公开(公告)号：US20250137993A1

公开(公告)日：2025-05-01

申请号：US18835747

申请日：2022-10-06

Applicant: Hitachi High-Tech Corporation

Inventor： Michiko FUKUYAMA ,  Chie YABUTANI

IPC: G01N33/49 ,  G01N21/25 ,  G01N21/27 ,  G01N35/00 ,  G01N35/10

Abstract: An automatic analysis device includes: a specimen dispenser mechanism; a reagent dispenser mechanism; a measuring unit; an analysis operation control unit that controls the operation of the specimen dispenser mechanism, the reagent dispenser mechanism and the measuring unit; a coagulation time arithmetic unit that calculates a coagulation time on the basis of light intensity measured at the measuring unit; a graph generating unit that generates a graph pertaining to the coagulation time of each preparation specimen calculated at the coagulation time arithmetic unit; and a display unit that displays the graph generated by the graph generating unit, wherein if a preparation specimen exists for which a coagulation time cannot be calculated, the graph generating unit generates a graph using at least either a coagulation time calculated for a preparation specimen prepared outside the automatic analysis device, or an estimated coagulation time on the basis of the light intensity measured.

公开(公告)号：US20200326353A1

公开(公告)日：2020-10-15

申请号：US16912897

申请日：2020-06-26

Applicant: Hitachi High-Tech Corporation

Inventor： Chie YABUTANI ,  Naoto SUZUKI ,  Akihisa MAKINO

IPC: G01N33/86 ,  G01N35/04 ,  G01N33/96 ,  G01N21/82 ,  G01N35/02 ,  G01N33/49 ,  G01N35/00 ,  G01N21/27 ,  G01N35/10

Abstract: The automatic analysis device 100 is provided with: a specimen dispensing mechanism 101 that dispenses subject blood plasma and/or normal blood plasma to be added to correct the coagulation time of the subject blood plasma, into a plurality of specimen containers 103; reaction containers 104 that contain the subject blood plasma and/or the normal blood plasma; a reagent dispensing mechanism 106 that dispenses a reagent into the reaction containers 104; and a detecting unit 113 which applies light from a light source 115 to the subject blood plasma and/or the normal blood plasma to which the reagent is added in the reaction containers 104, and which measures the coagulation time on the basis of the obtained scattered light and/or transmitted light.

公开(公告)号：US20250027964A1

公开(公告)日：2025-01-23

申请号：US18850600

申请日：2023-04-06

Applicant: Hitachi High-Tech Corporation

Inventor： Fuyuki MUKAI ,  Chie YABUTANI

IPC: G01N35/02 ,  G01N35/00 ,  G01N35/04 ,  G01N35/10

Abstract: Provided is an automatic analysis device having an incubation function. An example of the automatic analysis device includes: a reaction vessel storage section where a reaction vessel storage container that stores reaction vessels is installed; and a dispensing mechanism that dispenses specimens or reagents into a reaction vessel which was removed from the reaction vessel storage container. The reaction vessel storage section has a temperature-controlled area where at least a portion of the storage section is adjusted to a prescribed temperature. The reaction vessel into which a specimen or a reagent is dispensed by the dispensing mechanism is placed in a reaction vessel storage container installed in the temperature-controlled area for a prescribed period.

公开(公告)号：US20230258669A1

公开(公告)日：2023-08-17

申请号：US18014519

申请日：2021-02-19

Applicant: HITACHI HIGH-TECH CORPORATION

Inventor： Kyoko YAMAMOTO ,  Sakuichiro ADACHI ,  Chie YABUTANI

IPC: G01N35/00 ,  G01N21/77

CPC classification number: G01N35/00693 ,  G01N21/77 ,  G01N2035/00702

Abstract: An object of the present invention is to suppress time and effort into generating a calibration curve while ensuring accuracy of the calibration curve in an analysis step of generating the calibration curve by using two or more standard solutions (two or more concentrations). A calibration curve generation method according to the present invention includes acquiring time course data by irradiating a mixed reaction liquid obtained by mixing one standard solution containing a component to be measured having a concentration other than a zero concentration and a reagent reacting with the component to be measured with light and measuring a turbidity change over time of the mixed reaction liquid, extracting pieces of light amount data in a plurality of different times from a fitting line obtained by complementing discrete portions of the time course data, and generating the calibration curve indicating a relationship between the plurality of pieces of light amount data and a plurality of concentrations by converting the plurality of different times into the plurality of concentrations of the component to be measured (FIG. 1).

公开(公告)号：US20240353436A1

公开(公告)日：2024-10-24

申请号：US18291975

申请日：2022-05-24

Applicant: Hitachi High-Tech Corporation

Inventor： Mayuko GOTO ,  Akihiro IGUCHI ,  Chie YABUTANI

IPC: G01N35/00

CPC classification number: G01N35/00722 ,  G01N2035/0091

Abstract: The present invention provides an autonomous analysis device with which an operator can easily associate and confirm a reaction course and an illness. The device comprises an analysis unit for analyzing a sample, an operation unit for receiving an operation from an operator, a control unit for controlling the analysis unit on the basis of an input from the operation unit and computing measurement data using a measurement value acquired from the analysis unit, and a display unit for displaying the measurement data computed by the control unit, wherein the control unit causes the display unit to display not only measurement reaction course information that is based on the measurement data of the sample being analyzed, but also reference reaction course information that is designated by the operation unit from among items of reference reaction course information classified in advance for each illness.

公开(公告)号：US20210293841A1

公开(公告)日：2021-09-23

申请号：US17265726

申请日：2019-06-27

Applicant: Hitachi High-Tech Corporation

Inventor： Nobuhiko SASAKI ,  Takanori SAWADA ,  Toshiyuki SHIMAMORI ,  Chie YABUTANI

IPC: G01N35/10

Abstract: A chemical dispensing mechanism detects the liquid surface of a chemical including a chemical container mounted on a chemical disk. A calculation control unit controls the operation of the chemical dispensing mechanism. The calculation control unit performs a first raising operation, in which a chemical stored in the chemical container is suctioned by the chemical dispensing mechanism, which is then raised up to a first bubble detection position, determines whether a liquid surface is present, and outputs an alert indicating the presence of a bubble on the liquid surface when the liquid surface has been determined to be absent. The first bubble detection position is when the tip of a dispensing nozzle of the chemical dispensing mechanism remains inside the liquid when there are no bubbles present on the liquid surface, and is exposed from the inside of the liquid when there are bubbles present on the liquid surface.

公开(公告)号：US20210025911A1

公开(公告)日：2021-01-28

申请号：US16982146

申请日：2019-03-11

Applicant: HITACHI HIGH-TECH CORPORATION

Inventor： Sakuichiro ADACHI ,  Kyoko YAMAMOTO ,  Chie YABUTANI ,  Rei KONISHI ,  Akihisa MAKINO

IPC: G01N35/10

Abstract: It is necessary to efficiently agitate a small amount of sample (such as blood) and reagent (such as diluted solution) in a short time with a dispensing probe having a constant tube inner diameter. An automatic analysis device, by a dispensing probe, executes an aspiration step of aspirating a reagent from a reagent vessel; a first dispensing and aspiration step of dispensing a first liquid amount of the aspirated reagent to a reaction vessel and aspirating, from the reaction vessel, a second liquid amount of a mixed liquid obtained by mixing the reagent and the sample in the reaction vessel; and a final dispensing step of dispensing the aspirated mixed liquid and the reagent in a predetermined dispensing amount. A first liquid amount Va is less than a predetermined dispensing amount Vdil.

公开(公告)号：US20250138042A1

公开(公告)日：2025-05-01

申请号：US18835490

申请日：2022-12-21

Applicant: Hitachi High-Tech Corporation

Inventor： Kyohei MATSUDA ,  Masaaki HIRANO ,  Eiichiro TAKADA ,  Yuto FUKUYAMA ,  Chie YABUTANI ,  Masafumi SHIMADA

IPC: G01N35/10

Abstract: Provided is an automatic analyzer and a control method thereof that are capable of preventing liquid leakage when a dispensing probe that aspirated air and a liquid in order rises. The automatic analyzer for analyzing a sample includes: a dispensing unit configured to dispense the sample and/or a reagent; and a control unit configured to control the dispensing unit. When a dispensing probe provided in the dispensing unit rises after aspirating air and a liquid in order, the control unit aspirates an amount of outside air corresponding to a length of expansion of the air through a tip of the dispensing probe.

公开(公告)号：US20240192234A1

公开(公告)日：2024-06-13

申请号：US18586662

申请日：2024-02-26

Applicant: Hitachi High-Tech Corporation

Inventor： Chie YABUTANI ,  Naoto SUZUKI ,  Akihisa MAKINO

IPC: G01N33/86 ,  G01N1/38 ,  G01N21/27 ,  G01N21/82 ,  G01N33/49 ,  G01N33/96 ,  G01N35/00 ,  G01N35/02 ,  G01N35/04 ,  G01N35/10

CPC classification number: G01N33/86 ,  G01N21/272 ,  G01N21/82 ,  G01N33/4905 ,  G01N33/96 ,  G01N35/00 ,  G01N35/00722 ,  G01N35/00732 ,  G01N35/0092 ,  G01N35/0095 ,  G01N35/02 ,  G01N35/025 ,  G01N35/04 ,  G01N35/1002 ,  G01N1/38 ,  G01N2035/00356 ,  G01N2035/00534 ,  G01N2035/00544 ,  G01N2035/00554 ,  G01N2035/00831 ,  G01N2035/00891 ,  G01N2035/0094 ,  G01N2035/0441 ,  G01N2035/0444

Abstract: The automatic analysis device 100 is provided with: a specimen dispensing mechanism 101 that dispenses subject blood plasma and/or normal blood plasma to be added to correct the coagulation time of the subject blood plasma, into a plurality of specimen containers 103; reaction containers 104 that contain the subject blood plasma and/or the normal blood plasma; a reagent dispensing mechanism 106 that dispenses a reagent into the reaction containers 104; and a detecting unit 113 which applies light from a light source 115 to the subject blood plasma and/or the normal blood plasma to which the reagent is added in the reaction containers 104, and which measures the coagulation time on the basis of the obtained scattered light and/or transmitted light.

公开(公告)号：US20230408537A1

公开(公告)日：2023-12-21

申请号：US18221980

申请日：2023-07-14

Applicant: HITACHI HIGH-TECH CORPORATION

Inventor： Chie YABUTANI ,  Takumi YAMADA ,  Masahiko IIJIMA

IPC: G01N35/02 ,  G01N35/00 ,  G01N35/10

CPC classification number: G01N35/025 ,  G01N35/00663 ,  G01N35/00693 ,  G01N35/1002 ,  G01N2035/00673

Abstract: An automatic analysis device is provided with: a sample disk for holding a sample container that accommodates a sample; a reagent disk for holding a reagent container that accommodates a reagent; at least two different measuring units that respectively perform different types of analyses; a control part that controls the measuring units; and a display part that displays: a work flow area in which the flow of operation of the two or more measuring units is displayed; and an overview area in which the usable or unusable states of the respective measuring units are displayed, wherein the overview area has a unit necessity-of-use selection part that can select whether using each of the measuring units is necessary, and the control part controls the display part so as to change the display of the work flow area on the basis of the information set in the unit necessity-of-use selection part.