公开(公告)号：US08247471B2

公开(公告)日：2012-08-21

申请号：US12725657

申请日：2010-03-17

申请人： Hideki Yarimizu ,  Hideki Tokui ,  Hiroto Minamisawa

发明人： Hideki Yarimizu ,  Hideki Tokui ,  Hiroto Minamisawa

IPC分类号： C08F20/10 ,  C08F4/76

CPC分类号： C09D4/00 ,  A61K6/083 ,  A61K6/0835 ,  C09J4/00 ,  C08F220/00 ,  C08L33/04

摘要： To provide a dental adhesive composition which does not decrease preservation stability when reacting with acidity for acquiring dental adhesive property, even though using a filler having X-ray imaging property, and does not need the conventional mixing and kneading of two or more components, the dental adhesive composition includes (a) a (meth)acrylate compound having an acid group, and (b) aluminosilicate glass powder containing Sr and/or Ba and/or Ca, and the dental adhesive composition further includes a filler and (c) a photopolymerization catalyst, where the filler does not substantially make a neutralization reaction with the (meth)acrylate compound having an acid group as the (a) component because a filler content is 15% by weight or less in terms of oxide of Al2O3, and those coexist is one.

摘要翻译： 为了提供一种牙科粘合剂组合物，即使使用具有X射线成像特性的填料，也不需要常规的两种或多种组分的混合和捏合，即使与用于获得牙科粘合性的酸度反应而不会降低保存稳定性， 牙科粘合剂组合物包含（a）具有酸基的（甲基）丙烯酸酯化合物，和（b）含有Sr和/或Ba和/或Ca的铝硅酸盐玻璃粉末，并且所述牙科粘合剂组合物还包含填料和（c） 光聚合催化剂，其中填料与具有酸基的（甲基）丙烯酸酯化合物作为（a）成分基本上不进行中和反应，因为填料含量以Al 2 O 3的氧化物计为15重量％以下， 共存是一个。

公开(公告)号：US08247470B2

公开(公告)日：2012-08-21

申请号：US12728711

申请日：2010-03-22

申请人： Hideki Yarimizu ,  Hideki Tokui ,  Hiroto Minamisawa

发明人： Hideki Yarimizu ,  Hideki Tokui ,  Hiroto Minamisawa

IPC分类号： A61K6/083 ,  C08K3/40

CPC分类号： C09J4/06 ,  A61K6/083 ,  A61K6/0835 ,  A61K6/09 ,  C08F4/40 ,  C08L33/00 ,  C08L75/16

摘要： To provide a polymerizable composition having more excellent preservation stability of pastes than a conventional composition using a combination of a copper compound, cumene hydroperoxide, and N-acetylthiourea, and having a polymerization curing time which does not change with time, that is, does not delay or quicken from a time set for a product even though the composition is stored, the polymerizable composition includes a first paste and a second paste, wherein the first paste includes a polymer of α-β unsaturated monocarboxylic acid or α-β unsaturated dicarboxylic acid, water, and a hydroperoxide as a peroxide, and the second paste includes a (meth)acrylate compound not having an acid group, fluoroaluminosilicate glass powder, a thiourea derivative as a reducing material, and a vanadium compound as a polumerization accelerator.

摘要翻译： 为了提供具有比铜化合物，氢过氧化枯烯和N-乙酰基硫脲组合的常规组合物更优异的糊剂保存稳定性的聚合性组合物，并且具有不随时间变化的聚合固化时间，即不 延迟或加速，即使存在组合物，可聚合组合物包括第一糊剂和第二糊剂，其中第一糊剂包括α-淀粉的聚合物; 不饱和一元羧酸或α- 不饱和二羧酸，水和作为过氧化物的氢过氧化物，第二糊剂包括不具有酸基的（甲基）丙烯酸酯化合物，氟铝硅酸盐玻璃粉末，作为还原剂的硫脲衍生物和作为聚合促进剂的钒化合物 。

公开(公告)号：US20100249266A1

公开(公告)日：2010-09-30

申请号：US12728711

申请日：2010-03-22

申请人： Hideki Yarimizu ,  Hideki Tokui ,  Hiroto Minamisawa

发明人： Hideki Yarimizu ,  Hideki Tokui ,  Hiroto Minamisawa

IPC分类号： A61L24/06

CPC分类号： C09J4/06 ,  A61K6/083 ,  A61K6/0835 ,  A61K6/09 ,  C08F4/40 ,  C08L33/00 ,  C08L75/16

摘要： To provide a polymerizable composition having more excellent preservation stability of pastes than a conventional composition using a combination of a copper compound, cumene hydroperoxide, and N-acetylthiourea, and having a polymerization curing time which does not change with time, that is, does not delay or quicken from a time set for a product even though the composition is stored, the polymerizable composition includes a first paste and a second paste, wherein the first paste includes a polymer of α-β unsaturated monocarboxylic acid or α-β unsaturated dicarboxylic acid, water, and a hydroperoxide as a peroxide, and the second paste includes a (meth)acrylate compound not having an acid group, fluoroaluminosilicate glass powder, a thiourea derivative as a reducing material, and a vanadium compound as a polumerization accelerator.

摘要翻译： 为了提供具有比铜化合物，氢过氧化枯烯和N-乙酰基硫脲组合的常规组合物更优异的糊剂保存稳定性的聚合性组合物，并且具有不随时间变化的聚合固化时间，即不 延迟或加速，即使存在组合物，可聚合组合物包括第一糊剂和第二糊剂，其中第一糊剂包括α-淀粉的聚合物; 不饱和一元羧酸或α- 不饱和二羧酸，水和作为过氧化物的氢过氧化物，第二糊剂包括不具有酸基的（甲基）丙烯酸酯化合物，氟铝硅酸盐玻璃粉末，作为还原剂的硫脲衍生物和作为聚合促进剂的钒化合物 。

公开(公告)号：US20100204421A1

公开(公告)日：2010-08-12

申请号：US12704883

申请日：2010-02-12

申请人： Hideki Yarimizu ,  Hideki Tokui ,  Hisashi Nakaseko

发明人： Hideki Yarimizu ,  Hideki Tokui ,  Hisashi Nakaseko

IPC分类号： C08F20/10 ,  C09K3/00

CPC分类号： C08F4/28 ,  A61K6/083 ,  C08F4/40 ,  C08L33/04

摘要： To provide initiators in two components having no discoloring after polymerization and excellent polymerization-curability under the existence of water, and provide a polymerizable composition using the initiators in two components. The initiators in two components is for polymerizing and curing a (meth)acrylate compound, and the initiator includes (a) a peroxide being compatible or soluble with water, (b) an aromatic sulfinic acid compound, (c) a tert-amine compound, and (d) water. The polymerizable composition uses the initiators in two components. Particularly, preferably, the polymerizable composition includes a first component and a second component. The first component comprising (a) a peroxide being compatible or soluble with water, and a (meth)acrylate compound, and the second component includes (b) an aromatic sulfinic acid compound, (c) a tert-amine compound, and (d) water.

摘要翻译： 为了在聚合后没有变色的两个组分提供引发剂，并且在水存在下具有优异的聚合固化性，并且使用两种组分中的引发剂提供可聚合组合物。 两种组分中的引发剂用于聚合和固化（甲基）丙烯酸酯化合物，并且引发剂包括（a）与水相容或可溶的过氧化物，（b）芳香族亚磺酸化合物，（c）叔胺化合物 ，（d）水。 可聚合组合物使用两种组分的引发剂。 特别地，优选地，可聚合组合物包括第一组分和第二组分。 第一组分包含（a）与水相容或可溶的过氧化物和（甲基）丙烯酸酯化合物，和第二组分包括（b）芳香族亚磺酸化合物，（c）叔胺化合物和（d ） 水。

公开(公告)号：US20110046256A1

公开(公告)日：2011-02-24

申请号：US12835216

申请日：2010-07-13

申请人： Hideki Yarimizu ,  Hideki Tokui ,  Sayaka Nagao

发明人： Hideki Yarimizu ,  Hideki Tokui ,  Sayaka Nagao

IPC分类号： A61K6/00

CPC分类号： A61K6/0023 ,  C08L33/10

摘要： To provide a tooth-adhesive composition not causing lowering of preservation stability due to a reaction between a filler having a X-ray imaging property and an acid component in the composition, and not having necessity for mixing and kneading of components separated in two or more packages unlike a conventional case, the tooth-adhesive composition includes (a) a (meth)acrylate compound having an acid group, (b) a filler which is an alumino-silicate glass powder including Sr and/or Ba and/or Ca, and (c) a photopolymerization catalyst, where the filler does not substantially react with the (meth)acrylate compound having an acid group, which is the a) component, by making Al2O3 content to be 15% or less by weight in terms of oxides, and these (a), (b), and (c) components co-exist in one pack.

摘要翻译： 为了提供一种牙膏组合物，不会由于在组合物中具有X射线成像特性的填料和酸成分之间的反应而导致保存稳定性降低，并且不需要混合和捏合在两个或更多个中分离的组分 所述牙胶组合物包含（a）具有酸基的（甲基）丙烯酸酯化合物，（b）作为包含Sr和/或Ba和/或Ca的铝硅酸盐玻璃粉末的填料， 和（c）光聚合催化剂，其中通过使氧化铝的Al 2 O 3含量为15重量％以下，填充剂基本上不与具有酸基团的（甲基）丙烯酸酯化合物即a）成分反应 ，这些（a），（b）和（c）成分共存在一个包装中。

公开(公告)号：US20080015279A1

公开(公告)日：2008-01-17

申请号：US11774759

申请日：2007-07-09

申请人： Hideki TOKUI ,  Hideki Yarimizu ,  Daisuke Ota ,  Takuya Mori ,  Hisashi Nakaseko

发明人： Hideki TOKUI ,  Hideki Yarimizu ,  Daisuke Ota ,  Takuya Mori ,  Hisashi Nakaseko

IPC分类号： A61K6/083

CPC分类号： A61K6/083 ,  C08L33/00 ,  C08L43/02

摘要： A dental cement comprises a first paste including a (meth)acrylate monomer having an acid group, the (meth)acrylate monomer not having an acid group, having two or less of hydroxyl groups and/or amino groups and having a molecular weight of 160 or more, the filler having a specific average particle size and being inactive to the (meth)acrylate monomer having an acid group, and the amine compound as a accelerator for the undermentioned polymerizing catalyst; and the second paste including a (meth)acrylate monomer not having an acid group, having two or less of hydroxyl groups and/or amino groups and having a molecular weight of 160 or more, a filler having a specific particle size, and an organic aromatic compound having at least one —SO2— group and the peroxide as a polymerizing catalyst, thereby providing a dental cement large flexural strength, adhesiveness to dentin, small hygroscopic expansion, and low solubility.

摘要翻译： 牙科水泥包括含有具有酸基的（甲基）丙烯酸酯单体的第一糊剂，不具有酸基的（甲基）丙烯酸酯单体，具有两个或多个羟基和/或氨基并且分子量为160 或更多，具有特定平均粒径并且对具有酸基的（甲基）丙烯酸酯单体无活性的填料和作为下述聚合催化剂的促进剂的胺化合物; 所述第二糊剂包含不具有酸基的（甲基）丙烯酸酯单体，具有2个以下羟基和/或氨基，分子量为160以上，具有特定粒径的填料和有机物 具有至少一个-SO 2 - 基的芳族化合物和作为聚合催化剂的过氧化物，从而提供牙科粘合剂大的弯曲强度，对牙本质的粘附性，小吸湿膨胀和低溶解度。

公开(公告)号：US20090018234A1

公开(公告)日：2009-01-15

申请号：US11774861

申请日：2007-07-09

申请人： Hideki TOKUI ,  Hideki Yarimizu ,  Takuya Mori ,  Daisuke Ota ,  Hisashi Nakaseko

发明人： Hideki TOKUI ,  Hideki Yarimizu ,  Takuya Mori ,  Daisuke Ota ,  Hisashi Nakaseko

IPC分类号： A61K6/083

CPC分类号： A61L27/10 ,  A61K6/0835 ,  A61L24/12 ,  C08L33/00 ,  C08L43/02

摘要： In order to decrease hydroscopic expansion of a resin-modified dental glass ionomer cement without losing high mechanical strength and adhesiveness to tooth structure and to lower a solubility, a dental cement consists of a liquid agent which includes a (meth)acrylate monomer having an acid group; a (meth)acrylate monomer having two or less hydroxyl groups and/or amino groups, not having an acid group, and having 160 or more molecular weight; water if necessary; and an amine compound as a polymerization initiator for a polymerization catalyst in a powder agent, and a powder agent which includes metal oxide powder used for fluoroaluminosilicate glass powder, dental zinc phosphate cement powder or dental carboxylate cement powder; and an organic aromatic compound and a peroxide, where the organic aromatic compound contains at least one —SO2— group as a polymerization catalyst.

摘要翻译： 为了降低树脂改性牙科玻璃离聚物粘固剂的吸湿膨胀而不损失机械强度和与牙齿结构的粘合性并降低溶解度，牙科粘固剂由包含具有酸的（甲基）丙烯酸酯单体的液体试剂组成 组; 具有两个或更少羟基和/或氨基的不具有酸基并且具有160以上分子量的（甲基）丙烯酸酯单体; 水必要时; 以及作为粉末剂中的聚合催化剂的聚合引发剂的胺化合物和包含用于氟铝硅酸盐玻璃粉末，磷酸锌水泥粉末或牙本质羧酸盐水泥粉末的金属氧化物粉末的粉末剂; 和有机芳族化合物和过氧化物，其中有机芳族化合物含有至少一个-SO 2 - 基团作为聚合催化剂。

公开(公告)号：US20070031779A1

公开(公告)日：2007-02-08

申请号：US11493524

申请日：2006-07-27

申请人： Hideki Tokui ,  Hideki Yarimizu ,  Daisuke Ota ,  Takuya Mori ,  Hisashi Nakaseko

发明人： Hideki Tokui ,  Hideki Yarimizu ,  Daisuke Ota ,  Takuya Mori ,  Hisashi Nakaseko

IPC分类号： A61C5/04

CPC分类号： B05C17/00516 ,  A61C5/62

摘要： To separate a catalyst for polymerizing a monomer contained in a liquid or paste dental composition containing at least a monomer, such as a dental resin cement, an autopolymerizing dental resin or a resin-reinforced dental glass ionomer cement, from the liquid or paste dental composition to thereby improve storage stability of the dental composition and reduce number of division of the dental composition, an extrusion nozzle for a dental composition mounted on one end of an extruder for extruding a liquid or paste dental composition containing at least a monomer, the extrusion nozzle contains a catalyst for polymerizing the monomer contained in the dental composition during extrusion, and the catalyst is attached to an inner wall of an extruding channel of the extrusion nozzle.

摘要翻译： 为了分离用于使含有至少含有单体（例如牙科树脂水泥，自聚合牙科树脂或树脂增强牙科玻璃离聚物粘固剂）的液体或糊状牙科组合物中包含的单体从用于聚合液体或糊状牙科组合物 从而提高牙科用组合物的保存稳定性，减少牙科用组合物的分割，将用于挤出含有至少一种单体的液体或糊剂牙科用组合物的牙科用组合物的挤出喷嘴安装在挤出机的一端，挤出喷嘴 含有用于在挤出期间使包含在牙科用组合物中的单体聚合的催化剂，并且催化剂附着到挤出喷嘴的挤压通道的内壁。

公开(公告)号：US20120077901A1

公开(公告)日：2012-03-29

申请号：US13242917

申请日：2011-09-23

申请人： Koji Tanaka ,  Daisuke Ota ,  Hideki Yarimizu

发明人： Koji Tanaka ,  Daisuke Ota ,  Hideki Yarimizu

IPC分类号： A61K6/08

CPC分类号： A61K6/0835 ,  A61K6/0047 ,  A61K6/0091 ,  C08L33/00 ,  C08L31/04 ,  C08L27/06

摘要： To provide a dental glass ionomer cement composition having excellent adhesion strength to a metallic prosthesis. A dental glass ionomer cement composition includes a copolymer (A), a fluoroaluminosilicate glass powder (B) and water (C). The copolymer (A) includes a polymer or copolymer of α-β unsaturated carboxylic acid, or includes a copolymer of α-β unsaturated carboxylic acid and one or more kinds selected from a group of acrylamide, acrylonitrile, methacrylic acid ester, acrylates, vinyl chloride, allyl chloride and vinyl acetate. In the copolymer (A), the number of molecules of α-β unsaturated carboxylic acid occupies 50% or more of the total number of molecules. The dental glass ionomer cement composition further includes a compound (D) which contains a sulfur atom in one molecule, includes a carboxylic group and an amino group and does not include a polymerizable group.

摘要翻译： 提供对金属假体具有优异粘合强度的牙科玻璃离聚物粘合剂组合物。 牙科玻璃离聚物粘合剂组合物包括共聚物（A），氟铝硅酸盐玻璃粉末（B）和水（C）。 共聚物（A）包括α-和bgr的聚合物或共聚物; 不饱和羧酸，或包括α-和bgr的共聚物; 不饱和羧酸和选自丙烯酰胺，丙烯腈，甲基丙烯酸酯，丙烯酸酯，氯乙烯，烯丙基氯和乙酸乙烯酯中的一种或多种。 在共聚物（A）中，α-＆bgr的分子数; 不饱和羧酸占分子总数的50％以上。 牙科玻璃离聚物粘固剂组合物还包括在一个分子中含有硫原子的化合物（D），包括羧基和氨基，并且不包括可聚合基团。

公开(公告)号：US20100063176A1

公开(公告)日：2010-03-11

申请号：US12553344

申请日：2009-09-03

申请人： Katsuhito KATO ,  Hideki Yarimizu

发明人： Katsuhito KATO ,  Hideki Yarimizu

IPC分类号： A61K6/083

CPC分类号： A61L24/12 ,  A61K6/0276 ,  A61K6/083 ,  A61K6/0835 ,  C08L33/00

摘要： To provide a paste-type dental cement capable of being used properly for temporary adhering or temporary filling, a paste-type dental cement, which comprises a phosphoric acid and/or a polymer of α-β unsaturated carboxylic acid, an oxide powder capable of reacting with the phosphoric acid and/or the polymer of α-β unsaturated carboxylic acid, and a water, further includes a liquid not reacting with the oxide powder.

摘要翻译： 为了提供能够适当地用于临时粘合或临时填充的糊状牙科粘固剂，其包含磷酸和/或α-淀粉的聚合物的糊状牙科粘固剂; 不饱和羧酸，能与磷酸和/或α-和bgr的聚合物反应的氧化物粉末; 不饱和羧酸和水，还包括不与氧化物粉末反应的液体。