公开(公告)号：US20210401312A1

公开(公告)日：2021-12-30

申请号：US17469737

申请日：2021-09-08

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Tomoya NAKAZAWA ,  Rui SEKINE

IPC: A61B5/021 ,  A61B5/02 ,  A61B5/00 ,  A61B5/022 ,  A61B5/1455

Abstract: A viscoelastic characteristics acquisition device is a device that acquires viscoelastic characteristics of a blood vessel of an inspection target, and includes a pulse wave acquisition unit that acquires a time waveform corresponding to a volume pulse wave of the inspection target, a spectrum acquisition unit that acquires a volume pulse wave spectrum by performing Fourier transform on the time waveform, an input unit to which values corresponding to maximum blood pressure and minimum blood pressure of the inspection target are input, and an analysis unit that acquires the viscoelastic characteristics on the basis of the values corresponding to the maximum blood pressure and the minimum blood pressure and the volume pulse wave spectrum at a frequency equal to or higher than a frequency corresponding to the pulse of the inspection target.

公开(公告)号：US20170238816A1

公开(公告)日：2017-08-24

申请号：US15519868

申请日：2015-07-01

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Tomoya NAKAZAWA ,  Rui SEKINE

IPC: A61B5/021 ,  A61B5/024 ,  A61B5/00

CPC classification number: A61B5/02108 ,  A61B5/0075 ,  A61B5/022 ,  A61B5/02416 ,  A61B5/7235 ,  A61B5/7278 ,  A61B5/742

Abstract: A blood pressure measurement method of acquiring a change in a blood pressure with respect to time includes a pulse wave acquisition step of acquiring a time waveform based on a volume pulse wave, a DN point detection step of detecting a DN point, which corresponds to a dicrotic notch point in a blood pressure waveform indicating the change in the blood pressure with respect to time, in the time waveform, and a waveform correction step of correcting the time waveform so that a time waveform value at the DN point becomes a predetermined blood pressure value and acquiring the change in the blood pressure with respect to time.

公开(公告)号：US20180184919A1

公开(公告)日：2018-07-05

申请号：US15739864

申请日：2016-03-08

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Tomoya NAKAZAWA ,  Rui SEKINE

IPC: A61B5/021 ,  A61B5/022 ,  A61B5/00

CPC classification number: A61B5/02108 ,  A61B5/002 ,  A61B5/0059 ,  A61B5/02007 ,  A61B5/022 ,  A61B5/6898 ,  A61B5/7257

Abstract: A blood pressure ratio calculation device is a device for calculating a maximum-minimum blood pressure ratio corresponding to a ratio between a maximum blood pressure value and a minimum blood pressure value of an inspection target, and includes an input unit for inputting a relative blood pressure waveform corresponding to temporal change in relative blood pressure of the inspection target, a spectrum generation unit for generating a relative blood pressure waveform spectrum by performing Fourier transform on the relative blood pressure waveform, and an analysis unit for calculating the maximum-minimum blood pressure ratio on the basis of the relative blood pressure waveform spectrum.

公开(公告)号：US20200178858A1

公开(公告)日：2020-06-11

申请号：US16338550

申请日：2017-09-19

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Tomoya NAKAZAWA ,  Rui SEKINE ,  Masato KITABAYASHI ,  Anna IENAKA ,  Yu HASHIMOTO

IPC: A61B5/145 ,  A61B5/1455 ,  A61B5/00

Abstract: A blood glucose measurement device, a blood glucose calculation method, and a blood glucose calculation program capable of accurately measuring a blood glucose level by using light are provided. The blood glucose measurement device includes a light source 11 that outputs measurement light L1 to be input to a living body 50; a light detector 12 that detects the measurement light L1 propagated inside the living body 50 and generates a detection signal in accordance with an intensity of the measurement light L1; and a computation unit that obtains a time lag between a temporal change in a first parameter related to an oxygenated hemoglobin concentration and a temporal change in a second parameter related to a deoxygenated hemoglobin concentration based on the detection signal, and obtains the data related to the blood glucose level based on the time lag.

公开(公告)号：US20180353088A1

公开(公告)日：2018-12-13

申请号：US15778745

申请日：2016-03-30

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Tomoya NAKAZAWA ,  Rui SEKINE

IPC: A61B5/021 ,  A61B5/022 ,  A61B5/00

CPC classification number: A61B5/02108 ,  A61B5/0075 ,  A61B5/022 ,  A61B5/6814 ,  A61B5/6826 ,  A61B5/7207 ,  A61B5/7257

Abstract: A blood pressure information calculating device includes an input unit to which a waveform based on a pulse wave of the subject and reference blood pressure information serving as a reference for calculating the blood pressure information on the basis of the waveform based on the pulse wave are input, a conversion unit that calculates a phase spectrum of a waveform based on the pulse wave by performing Fourier transformation on the waveform based on the pulse wave, a calculation unit that calculates a correction value using at least one of a phase of a main wave corresponding to a pulse of the subject and a phase of a second harmonic wave of the main wave on the basis of the phase spectrum, and a calculation unit that calculates an average blood pressure by correcting the reference blood pressure information using the correction value.

公开(公告)号：US20240423537A1

公开(公告)日：2024-12-26

申请号：US18705020

申请日：2022-08-10

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Tomoya NAKAZAWA ,  Rui SEKINE ,  Masato KITABYASHI ,  Yu HASHIMOTO ,  Anna IENAKA

IPC: A61B5/00 ,  A61B5/145 ,  A61B5/1455

Abstract: A metabolism measurement apparatus includes, a photodetector that detects measurement light propagating through the living body and generates a detection signal according to an intensity of the measurement light, and a calculator. The calculator calculates a first parameter and a second parameter based on the detection signal. Each of the first parameter and the second parameter is a temporal relative change amount depending on a concentration of each of O2Hb and HHb in blood and a volume of a blood vessel in an optical path. The calculator obtains, based on the first parameter and the second parameter, a numerical value regarding a concentration of HHb in blood from which an influence of the volume of the blood vessel in the optical path is excluded. The calculator obtains data regarding a degree of metabolism based on the numerical value.

公开(公告)号：US20180184922A1

公开(公告)日：2018-07-05

申请号：US15739906

申请日：2016-03-08

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Tomoya NAKAZAWA ,  Rui SEKINE

IPC: A61B5/021 ,  A61B5/022 ,  A61B5/1455 ,  A61B5/00 ,  A61B5/02

CPC classification number: A61B5/02125 ,  A61B5/0059 ,  A61B5/02007 ,  A61B5/02108 ,  A61B5/022 ,  A61B5/14552 ,  A61B5/6801 ,  A61B5/6825 ,  A61B5/6898 ,  A61B5/7257

Abstract: A viscoelastic characteristics acquisition device is a device that acquires viscoelastic characteristics of a blood vessel of an inspection target, and includes a pulse wave acquisition unit that acquires a time waveform corresponding to a volume pulse wave of the inspection target, a spectrum acquisition unit that acquires a volume pulse wave spectrum by performing Fourier transform on the time waveform, an input unit to which values corresponding to maximum blood pressure and minimum blood pressure of the inspection target are input, and an analysis unit that acquires the viscoelastic characteristics on the basis of the values corresponding to the maximum blood pressure and the minimum blood pressure and the volume pulse wave spectrum at a frequency equal to or higher than a frequency corresponding to the pulse of the inspection target.