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    Heat developable light-sensitive material with development inhibitor releaser
    2.
    发明授权
    Heat developable light-sensitive material with development inhibitor releaser 失效
    具有显影抑制剂释放剂的热显影光敏材料

    公开(公告)号：US4678735A

    公开(公告)日：1987-07-07

    申请号：US774427

    申请日：1985-09-10

    申请人： Hiroshi Kitaguchi ,  Masatoshi Kato ,  Kozo Sato ,  Masasi Takeuchi ,  Masaaki Tsukase

    发明人： Hiroshi Kitaguchi ,  Masatoshi Kato ,  Kozo Sato ,  Masasi Takeuchi ,  Masaaki Tsukase

    IPC分类号： G03C7/305 ,  G03C8/40 ,  G03C5/54 ,  G03C1/34

    CPC分类号： G03C8/408 ,  G03C7/30511 ,  Y10S430/158 ,  Y10S430/161

    摘要： A heat developable light-sensitive material containing a compound represented by general formula (I) described below in a light-sensitive layer or an image receiving layer thereof: ##STR1## wherein X represents an atomic group necessary to complete a benzene ring or a naphthalene ring; R represents a group convertible to a hydroxy group or a dissociation form thereof at the time of heat development; Y represents an atomic group necessary to complete a 5-membered or 6-membered heterocyclic group containing at least one nitrogen atom; Q represents a hydrogen atom, an alkyl group, a substituted alkyl group, an aryl group, or a substituted aryl group; TIME represents a timing group; and n represents 0 or a positive integer. The heat developable light-sensitive material containing the compound represented by general formula (I), which is stable at room temperature and releases a development inhibitor to stop the development at the time of heat development, can provide a color image having a high S/N ratio and a high density.

    摘要翻译： 含有下述通式（I）表示的化合物的感光层或图像接收层的热显影性感光材料：其中X表示完成苯环所需的原子团 或萘环; R表示在热显影时可转化为羟基或其解离形式的基团; Y表示完成含有至少一个氮原子的5元或6元杂环基必需的原子团; Q表示氢原子，烷基，取代的烷基，芳基或取代的芳基; TIME代表一个时间组; n表示0或正整数。 含有由通式（I）表示的化合物在室温下稳定并释放显影抑制剂以在显影时停止显影的热显影光敏材料可以提供具有高S / N比和高密度。

    Method for formation of an image comprising a heating step
    4.
    发明授权
    Method for formation of an image comprising a heating step 失效
    用于形成包括加热步骤的图像的方法

    公开(公告)号：US4696887A

    公开(公告)日：1987-09-29

    申请号：US829032

    申请日：1986-02-13

    申请人： Kozo Sato ,  Hiroshi Kitaguchi ,  Masashi Takeuchi ,  Masaaki Tsukase ,  Masatoshi Kato

    发明人： Kozo Sato ,  Hiroshi Kitaguchi ,  Masashi Takeuchi ,  Masaaki Tsukase ,  Masatoshi Kato

    IPC分类号： G03C5/00 ,  G03C5/58 ,  G03C7/00 ,  G03C7/305 ,  G03C8/40 ,  G03C5/54 ,  G03C1/06 ,  G03C1/34 ,  G03C5/26

    CPC分类号： G03C8/408 ,  G03C7/305 ,  G03C8/4033 ,  Y10S430/158 ,  Y10S430/161

    摘要： A novel method for formation of an image comprising a heating step, comprising the heating carried out in the presence of a compound of general formula (I):X--SO.sub.2 (DI) (I)wherein X represents a reducing group capable of reducing a silver salt and capable of being oxidized by heating and in its oxidized state capable of releasing a compound represented by (DI)--SO.sub.2 NH.sub.2 by reaction with a nucleophilic agent; and (DI) represents a development inhibiting group capable of inhibiting the oxidation reduction reaction of the silver salt and a reducing aent.The compound of the formula (I) functions to inhibit development after a certain period of time from the beginning of heat development.The present method provides a stable image with reduced fog and image mottle.

    摘要翻译： 一种用于形成图像的新方法，包括加热步骤，其包括在通式（I）的化合物：X-SO 2（DI）（I）的存在下进行的加热，其中X表示可以还原的还原基团 银盐，能够通过与亲核剂反应而通过加热氧化并能够释放由（DI）-SO 2 NH 2表示的化合物的氧化态; 和（DI）表示能够抑制银盐的氧化还原反应和还原的显影抑制基团。 式（I）化合物起到抑制发育开始一段时间后的发育作用。 本方法提供了一种具有降低雾度和图像斑点的稳定图像。

    Image forming process including a heating step
    5.
    发明授权
    Image forming process including a heating step 失效
    图像形成处理包括加热步骤

    公开(公告)号：US4729936A

    公开(公告)日：1988-03-08

    申请号：US867176

    申请日：1986-05-27

    申请人： Hiroshi Kitaguchi ,  Kozo Sato ,  Masatoshi Kato

    发明人： Hiroshi Kitaguchi ,  Kozo Sato ,  Masatoshi Kato

    IPC分类号： G03C7/00 ,  C07D231/12 ,  G03C7/305 ,  G03C8/40 ,  G03C8/54 ,  G03C5/26 ,  G03C1/00 ,  G03C5/34 ,  G03C5/54

    CPC分类号： C07D231/12 ,  G03C7/30511 ,  G03C8/408 ,  Y10S430/156 ,  Y10S430/158 ,  Y10S430/16 ,  Y10S430/161

    摘要： An image forming process including a heating step is disclosed. The process comprises conducting said heating step in the presence of at least one compound represented by formula (I), (II), or (III). ##STR1## wherein R.sup.1 represents ##STR2## wherein R.sup.11 and R.sup.12 each represents a substituted or unsubstituted alkyl group, a substituted or unsubstituted cycloalkyl group, a substituted or unsubstituted alkenyl group, a substituted or unsubstituted aralkyl group, a substituted or unsubstituted aryl group, a substituted or unsubstituted heterocyclic group, a substituted or unsubstituted alkyloxy group, a substituted or unsubstituted aryloxy group, a substituted or unsubstituted alkylthio group, a substituted or unsubstituted arylthio group or a substituted or unsubstituted amino group; R.sup.11 and R.sup.12 together form a 5-membered or 6-membered ring; Q represents a hydrogen atom or a substituted or unsubstituted alkyl group, a substituted or unsubstituted cycloalkyl group, or a substituted or unsubstituted aryl group, or Q represents a group linked to the pyrazole ring, TIME or PUG either directly or through another atom to form a ring; TIME represents a timing group; PUG represents a photographically useful group; and n represents 0 or a positive integer.The image forming process provides for little variation in photographic characteristics even when there is a substantial variation in the heat-processing temperature.

    摘要翻译： 公开了一种包括加热步骤的图像形成过程。 该方法包括在至少一种由式（I），（II）或（III）表示的化合物的存在下进行所述加热步骤。 （Ⅰ）其中R1表示其中R11和R12各自表示取代或未取代的烷基，取代或未取代的环烷基，取代或未取代的烯基 取代或未取代的芳烷基，取代或未取代的芳基，取代或未取代的杂环基，取代或未取代的烷氧基，取代或未取代的芳氧基，取代或未取代的烷硫基，取代或未取代的芳硫基， 取代或未取代的氨基; R11和R12一起形成5元或6元环; Q表示氢原子或取代或未取代的烷基，取代或未取代的环烷基或取代或未取代的芳基，或Q表示与吡唑环连接的基团，TIME或PUG直接或通过另一个原子形成 戒指; TIME代表一个时间组; PUG代表一个摄影有用的组; n表示0或正整数。 即使在热处理温度存在显着变化的情况下，图像形成处理也提供了摄影特性的很小变化。

    Image-forming process involving heating step
    6.
    发明授权
    Image-forming process involving heating step 失效
    涉及加热步骤的成像工艺

    公开(公告)号：US4845018A

    公开(公告)日：1989-07-04

    申请号：US830031

    申请日：1986-02-18

    申请人： Kozo Sato ,  Hiroshi Kitaguchi ,  Masashi Takeuchi ,  Masaaki Tsukase ,  Masatoshi Kato

    发明人： Kozo Sato ,  Hiroshi Kitaguchi ,  Masashi Takeuchi ,  Masaaki Tsukase ,  Masatoshi Kato

    IPC分类号： G03C5/00 ,  G03C1/498 ,  G03C5/58 ,  G03C7/00 ,  G03C7/305 ,  G03C8/40

    CPC分类号： G03C7/30511 ,  G03C1/49845 ,  Y10S430/158 ,  Y10S430/161

    摘要： An image-forming process involving a heating step is disclosed, which comprises conducting the heating in the presence of a compound represented by the following general formula (I): ##STR1## wherein: R.sup.1 and R.sup.2, which may be the same or different, each represents a group selected from an aryl group, a substituted aryl group, a heterocyclic group, and a substituted heterocyclic group;R.sup.3 represents a hydrogen atom, an alkyl group, a substituted alkyl group, a cycloalkyl group, a substituted cycloalkyl group, an aralkyl group, a substituted aralkyl group, or a group selected from those which are referred to with respect to R.sup.1 and R.sup.2 ;R.sup.1, R.sup.2, and R.sup.3 may form a ring structure via a hydrocarbon chain, a hetero atom-containing hydrocarbon chain or a hetero atom, or may be directly bound to each other to form a ring structure; andPUG represents a photographically useful group.

    摘要翻译： 公开了涉及加热步骤的图像形成方法，其包括在由以下通式（I）表示的化合物存在下进行加热：其中：R1和R2可以相同 各自表示选自芳基，取代芳基，杂环基和取代的杂环基的基团; R3表示氢原子，烷基，取代的烷基，环烷基，取代的环烷基，芳烷基，取代的芳烷基或选自关于R 1和R 2的那些基团; R1，R2和R3可以通过烃链，含杂原子的烃链或杂原子形成环结构，或者可以彼此直接结合形成环结构; PUG代表摄影有用的组。

    Image forming method including heating step
    8.
    发明授权
    Image forming method including heating step 失效
    图像形成方法包括加热步骤

    公开(公告)号：US4678739A

    公开(公告)日：1987-07-07

    申请号：US810149

    申请日：1985-12-18

    申请人： Hiroshi Kitaguchi ,  Masashi Takeuchi ,  Kozo Sato ,  Masaaki Tsukase ,  Masatoshi Kato

    发明人： Hiroshi Kitaguchi ,  Masashi Takeuchi ,  Kozo Sato ,  Masaaki Tsukase ,  Masatoshi Kato

    IPC分类号： G03C1/52 ,  G03C1/06 ,  G03C1/498 ,  G03C5/00 ,  G03C7/00 ,  G03C8/40 ,  G03C5/54 ,  G03C1/34 ,  G03C5/26

    CPC分类号： G03C8/408 ,  G03C1/49845 ,  Y10S430/156 ,  Y10S430/158 ,  Y10S430/16

    摘要： A method for forming an image which has a step of heating an image-forming material in the presence of a compound represented by formula (I), whereby unevenness of image density and increase in fog due to fluctuation of development temperature, which have so far been caused in heat-developable photosensitive materials, can be prevented from occurring: ##STR1## wherein R represents a hydrogen atom, or a group selected from a class consisting of groups represented by formulae (A) to (C) ##STR2## wherein R.sup.11 and R.sup.12 each represents a substituted or unsubstituted alkyl group, a cycloalkyl group, a substituted or unsubstituted alkenyl group, an aralkyl group, a substituted or unsubstituted aryl group, a heterocyclic group, an alkyloxy group, an aryloxy group, an alkylthio group, an arylthio group, or a substituted or unsubstituted amino group, or R.sup.11 and R.sup.12 combine with each other to form a 5- or 6-membered ring;Q represents a hydrogen atom, an alkyl group, or an aryl group; TIME represents a timing group; PUG represents a photographically useful agent moiety; n represents 0 or an integer; and Z represents atoms forming a benzene ring.

    摘要翻译： 一种形成图像的方法，该方法具有在由式（I）表示的化合物存在下加热成像材料的步骤，从而由于显影温度的波动引起的图像浓度的不均匀性以及由于显影温度的波动引起的雾化的增加 （I）其中R表示氢原子或选自由式（A）至（C）表示的基团的基团的基团

    Anti-trypanosomiasis agent
    9.
    发明授权
    Anti-trypanosomiasis agent 有权
    抗锥虫病药

    公开(公告)号：US07795285B2

    公开(公告)日：2010-09-14

    申请号：US11576426

    申请日：2005-09-29

    申请人： Masataka Ihara ,  Kiyosei Takasu ,  Khanitha Pudhom ,  Hiroshi Kitaguchi ,  Masayuki Kawakami ,  Kozo Sato

    发明人： Masataka Ihara ,  Kiyosei Takasu ,  Khanitha Pudhom ,  Hiroshi Kitaguchi ,  Masayuki Kawakami ,  Kozo Sato

    IPC分类号： A01N43/78

    CPC分类号： C07D417/14 ,  A61K31/428 ,  A61K31/4439 ,  A61K31/4709 ,  Y02A50/414

    摘要： The present invention is to provide an anti-trypanosomiasis agent having a high selective toxicity, and high preventing or treating effect against trypanosomiasis, comprising a compound shown by the following general formula (1) as an active ingredient (wherein R1 and R2 each independently represents a hydrogen atom, halogen atom, hydroxyl group, oxygen atom, C1-5 alkyl group, C1-5 alkoxy group, C5-8 aryl group, C5-8 aryloxy group, C2-6 alkoxycarbonyl group or C2-6 alkylaminocarbonyl group, and may be bound to each other; R3, R4, and R5 each independently represents a C1-5 alkyl group or C5-8 aryl group; R6 and R7 each independently represents a hydrogen atom, halogen atom, hydroxyl group, oxygen atom, C1-8 alkyl group, C1-5 alkoxy group, C5-8 aryl group, C5-8 aryloxy group, or C2-6 alkoxycarbonyl group, and may be bound to each other; Y and Z each independently represents an atom group necessary to form a 5- or 6-membered heterocycle; m and n each represent 0 or 1; Q represents a physiologically acceptable anion; k represents an integer of 0 to 2, necessary to make the electric charge of the whole molecule 0).

    摘要翻译： 本发明提供具有高选择性毒性和对锥虫病的高预防或治疗作用的抗锥虫病药，其包含由以下通式（1）表示的化合物作为活性成分（其中R 1和R 2各自独立地表示 氢原子，卤素原子，羟基，氧原子，C 1-5烷基，C 1-5烷氧基，C 5-8芳基，C 5-8芳氧基，C 2-6烷氧基羰基或C 2-6烷基氨基羰基， 可以相互结合; R3，R4和R5各自独立地表示C1-5烷基或C5-8芳基; R6和R7各自独立地表示氢原子，卤素原子，羟基，氧原子，C1- 8个烷基，C 1-5烷氧基，C 5-8芳基，C 5-8芳氧基或C 2-6烷氧基羰基，并且可以彼此结合; Y和Z各自独立地表示形成 5-或6-元杂环; m和n各自表示0或1; Q表示物理 生理上可接受的阴离子 k表示0〜2的整数，使整个分子的电荷为0）。

    MEDICINAL COMPOSITION FOR PREVENTION OR TREATMENT OF PARASITIC PROTOZOAN INFECTION
    10.
    发明申请
    MEDICINAL COMPOSITION FOR PREVENTION OR TREATMENT OF PARASITIC PROTOZOAN INFECTION 有权
    用于预防或治疗PARASITIC PROTOZOAN感染的药物组合物

    公开(公告)号：US20100113789A1

    公开(公告)日：2010-05-06

    申请号：US11576429

    申请日：2005-09-30

    申请人： Masataka Ihara ,  Kiyosei Takasu ,  Khanitha Pudhom ,  Hiroshi Kitaguchi ,  Masayuki Kawakami ,  Kozo Sato

    发明人： Masataka Ihara ,  Kiyosei Takasu ,  Khanitha Pudhom ,  Hiroshi Kitaguchi ,  Masayuki Kawakami ,  Kozo Sato

    IPC分类号： C07D417/14

    CPC分类号： C07D277/84 ,  A61K31/427 ,  A61K31/428 ,  A61K31/4439 ,  A61K31/4709 ,  C07D277/64 ,  C07D417/14 ,  Y02A50/409 ,  Y02A50/411 ,  Y02A50/414

    摘要： The present invention is to provide a medicinal composition for preventing or treating parasitic protozoan infections, having a high selective toxicity against parasitic protozoan infection, and a superior preventive or treating effect. A medicinal composition for preventing or treating parasitic protozoan infections comprises a compound shown by the following general formula (1) as an active ingredient (wherein R represents an alkyl group, aryl group or heterocyclic group; A and B each independently represents a 5- or 6-membered ring containing at least one hetero atom, or a condensation ring wherein 1 or more 3- to 8-membered ring is condensed thereto; Y represents S, O, Se, or —NR1— (R1 represents an alkyl group, aryl group or heterocyclic group); L1, L2, L3, L4 and L5 each independently represents a methine group; Q represents a physiologically acceptable anion; k represents an integer of 0 to 2, necessary to make the electric charge of the whole molecule 0; p and q each represents an integer of 0 to 3, wherein the sum of p and q is 1 or more, and 6 or less.)

    摘要翻译： 本发明提供一种用于预防或治疗对寄生原虫感染具有高选择性毒性的寄生原虫感染的药物组合物，以及优异的预防或治疗效果。 用于预防或治疗寄生原生动物感染的药物组合物包含由以下通式（1）表示的化合物作为活性成分（其中R表示烷基，芳基或杂环基; A和B各自独立地表示5-或 含有至少一个杂原子的6元环或其中1个以上3〜8元环稠合的缩合环; Y表示S，O，Se或-NR1-（R1表示烷基，芳基 基团或杂环基）; L1，L2，L3，L4和L5各自独立地表示次甲基; Q表示生理上可接受的阴离子; k表示使整个分子0的电荷所必需的0至2的整数; p和q各自表示0〜3的整数，p和q的和为1以上6以下）