampros Kourtis ,  David Myung ,  Daniel Chang ,  Bing Yu ,  Timothy Sun ,  Michael J. Jaasma ,  Vernon Hartdegen

IPC: A61F2/30 ,  A61K47/32 ,  C08G18/62 ,  A61M5/19 ,  B65D85/00 ,  C09J133/14 ,  A61L24/06 ,  C08G18/48 ,  C08G18/65 ,  C08G18/67 ,  C08G18/32 ,  C09J4/06 ,  C09J135/02 ,  A61L24/00 ,  A61L24/04 ,  C08G18/72 ,  C08G81/02 ,  C08L33/08 ,  C08L33/12 ,  F01D5/08 ,  F01D11/00 ,  F01D11/02 ,  A61B17/56

Abstract: Methods, compositions, and kits for adhering polymers and other materials to another material, and in particular to bone or bone-like structures or surfaces. A composition of matter includes a urethane dimethacrylate-methyl methacrylate copolymer with a plurality of first polymer regions based on urethane dimethacrylate and a plurality of second polymer regions based on methyl methacrylate. The method includes placing an orthopedic joint implant having an attachment surface in a joint space, applying a first non-urethane-containing precursor, a second urethane-containing precursor, and a initiator to the attachment surface; contacting the first and second precursors and the initiator with the joint surface; and copolymerizing the first and second precursors and forming an adhesive copolymer and attaching the implant to the joint.

公开(公告)号：US09750842B2

公开(公告)日：2017-09-05

申请号：US14877884

申请日：2015-10-07

Applicant: HYALEX ORTHOPAEDICS, INC.

Inventor： Lampros Kourtis ,  David Myung ,  Daniel Chang ,  Bing Yu ,  Timothy Sun ,  Michael J. Jaasma ,  Vernon Hartdegen

IPC: A61L24/06 ,  A61F2/30 ,  A61K47/32 ,  A61M5/19 ,  B65D85/00 ,  C09J133/14 ,  C08G18/48 ,  C08G18/65 ,  C08G18/67 ,  C08G18/32 ,  C09J4/06 ,  C09J135/02 ,  A61L24/00 ,  A61L24/04

CPC classification number: C08G18/6229 ,  A61B17/56 ,  A61F2/30 ,  A61K47/32 ,  A61L24/001 ,  A61L24/0015 ,  A61L24/043 ,  A61L24/06 ,  A61L2300/406 ,  A61L2430/24 ,  A61M5/19 ,  B65D85/70 ,  C08G18/3206 ,  C08G18/4854 ,  C08G18/6511 ,  C08G18/6705 ,  C08G18/728 ,  C08G81/024 ,  C08L33/08 ,  C08L33/12 ,  C09J4/06 ,  C09J133/14 ,  C09J135/02 ,  C08F2220/343 ,  C08F220/14

Abstract: Methods, compositions, and kits for adhering polymers and other materials to another material, and in particular to bone or bone-like structures or surfaces. A composition of matter includes a urethane dimethacrylate-methyl methacrylate copolymer with a plurality of first polymer regions based on urethane dimethacrylate and a plurality of second polymer regions based on methyl methacrylate. The method includes placing an orthopedic joint implant having an attachment surface in a joint space, applying a first non-urethane-containing precursor, a second urethane-containing precursor, and a initiator to the attachment surface; contacting the first and second precursors and the initiator with the joint surface; and copolymerizing the first and second precursors and forming an adhesive copolymer and attaching the implant to the joint.

公开(公告)号：US12139574B2

公开(公告)日：2024-11-12

申请号：US18364242

申请日：2023-08-02

Applicant: Hyalex Orthopaedics, Inc.

Inventor： Lampros Kourtis ,  David Myung ,  Daniel Chang ,  Bing Yu ,  Timothy Sun ,  Michael J. Jaasma ,  Vernon Hartdegen

IPC: A61F2/30 ,  A61K47/32 ,  A61L24/00 ,  A61L24/04 ,  A61L24/06 ,  A61M5/19 ,  B65D85/00 ,  C08G18/32 ,  C08G18/48 ,  C08G18/62 ,  C08G18/65 ,  C08G18/67 ,  C08G18/72 ,  C08G81/02 ,  C08L33/08 ,  C08L33/12 ,  C09J4/06 ,  C09J133/14 ,  C09J135/02 ,  F01D5/08 ,  F01D11/00 ,  F01D11/02 ,  A61B17/56

Abstract: Methods, compositions, and kits for adhering polymers and other materials to another material, and in particular to bone or bone-like structures or surfaces. A composition of matter includes a urethane dimethacrylate-methyl methacrylate copolymer with a plurality of first polymer regions based on urethane dimethacrylate and a plurality of second polymer regions based on methyl methacrylate. The method includes placing an orthopedic joint implant having an attachment surface in a joint space, applying a first non-urethane-containing precursor, a second urethane-containing precursor, and a initiator to the attachment surface; contacting the first and second precursors and the initiator with the joint surface; and copolymerizing the first and second precursors and forming an adhesive copolymer and attaching the implant to the joint.

公开(公告)号：US11760830B2

公开(公告)日：2023-09-19

申请号：US17246819

申请日：2021-05-03

Applicant: Hyalex Orthopaedics, Inc.

Inventor： Lampros Kourtis ,  David Myung ,  Daniel Chang ,  Bing Yu ,  Timothy Sun ,  Michael J. Jaasma ,  Vernon Hartdegen

IPC: A61F2/30 ,  A61K47/32 ,  C08G18/62 ,  C08G18/48 ,  C08G18/65 ,  C08G18/67 ,  C08G18/32 ,  C09J4/06 ,  C09J135/02 ,  C08L33/08 ,  C08L33/12 ,  F01D5/08 ,  F01D11/02 ,  F01D11/00 ,  A61M5/19 ,  B65D85/00 ,  C09J133/14 ,  A61L24/06 ,  A61L24/00 ,  A61L24/04 ,  C08G18/72 ,  C08G81/02 ,  A61B17/56

CPC classification number: C08G18/6229 ,  A61F2/30 ,  A61K47/32 ,  A61L24/001 ,  A61L24/0015 ,  A61L24/043 ,  A61L24/06 ,  A61M5/19 ,  B65D85/70 ,  C08G18/3206 ,  C08G18/4854 ,  C08G18/6511 ,  C08G18/6705 ,  C08G18/728 ,  C08G81/024 ,  C08L33/08 ,  C08L33/12 ,  C09J4/06 ,  C09J133/14 ,  C09J135/02 ,  F01D5/082 ,  F01D11/001 ,  F01D11/025 ,  A61B17/56 ,  A61L2300/406 ,  A61L2430/24 ,  F05D2240/57 ,  F05D2260/14 ,  A61L24/06 ,  C08L33/12 ,  C09J133/14 ,  C08L33/08 ,  C09J135/02 ,  C08L33/12 ,  C08F220/343 ,  C08F220/14

Abstract: Methods, compositions, and kits for adhering polymers and other materials to another material, and in particular to bone or bone-like structures or surfaces. A composition of matter includes a urethane dimethacrylate-methyl methacrylate copolymer with a plurality of first polymer regions based on urethane dimethacrylate and a plurality of second polymer regions based on methyl methacrylate. The method includes placing an orthopedic joint implant having an attachment surface in a joint space, applying a first non-urethane-containing precursor, a second urethane-containing precursor, and a initiator to the attachment surface; contacting the first and second precursors and the initiator with the joint surface; and copolymerizing the first and second precursors and forming an adhesive copolymer and attaching the implant to the joint.

公开(公告)号：US11015016B2

公开(公告)日：2021-05-25

申请号：US16688351

申请日：2019-11-19

Applicant: Hyalex Orthopaedics, Inc.

Inventor： Lampros Kourtis ,  David Myung ,  Daniel Chang ,  Bing Yu ,  Timothy Sun ,  Michael J. Jaasma ,  Vernon Hartdegen

IPC: A61F2/30 ,  A61K47/32 ,  C08G18/62 ,  C08G18/48 ,  C08G18/65 ,  C08G18/67 ,  C08G18/32 ,  C09J4/06 ,  C09J135/02 ,  C08L33/08 ,  C08L33/12 ,  F01D5/08 ,  F01D11/02 ,  F01D11/00 ,  A61M5/19 ,  B65D85/00 ,  C09J133/14 ,  A61L24/06 ,  A61L24/00 ,  A61L24/04 ,  C08G18/72 ,  C08G81/02 ,  A61B17/56

Abstract: Methods, compositions, and kits for adhering polymers and other materials to another material, and in particular to bone or bone-like structures or surfaces. A composition of matter includes a urethane dimethacrylate-methyl methacrylate copolymer with a plurality of first polymer regions based on urethane dimethacrylate and a plurality of second polymer regions based on methyl methacrylate. The method includes placing an orthopedic joint implant having an attachment surface in a joint space, applying a first non-urethane-containing precursor, a second urethane-containing precursor, and a initiator to the attachment surface; contacting the first and second precursors and the initiator with the joint surface; and copolymerizing the first and second precursors and forming an adhesive copolymer and attaching the implant to the joint.