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8 条记录 (耗时 0.016 秒)

    NOVEL RNA SEQUENCE HAVING ANTI-TUMOUR ACTIVITY
    3.
    发明申请
    NOVEL RNA SEQUENCE HAVING ANTI-TUMOUR ACTIVITY 审中-公开
    具有抗肿瘤活性的新型RNA序列

    公开(公告)号：US20170073675A1

    公开(公告)日：2017-03-16

    申请号：US15123623

    申请日：2015-03-04

    申请人： Hirofumi YAMAMOTO ,  Masaki MORI

    发明人： Hirofumi YAMAMOTO ,  Masaki MORI ,  Yuichiro DOKI

    IPC分类号： C12N15/113

    CPC分类号： C12N15/113 ,  A61K9/0019 ,  A61K9/5115 ,  A61K47/02 ,  C12N2310/141 ,  C12N2310/351

    摘要： Provided is a novel useful microRNA having improved anti-tumour activity, obtained by introducing a variation in a microRNA which is present in-vivo and which exhibits an anti-tumour effect. This microRNA containing a base sequence (SEQ ID NO: 1) obtained by varying a predetermined region of the base sequence of miR-29b is able to exhibit a particularly outstanding anti-tumour effect.

    摘要翻译： 提供了通过引入存在于体内并且具有抗肿瘤作用的微小RNA的变异获得的具有改善的抗肿瘤活性的新型有用的微小RNA。 含有通过改变miR-29b的碱基序列的预定区域获得的碱基序列（SEQ ID NO：1）的该微小RNA能够表现出特别优异的抗肿瘤效果。

    MICROCOMPUTER
    5.
    发明申请
    MICROCOMPUTER 有权

    公开(公告)号：US20120221679A1

    公开(公告)日：2012-08-30

    申请号：US13403076

    申请日：2012-02-23

    申请人： Hirofumi YAMAMOTO ,  Yuki Horii ,  Takashi Abe ,  Shinichirou Taguchi

    发明人： Hirofumi YAMAMOTO ,  Yuki Horii ,  Takashi Abe ,  Shinichirou Taguchi

    IPC分类号： G06F15/16

    CPC分类号： G06F13/20 ,  G06F5/065 ,  G06F13/26 ,  G06F13/32 ,  G06F13/385 ,  G06F2205/065

    摘要： Between a CPU and a communication module, a write buffer, a write control section, a read buffer and a read control section are provided. The CPU directly accesses and the write buffer and the read buffer. By periodically outputting a communication request, the read control section reads data, which the communication module received from other nodes, and transfers the data to the read buffer. The write control section transfers to the communication module the data written in the write buffer as transmission data. In addition, a bypass access control section and an access sequence control section are provided. The bypass access control section controls direct data read and data write between the CPU and the communication module. The access sequence control section controls sequence of accesses of the control sections to the communication module.

    摘要翻译： 在CPU和通信模块之间，提供写入缓冲器，写入控制部分，读取缓冲器和读取控制部分。 CPU直接访问写缓冲区和读缓冲区。 通过周期性地输出通信请求，读取控制部分读取通信模块从其他节点接收的数据，并将数据传送到读取缓冲器。 写入控制部分将写入缓冲器中的数据作为传输数据传送给通信模块。 另外，提供了旁路接入控制部和接入序列控制部。 旁路访问控制部分控制CPU和通信模块之间的直接数据读取和数据写入。 访问序列控制部分控制对通信模块的控制部分的访问顺序。

    ENDOSCOPE AND HYDROPHILIC CAP
    6.
    发明申请
    ENDOSCOPE AND HYDROPHILIC CAP 有权
    内窥镜和水囊

    公开(公告)号：US20080228035A1

    公开(公告)日：2008-09-18

    申请号：US12129326

    申请日：2008-05-29

    申请人： Masahiro HAGIHARA ,  Takao YAMAGUCHI ,  Kiyoshi TSUJI ,  Atsushi GOTO ,  Hiroaki KINOSHITA ,  Hirofumi YAMAMOTO

    发明人： Masahiro HAGIHARA ,  Takao YAMAGUCHI ,  Kiyoshi TSUJI ,  Atsushi GOTO ,  Hiroaki KINOSHITA ,  Hirofumi YAMAMOTO

    IPC分类号： A61B1/00 ,  A61B1/06

    CPC分类号： G02B1/10 ,  A61B1/00071 ,  A61B1/00096 ,  A61B1/00101 ,  A61B1/0011 ,  A61B1/127 ,  G02B1/11 ,  G02B23/2423 ,  G02B23/2476

    摘要： An endoscope includes: an insertion portion including a distal end portion, to be inserted into a subject; an observation optical system disposed in the insertion portion; an optical member configuring a part of an outer surface of the distal end portion, through which a photographing light to be incident into the observation optical system transmits; a first hydrophilic portion that is film-formed at least on a surface of the optical member; a second hydrophilic portion that is film-formed on a first surface of the distal end portion in which the optical member is disposed; and a third hydrophilic portion that is film-formed on a second surface separate from the first surface of the distal end portion.

    摘要翻译： 内窥镜包括：插入部，其包括被插入到被检体内的前端部; 设置在所述插入部中的观察光学系统; 构成所述前端部的外表面的一部分的光学构件，通过所述光学构件入射到所述观察光学系统的拍摄光透过; 至少在所述光学构件的表面上成膜的第一亲水部分; 第二亲水部分，其在设置有所述光学部件的所述远端部分的第一表面上成膜; 以及第三亲水部分，其在与所述远端部分的第一表面分离的第二表面上成膜。

    ZOOM IMAGE-FORMING OPTICAL SYSTEM AND MICROSCOPE EQUIPPED THEREWITH
    7.
    发明申请
    ZOOM IMAGE-FORMING OPTICAL SYSTEM AND MICROSCOPE EQUIPPED THEREWITH 有权
    缩放成像光学系统和微型显微镜

    公开(公告)号：US20120307036A1

    公开(公告)日：2012-12-06

    申请号：US13480784

    申请日：2012-05-25

    申请人： Hirofumi YAMAMOTO

    发明人： Hirofumi YAMAMOTO

    IPC分类号： H04N7/18

    CPC分类号： G02B21/025 ,  G02B21/082

    摘要： A zoom image-forming optical system used in combination with an infinity-correction objective lens, the zoom image-forming optical system including: a tube lens for condensing a luminous flux from the objective lens to form an intermediate image; and a relay lens with a zoom function for projecting the intermediate image onto an image plane. The relay lens includes a first lens group with positive power, a second lens group that belongs to a movable group with positive power, a third lens group that belongs to a movable group with positive or negative power, and a fourth lens group with negative power, in this order from the intermediate image side. The zoom image-forming optical system changes its magnifying power by moving the second lens group and the third lens group in an optical axis direction.

    摘要翻译： 一种与无限远校正物镜组合使用的变焦图像形成光学系统，所述变焦图像形成光学系统包括：用于会聚来自所述物镜的光通量以形成中间图像的管透镜; 以及具有用于将中间图像投影到图像平面上的变焦功能的中继透镜。 中继透镜包括具有正功率的第一透镜组，属于具有正光焦度的可移动组的第二透镜组，属于具有正或负电源的可移动组的第三透镜组，以及负功率的第四透镜组 ，从中间图像侧按此顺序。 缩放图像形成光学系统通过沿着光轴方向移动第二透镜组和第三透镜组来改变其放大倍率。

    MICROSCOPE
    8.
    发明申请
    MICROSCOPE 有权
    显微镜

    公开(公告)号：US20100277581A1

    公开(公告)日：2010-11-04

    申请号：US12771021

    申请日：2010-04-30

    申请人： Yusuke MATSUMOTO ,  Hirofumi YAMAMOTO

    发明人： Yusuke MATSUMOTO ,  Hirofumi YAMAMOTO

    IPC分类号： G02B21/02 ,  H04N7/18 ,  G02B21/06

    CPC分类号： G02B21/241 ,  G02B21/36

    摘要： A microscope, which moves an objective lens along an observation optical axis with respect to a specimen, includes an imaging unit and a supporting unit. The imaging unit has an imaging lens, which is arranged on the observation optical axis and forms an observation image of the specimen, and an imaging element, which is arranged on the observation optical axis and takes the observation image, and is optically connected to the objective lens by a parallel light flux. The supporting unit fixedly supports the imaging unit, and movably supports the objective lens.

    摘要翻译： 将物镜相对于检体沿着观察光轴移动的显微镜包括成像单元和支撑单元。 成像单元具有配置在观察光轴上并形成检体的观察图像的摄像透镜和配置在观察光轴上并拍摄观察图像的摄像元件，并与光学连接 物镜采用平行光通量。 支撑单元固定地支撑成像单元，并且可移动地支撑物镜。