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公开(公告)号:US12125261B2
公开(公告)日:2024-10-22
申请号:US17817737
申请日:2022-08-05
申请人: HeartFlow, Inc.
IPC分类号: G06T7/00 , G06F18/2415 , G06T7/11 , G06T7/13 , G06T7/143 , G06T7/60 , G06V10/764 , A61B6/50
CPC分类号: G06V10/764 , G06F18/2415 , G06T7/0014 , G06T7/11 , G06T7/13 , G06T7/143 , G06T7/60 , A61B6/504 , G06T2200/04 , G06T2207/20076 , G06T2207/20081 , G06T2207/20084 , G06T2207/30101 , G06T2207/30104 , G06T2207/30172
摘要: Systems and methods are disclosed for performing probabilistic segmentation in anatomical image analysis, using a computer system. One method includes receiving a plurality of images of an anatomical structure; receiving one or more geometric labels of the anatomical structure; generating a parametrized representation of the anatomical structure based on the one or more geometric labels and the received plurality of images; mapping a region of the parameterized representation to a geometric parameter of the anatomical structure; receiving an image of a patient's anatomy; and generating a probability distribution for a patient-specific segmentation boundary of the patient's anatomy, based on the mapping of the region of the parameterized representation of the anatomical structure to the geometric parameter of the anatomical structure.
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公开(公告)号:US12112483B2
公开(公告)日:2024-10-08
申请号:US18171915
申请日:2023-02-21
申请人: HeartFlow, Inc.
CPC分类号: G06T7/174 , G06T7/0012 , G06T7/12 , G06T7/149 , G06T2200/04 , G06T2207/10072 , G06T2207/10081 , G06T2207/10088 , G06T2207/10104 , G06T2207/10108 , G06T2207/10132 , G06T2207/20081 , G06T2207/20112 , G06T2207/30004 , G06T2207/30101 , G06V2201/03
摘要: Systems and methods are disclosed for anatomic structure segmentation in image analysis, using a computer system. One method includes: receiving an annotation and a plurality of keypoints for an anatomic structure in one or more images; computing distances from the plurality of keypoints to a boundary of the anatomic structure; training a model, using data in the one or more images and the computed distances, for predicting a boundary in the anatomic structure in an image of a patient's anatomy; receiving the image of the patient's anatomy including the anatomic structure; estimating a segmentation boundary in the anatomic structure in the image of the patient's anatomy; and predicting, using the trained model, a boundary location in the anatomic structure in the image of the patient's anatomy by generating a regression of distances from keypoints in the anatomic structure in the image of the patient's anatomy to the estimated boundary.
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公开(公告)号:US11501485B2
公开(公告)日:2022-11-15
申请号:US16993322
申请日:2020-08-14
申请人: HeartFlow, Inc.
发明人: Leo Grady , Michiel Schaap
摘要: Systems and methods are disclosed for integrating imaging data from multiple sources to create a single, accurate model of a patient's anatomy. One method includes receiving a representation of a target object for modeling; determining one or more first anatomical parameters of the target anatomical object from at least one of one or more first images of the target anatomical object; determining one or more second anatomical parameters of the target anatomical object from at least one of one or more second images of the target anatomical object; updating the one or more first anatomical parameters based at least on the one or more second anatomical parameters; and generating a model of the target anatomical object based on the updated first anatomical parameters.
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公开(公告)号:US11494904B2
公开(公告)日:2022-11-08
申请号:US16902721
申请日:2020-06-16
申请人: HeartFlow, Inc.
发明人: Timothy A. Fonte , Leo Grady , Zhongle Wu , Michiel Schaap , Stanley C. Hunley , Souma Sengupta , Sophie Khem
摘要: Systems and methods are disclosed for assessing the quality of medical images of at least a portion of a patient's anatomy, using a computer system. One method includes receiving one or more images of at least a portion of the patient's anatomy; determining, using a processor of the computer system, one or more image properties of the received images; performing, using a processor of the computer system, anatomic localization or modeling of at least a portion of the patient's anatomy based on the received images; obtaining an identification of one or more image characteristics associated with an anatomic feature of the patient's anatomy based on the anatomic localization or modeling; and calculating, using a processor of the computer system, an image quality score based on the one or more image properties and the one or more image characteristics.
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公开(公告)号:US11213354B2
公开(公告)日:2022-01-04
申请号:US16871216
申请日:2020-05-11
申请人: HeartFlow, Inc.
发明人: Leo Grady , Michiel Schaap , Sophie Khem , Sarah Wilkes , Ying Bai
IPC分类号: A61B34/10 , G16H50/50 , G16B5/00 , G06F30/20 , G06T7/00 , G06T7/70 , G06K9/62 , G06T7/60 , G09B9/00 , G09B23/30 , A61B6/00 , G06T13/20
摘要: Systems and methods are disclosed for correcting for artificial deformations in anatomical modeling. One method includes obtaining an anatomic model; obtaining information indicating a presence of an artificial deformation of the anatomic model; identifying a portion of the anatomic model associated with the artificial deformation; estimating a non-deformed local area corresponding to the portion of the anatomic model; and modifying the portion of the anatomic model associated with the artificial deformation, based on the estimated non-deformed local area.
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公开(公告)号:US10984535B2
公开(公告)日:2021-04-20
申请号:US17013922
申请日:2020-09-08
申请人: Heartflow, Inc.
摘要: Systems and methods are disclosed for anatomic structure segmentation in image analysis, using a computer system. One method includes: receiving an annotation and a plurality of keypoints for an anatomic structure in one or more images; computing distances from the plurality of keypoints to a boundary of the anatomic structure; training a model, using data in the one or more images and the computed distances, for predicting a boundary in the anatomic structure in an image of a patient's anatomy; receiving the image of the patient's anatomy including the anatomic structure; estimating a segmentation boundary in the anatomic structure in the image of the patient's anatomy; and predicting, using the trained model, a boundary location in the anatomic structure in the image of the patient's anatomy by generating a regression of distances from keypoints in the anatomic structure in the image of the patient's anatomy to the estimated boundary.
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公开(公告)号:US10682183B2
公开(公告)日:2020-06-16
申请号:US15961331
申请日:2018-04-24
申请人: HeartFlow, Inc.
发明人: Leo Grady , Michiel Schaap , Sophie Khem , Sarah Wilkes , Ying Bai
IPC分类号: A61B34/10 , G16H50/50 , G16B5/00 , G06F30/20 , G06T7/00 , G06T7/70 , G06K9/62 , G06T7/60 , G09B9/00 , G09B23/30 , A61B6/00 , G06T13/20
摘要: Systems and methods are disclosed for correcting for artificial deformations in anatomical modeling. One method includes obtaining an anatomic model; obtaining information indicating a presence of an artificial deformation of the anatomic model; identifying a portion of the anatomic model associated with the artificial deformation; estimating a non-deformed local area corresponding to the portion of the anatomic model; and modifying the portion of the anatomic model associated with the artificial deformation, based on the estimated non-deformed local area.
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公开(公告)号:US10405925B2
公开(公告)日:2019-09-10
申请号:US15088512
申请日:2016-04-01
申请人: HeartFlow, Inc.
发明人: Clara Jaquet , Michiel Schaap , Ying Bai , Leo Grady , Charles A. Taylor
摘要: Systems and methods are disclosed for creating an interactive tool for determining and displaying a functional relationship between a vascular network and an associated perfused tissue. One method includes receiving a patient-specific vascular model of a patient's anatomy, including at least one vessel of the patient; receiving a patient-specific tissue model, including a tissue region associated with the at least one vessel of the patient; receiving a selected area of the vascular model or a selected area of the tissue model; and generating a display of a region of the tissue model corresponding to the selected area of the vascular model or a display of a portion of the vascular model corresponding to the selected area of the tissue model, respectively.
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公开(公告)号:US10262101B2
公开(公告)日:2019-04-16
申请号:US15088733
申请日:2016-04-01
申请人: HeartFlow, Inc.
发明人: Leo Grady , Michiel Schaap , Charles A. Taylor , Clara Jaquet
摘要: Systems and methods are disclosed for using patient specific anatomical models and physiological parameters to estimate perfusion of a target tissue to guide diagnosis or treatment of cardiovascular disease. One method includes receiving a patient-specific vessel model and a patent-specific tissue model of a patient anatomy; extracting one or more patient-specific physiological parameters (e.g. blood flow, anatomical characteristics, image characteristics, etc.) from the vessel or tissue models for one or more physiological states of the patient; estimating a characteristic of the perfusion of the patient-specific tissue model (e.g., via a trained machine learning algorithm) using the patient-specific physiological parameters; and outputting the estimated perfusion characteristic to a display.
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公开(公告)号:US09672615B2
公开(公告)日:2017-06-06
申请号:US14554653
申请日:2014-11-26
申请人: HeartFlow, Inc.
发明人: Timothy A. Fonte , Leo J. Grady , Zhongle Wu , Michiel Schaap , Stanley C. Hunley , Souma Sengupta
CPC分类号: G06T7/0012 , A61B5/026 , A61B5/0261 , A61B5/0263 , A61B6/032 , A61B6/037 , A61B6/481 , A61B6/504 , A61B6/507 , A61B6/5217 , A61B6/5258 , A61B6/5294 , A61B8/0883 , A61B8/5223 , A61B2576/02 , G01R33/5635 , G06T2207/10081 , G06T2207/10088 , G06T2207/10104 , G06T2207/10108 , G06T2207/10132 , G06T2207/30004 , G06T2207/30104 , G06T2207/30168 , G06T2207/30172 , G06T2207/30196 , G06T2210/41 , G16H50/50
摘要: Systems and methods are disclosed for assessing the quality of medical images of at least a portion of a patient's anatomy, using a computer system. One method includes receiving one or more images of at least a portion of the patient's anatomy; determining, using a processor of the computer system, one or more image properties of the received images; performing, using a processor of the computer system, anatomic localization or modeling of at least a portion of the patient's anatomy based on the received images; obtaining an identification of one or more image characteristics associated with an anatomic feature of the patient's anatomy based on the anatomic localization or modeling; and calculating, using a processor of the computer system, an image quality score based on the one or more image properties and the one or more image characteristics.
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