公开(公告)号：US20230078077A1

公开(公告)日：2023-03-16

申请号：US17800062

申请日：2021-01-05

Applicant: HAMAMATSU PHOTONICS K.K. ,  Social Welfare Corporation Seirei Social Welfare Community

Inventor： Kibo OTE ,  Fumio HASHIMOTO ,  Hidenao YAMADA ,  Akira OBANA

IPC: G06T5/00 ,  A61B3/12 ,  G06T5/50

Abstract: An ocular fundus image processing device acquires a first image generated by irradiating an ocular fundus of a subject with excitation light of a blue wavelength and a second image generated by irradiating the ocular fundus with excitation light of a green wavelength, generates three trained models for predicting a correction factor for calculating a quantity of macular pigment of the subject from input images including the first image and the second image through training using three different initial values, predicts three correction factors by inputting the input images including the first image and the second image to the three trained models, calculates a statistical value of the three correction factors and derives the statistical value as the correction factor of the subject, and calculates a quantity of macular pigment of the subject on the basis of the first image and the correction factor of the subject.

公开(公告)号：US20230072175A1

公开(公告)日：2023-03-09

申请号：US17795295

申请日：2021-01-26

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Fumio HASHIMOTO ,  Masanori ITO ,  Kibo OTE ,  Takashi ISOBE

IPC: G06T7/00 ,  G06V10/25 ,  G06V10/82

Abstract: A radiation tomography system includes a radiation tomography apparatus and an image processing apparatus. The image processing apparatus includes an image reconstruction unit, an attenuation distribution image creation unit, and an attenuation correction unit. The attenuation distribution image creation unit includes a first processing unit and a second processing unit. The first processing unit creates and outputs an intermediate image based on an emission scan image using a trained neural network. The second processing unit creates and outputs an attenuation distribution image based on the intermediate image.

公开(公告)号：US20230245478A1

公开(公告)日：2023-08-03

申请号：US18010545

申请日：2021-06-11

Applicant: HAMAMATSU PHOTONICS K.K. ,  NATIONAL UNIVERSITY CORPORATION HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE

Inventor： Fumio HASHIMOTO ,  Kibo OTE ,  Hidenao YAMADA ,  Hirotoshi KIKUCHI ,  Amane HIROTSU ,  Shigetoshi OKAZAKI

IPC: G06V20/69 ,  G06V10/40

CPC classification number: G06V20/698 ,  G06V10/40 ,  G06V2201/03

Abstract: A discrimination device is a device that discriminates whether or not a discrimination target object is a blood cell based on an image of the discrimination target object, and includes a blood cell feature extraction unit that acquires an image of a blood cell and extracts a feature of the blood cell from the acquired image, a discrimination target object feature extraction unit that acquires the image of the discrimination target object and extracts a feature of the discrimination target object from the acquired image, and a discrimination unit that discriminates whether or not the discrimination target object is a blood cell through anomaly detection based on the extracted feature of the blood cell and the feature of the discrimination target object.

公开(公告)号：US20220067332A1

公开(公告)日：2022-03-03

申请号：US17445773

申请日：2021-08-24

Applicant: Hamamatsu Photonics k.k.

Inventor： Kibo OTE ,  Fumio HASHIMOTO ,  Osamu YASUHIKO ,  Hidenao YAMADA

IPC: G06K9/00 ,  G06N20/00

Abstract: The method includes an acquisition step for model generation of acquiring a hologram for model generation in which an image of a cell is captured and which is used to generate a learning model, a generation step for model generation of generating a new hologram for model generation having a different focal position from the acquired hologram for model generation and increasing the number of holograms for model generation, and a learning model generation step of generating a learning model by performing machine learning using the increased holograms for model generation.

公开(公告)号：US20250079792A1

公开(公告)日：2025-03-06

申请号：US18844129

申请日：2023-03-06

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Kibo OTE ,  Yoshitaka KUROSAKA ,  Kazuyoshi HIROSE ,  Yuu TAKIGUCHI ,  Takahiro SUGIYAMA ,  Soh UENOYAMA

IPC: H01S5/042 ,  H01S5/22 ,  H01S5/223

Abstract: A semiconductor light-emitting element includes a semiconductor stacked layer, an electrode, and an electrode. The semiconductor stacked layer includes an active layer and a phase modulation layer. The phase modulation layer includes a plurality of phase modulation areas. Each of the plurality of phase modulation areas includes a basic region which has a first refractive index and a plurality of different-refractive-index regions which have a second refractive index different from the first refractive index and which are distributed in a two-dimensional shape. The electrode includes a plurality of electrode parts overlapping the plurality of phase modulation areas when seen in a stacking direction of the semiconductor stacked layer. The plurality of electrode parts are electrically isolated from each other. Laser light oscillating in each of the plurality of phase modulation areas is applied to a common irradiation area as light images according to arrangement of the plurality of different-refractive-index regions.

公开(公告)号：US20240366166A1

公开(公告)日：2024-11-07

申请号：US18683279

申请日：2022-08-18

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Yuya ONISHI ,  Ryosuke OTA ,  Fumio HASHIMOTO ,  Kibo OTE

IPC: A61B6/00 ,  A61B6/03 ,  A61B6/42 ,  G01T1/20

Abstract: A tomographic image creation apparatus includes a time difference calculation unit, a signal waveform processing unit, an error estimation unit, a γ-ray pair generation position calculation unit, and an image creation unit. The time difference calculation unit calculates, for each of γ-ray pair coincidence events, a time difference of a timing at which a value of each of a first signal and a second signal output from a signal waveform acquisition unit reaches a threshold value. The signal waveform processing unit relatively shifts a waveform of the first signal or a waveform of the second signal by the time difference in a direction approaching each other. The error estimation unit estimates an error of the time difference by a DNN based on the waveform of each of the first signal and the second signal after shifting.

公开(公告)号：US20220114772A1

公开(公告)日：2022-04-14

申请号：US17428693

申请日：2020-01-29

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Fumio HASHIMOTO ,  Kibo OTE

IPC: G06T11/00

Abstract: An image processing apparatus includes a first image creation unit, a second image creation unit, and a CNN processing unit. The first image creation unit creates a first tomographic image of an m-th frame using a data group in list data included in the m-th frame. The second image creation unit creates a second tomographic image using a data group in the list data having a data amount larger than that of the data group used in creating the first tomographic image. The CNN processing unit inputs the second tomographic image to a CNN, outputs an output tomographic image from the CNN, trains the CNN based on a comparison between the output tomographic image and the first tomographic image, and repeats the training operation to generate the output tomographic image in each training.