公开(公告)号：US20170057906A1

公开(公告)日：2017-03-02

申请号：US15352903

申请日：2016-11-16

Applicant: Hong Kong Baptist University

Inventor： Hongjie ZHANG ,  Siu Wai TSANG ,  Yu ZHU

IPC: C07C69/80 ,  C07C43/205 ,  C07C43/215 ,  C07C69/34 ,  A61K8/34 ,  A61K8/37 ,  A61K8/33 ,  A61Q19/02 ,  A61Q17/04 ,  C07C39/21 ,  C07C69/736 ,  C07C69/753

CPC classification number: A61K8/347 ,  A61K8/33 ,  A61K8/37 ,  A61K9/0053 ,  A61K31/05 ,  A61K31/085 ,  A61K31/09 ,  A61Q17/04 ,  A61Q19/02 ,  C07C37/003 ,  C07C39/15 ,  C07C39/16 ,  C07C39/21 ,  C07C43/2055 ,  C07C43/215 ,  C07C43/23 ,  C07C69/34 ,  C07C69/736 ,  C07C69/753 ,  C07C2601/08

Abstract: A skin-protection composition is shown that comprises stilbenoid(s) and/or stilbenoid-containing extract(s) obtained from Dendrobium plants, such as Dendrobium officinale and Dendrobium nobile for the management of melanogenesis, skin-darkening and skin-aging. More particularly, the usage of Dendrobium ingredients and stilbenoids is shown to reduce the formation of melanin in melanocytes. The usage of Dendrobium ingredients and stilbenoids is also shown to reduce the generation of reactive oxygen species and oxidative free radicals. The use of Dendrobium-derived extracts or ingredients or stilbenoids is shown in the formulation of skin-protection, skin-whitening and/or anti-skin aging products.

Abstract translation: 显示出一种皮肤保护组合物，其包含从石斛属植物获得的含有萜烯和/或芪类的提取物，例如石斛兰和石斛石斛用于管理黑素生成，皮肤变暗和皮肤老化。 更具体地说，石斛成分和芪类化合物的使用被证明可以减少黑素细胞中黑色素的形成。 还显示石斛粉成分和芪类化合物的使用可以减少活性氧和氧化自由基的产生。 在皮肤保护，皮肤美白和/或抗皮肤衰老产品的配方中显示了使用石斛衍生的提取物或成分或芪类化合物。

公开(公告)号：US20240076299A1

公开(公告)日：2024-03-07

申请号：US18258224

申请日：2021-12-07

Applicant: Hong Kong Baptist University

Inventor： Hongjie ZHANG ,  Yu ZHU ,  Nga Yi TSANG ,  Yang ZHAO

IPC: C07D493/04 ,  A61K31/365 ,  A61K36/19 ,  A61P31/14 ,  A61P31/16 ,  A61P31/18 ,  C07D407/14 ,  C07F7/18

CPC classification number: C07D493/04 ,  A61K31/365 ,  A61K36/19 ,  A61P31/14 ,  A61P31/16 ,  A61P31/18 ,  C07D407/14 ,  C07F7/1804

Abstract: Provided herein are tuberculatin analogs that are useful as antivirals, such as anti-HIV, anti-coronaviral, anti-Ebola viral, and anti-influenza viral agents and methods of use thereof.

公开(公告)号：US20180228709A1

公开(公告)日：2018-08-16

申请号：US15922919

申请日：2018-03-16

Applicant: Hong Kong Baptist University

Inventor： Hongjie ZHANG ,  Siu Wai TSANG ,  Yu ZHU

IPC: A61K8/34 ,  C07C39/15 ,  A61K8/37 ,  A61K8/33 ,  A61Q19/02 ,  A61Q17/04 ,  A61K31/09 ,  C07C43/205 ,  C07C43/215 ,  C07C69/34 ,  C07C69/753 ,  C07C39/21 ,  C07C69/736

CPC classification number: A61K8/347 ,  A61K8/33 ,  A61K8/37 ,  A61K31/05 ,  A61K31/085 ,  A61K31/09 ,  A61Q17/04 ,  A61Q19/02 ,  C07C39/16 ,  C07C39/21 ,  C07C43/2055 ,  C07C43/215 ,  C07C43/23 ,  C07C69/34 ,  C07C69/736 ,  C07C69/753 ,  C07C2601/08

Abstract: The present invention relates to a skin-protection composition that comprises stilbenoid(s) and/or stilbenoid-containing extract(s) obtained from Dendrobium plants, such as Dendrobium officinale and Dendrobium nobile for the management of melanogenesis, skin-darkening and skin-aging. More particularly, it relates to the usage of Dendrobium ingredients and stilbenoids to reduce the formation of melanin in melanocytes. It also relates to the usage of Dendrobium ingredients and stilbenoids to reduce the generation of reactive oxygen species and oxidative free radicals. This invention relates to the use Dendrobium-derived extracts or ingredients or stilbenoids in the formulation of skin-protection, skin-whitening and/or anti-skin aging products.