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公开(公告)号：US20250138042A1
公开(公告)日：2025-05-01
申请号：US18835490
申请日：2022-12-21
Applicant: Hitachi High-Tech Corporation
Inventor： Kyohei MATSUDA , Masaaki HIRANO , Eiichiro TAKADA , Yuto FUKUYAMA , Chie YABUTANI , Masafumi SHIMADA
IPC: G01N35/10
Abstract: Provided is an automatic analyzer and a control method thereof that are capable of preventing liquid leakage when a dispensing probe that aspirated air and a liquid in order rises. The automatic analyzer for analyzing a sample includes: a dispensing unit configured to dispense the sample and/or a reagent; and a control unit configured to control the dispensing unit. When a dispensing probe provided in the dispensing unit rises after aspirating air and a liquid in order, the control unit aspirates an amount of outside air corresponding to a length of expansion of the air through a tip of the dispensing probe.
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公开(公告)号：US20230333133A1
公开(公告)日：2023-10-19
申请号：US18027183
申请日：2021-08-26
Applicant: HITACHI HIGH-TECH CORPORATION
Inventor： Kazuhiro NODA , Koshin HAMASAKI , Masayuki KUWABARA , Eiichiro TAKADA
IPC: G01N35/10
CPC classification number: G01N35/1016 , G01N35/1065 , G01N2035/103 , G01N2035/1076
Abstract: The purpose of the present invention is to provide an automatic analysis device capable of ensuring accuracy in a wide range of a pipetting amount without changing the rotation/vertical speed of a sampling arm and the aspiration speed of a pump. The automatic analysis device according to the present invention, which is an automatic analysis device for analyzing a target substance included in a sample, is characterized by comprising: a detection unit that analyzes the sample; and a probe that pipettes a liquid, wherein the probe changes the number of aspiration by which the liquid is aspirated into the probe according to the pipetting amount by which the probe pipettes the liquid.
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公开(公告)号：US20230236056A1
公开(公告)日：2023-07-27
申请号：US17919820
申请日：2021-02-02
Applicant: HITACHI HIGH-TECH CORPORATION
Inventor： Masaaki HIRANO , Masafumi SHIMADA , Eiichiro TAKADA , Akihisa MAKINO
IPC: G01F23/263 , G01N35/10
CPC classification number: G01F23/266 , G01N35/1016 , G01N2035/1025
Abstract: An object of the present invention is to provide a dispensing device capable of preventing bubbles from jumping out of a nozzle and realizing highly accurate dispensing even though the nozzle is moved at a high speed toward a liquid level and is decelerated and stopped at a high acceleration. The dispensing device according to the present invention starts suction of a liquid in a period from when a nozzle starts to be lowered toward a liquid level of the liquid to when an end portion of the nozzle comes into contact with the liquid level of the liquid and the lowering of the nozzle is stopped (see FIG. 6).
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公开(公告)号：US20250035662A1
公开(公告)日：2025-01-30
申请号：US18706851
申请日：2022-11-07
Applicant: Hitachi High-Tech Corporation
Inventor： Kazuhiro NODA , Eiichiro TAKADA , Koshin HAMASAKI , Kenichi NISHIGAKI
IPC: G01N35/10
Abstract: The present invention provides an automated analysis device capable of detecting whether or not a plurality of fluid control valves included in the automated analysis device operate normally at low cost. The automated analysis device according to the present invention includes a plurality of fluid control valves placed in a flow path, a pressure sensor (112) which measures pressure in the flow path, a liquid level detection element (103c) which detects a position of a liquid level of a liquid discharged by a discharge nozzle (120, 124), and a control unit (100). One or more of the fluid control valves act as a first fluid control valve (108, 110) connected to the pressure sensor (112) through the flow path. One or more of the fluid control valves act as a second fluid control valve (115, 118, 123) connected to the discharge nozzle (120, 124) through the flow path. The control unit (100) detects whether the first fluid control valve (108, 110) has normally operated based on the pressure value measured by the pressure sensor (112), and detects whether the second fluid control valve (115, 118, 123) has normally operated based on the position of the liquid level detected by the liquid level detection element (103c).
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公开(公告)号：US20240369585A1
公开(公告)日：2024-11-07
申请号：US18683965
申请日：2022-08-08
Applicant: HITACHI HIGH-TECH CORPORATION , F. HOFFMANN-LA ROCHE AG
Inventor： Yuki MIYADA , Eiichiro TAKADA , Koshin HAMASAKI , Akira JOJI , Elisabeth FOESTER , Christoph RUTZ
Abstract: Provided are an automatic analyzer that can decrease waiting time for a user and reduce running costs as compared with in the past and an operation method for the automatic analyzer. The analyzer includes: a first mechanism group that is used only in analysis for biochemical items; a second mechanism group that is used only in analysis for immunological items; a common mechanism group that is used in analysis for both biochemical items and immunological items; and a control part that activates the second mechanism group and common mechanism group without activating the first mechanism group when analysis for biochemical items is not required, and activates the first mechanism group and common mechanism group without activating the second mechanism group when analysis for immunological items is not required.
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Patent Agency Ranking
公开(公告)号：US20240012019A1
公开(公告)日：2024-01-11
申请号：US18036522
申请日：2021-10-15
Applicant: Hitachi High-Tech Corporation
Inventor： Yuka MIYAKE , Koshin HAMASAKI , Eiichiro TAKADA
IPC: G01N35/10
CPC classification number: G01N35/1009 , G01N35/1002 , G01N35/1004
Abstract: An automatic analyzer performs a dispensing operation with high throughput while reducing a risk of carry-over of a reagent that includes first and second dispensing operations. The second dispensing operation includes a first procedure of aspirating a sample accommodated by a dispensing nozzle, a second procedure of discharging the aspirated sample to a first reaction container, a third procedure in which a cleaning tank cleans an inner side and an outer side of the dispensing nozzle after the second procedure, a fourth procedure of aspirating the reagent accommodated in a reagent container after the third procedure, a fifth procedure B5 in which the cleaning tank cleans the outer side of the dispensing nozzle after the fourth procedure, a sixth procedure of aspirating the sample accommodated in the first reaction container after the fifth procedure, and a seventh procedure of discharging the reagent and the sample to a second reaction container.
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公开(公告)号：US20220397582A1
公开(公告)日：2022-12-15
申请号：US17775409
申请日：2020-10-21
Applicant: Hitachi High-Tech Corporation
Inventor： Mariko MIYAZAKI , Nobuhiro TSUKADA , Kazuhiro NODA , Eiichiro TAKADA , Yuka MIYAKE
IPC: G01N35/02
Abstract: An automatic analysis device improves the uniformity of a mixed liquid by noise agitation by a dispensing mechanism. The dispensing mechanism agitates a mixed liquid by suctioning the mixed liquid into a reaction vessel by a nozzle and then re-discharging the suctioned mixed liquid into the reaction vessel. When the mixed liquid is re-discharged into the reaction vessel, the nozzle is moved upward at a speed higher than a speed at which the liquid surface of the mixed liquid rises due to the re-discharging of the mixed liquid from the nozzle during a first period and lowers the speed of moving the nozzle upward than the speed during the first period while maintaining or reducing the speed at which the liquid surface of the mixed liquid rises due to re-discharging of the mixed liquid from the nozzle during a second period following the first period.
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公开(公告)号：US20210349112A1
公开(公告)日：2021-11-11
申请号：US17278146
申请日：2020-01-20
Inventor： Koshin HAMASAKI , Eiichiro TAKADA , Shigeki MATSUBARA , Tatsuya FUKUGAKI , Stefan KOBEL , Ralf KRAUS
Abstract: There is provided an automatic analyzer that can reduce a cleaning agent used for cleaning a puddle configured to stir a reagent including a fine particle. An automatic analyzer including a reagent container configured to accommodate a reagent including a fine particle, a puddle configured to stir the reagent, and a cleaning unit configured to immerse the puddle in a cleaning vessel reserving a cleaning agent. The automatic analyzer further includes a determining unit configured to determine whether to totally replace the cleaning agent based on a score computed using a number of times of cleaning the puddle having stirred the reagent in the cleaning unit and a remaining amount of the reagent. When the determining unit determines that the cleaning agent is totally replaced, the cleaning unit displays, on a screen, a notification of total replacement of the cleaning agent, or recommendation of the total replacement.
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公开(公告)号：US20250035661A1
公开(公告)日：2025-01-30
申请号：US18706775
申请日：2022-11-02
Applicant: Hitachi High-Tech Corporation
Inventor： Takeru CHUMAN , Eiichiro TAKADA
IPC: G01N35/10
Abstract: An object of the invention is to provide a low-cost automatic analyzer without reducing a throughput. A cleaning tank is arranged such that a detection timing for a dispensing tip occurs when the dispensing tip moves to the cleaning tank, and a sensor that monitors the cleaning tank is arranged. By performing an operation of returning to the cleaning tank after an operation in a sample discharge area, the dispensing tip can be detected at all timings at which the dispensing tip needs to be confirmed during normal analysis by one sensor that monitors the cleaning tank.
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公开(公告)号：US20240359183A1
公开(公告)日：2024-10-31
申请号：US18571791
申请日：2022-06-23
Applicant: Hitachi High-Tech Corporation
Inventor： Norihiro HAYASHIDA , Yuya MATSUOKA , Eiichiro TAKADA
CPC classification number: B01L3/5082 , B01L9/06 , G01N21/0332 , G01N21/253 , G01N21/272 , B01L2200/025 , B01L2300/0609 , B01L2300/0803 , B01L2300/0832 , B01L2300/1805 , G01N2021/0325
Abstract: When a reaction solution in a reaction vessel is irradiated with light to measure an amount of transmitted light or the like, the reaction vessel rattles due to vibration and an optical axis is shifted. Therefore, a torsion coil spring for urging the reaction vessel is provided in a heat block having a plurality of reaction vessel placement holes on which the reaction vessel is mounted, the reaction vessel includes a protrusion on a part of a side surface, and when the reaction vessel is inserted in the hole, an arm of the torsion coil spring is operated so as to be retreated along the protrusion, and, when the reaction vessel is fitted in the hole, it urges the protrusion horizontally with a lower side in a vertical direction and urges the reaction vessel to press against the wall of the hole.
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