公开(公告)号：US20230078077A1

公开(公告)日：2023-03-16

申请号：US17800062

申请日：2021-01-05

Applicant: HAMAMATSU PHOTONICS K.K. ,  Social Welfare Corporation Seirei Social Welfare Community

Inventor： Kibo OTE ,  Fumio HASHIMOTO ,  Hidenao YAMADA ,  Akira OBANA

IPC: G06T5/00 ,  A61B3/12 ,  G06T5/50

Abstract: An ocular fundus image processing device acquires a first image generated by irradiating an ocular fundus of a subject with excitation light of a blue wavelength and a second image generated by irradiating the ocular fundus with excitation light of a green wavelength, generates three trained models for predicting a correction factor for calculating a quantity of macular pigment of the subject from input images including the first image and the second image through training using three different initial values, predicts three correction factors by inputting the input images including the first image and the second image to the three trained models, calculates a statistical value of the three correction factors and derives the statistical value as the correction factor of the subject, and calculates a quantity of macular pigment of the subject on the basis of the first image and the correction factor of the subject.

公开(公告)号：US20230245478A1

公开(公告)日：2023-08-03

申请号：US18010545

申请日：2021-06-11

Applicant: HAMAMATSU PHOTONICS K.K. ,  NATIONAL UNIVERSITY CORPORATION HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE

Inventor： Fumio HASHIMOTO ,  Kibo OTE ,  Hidenao YAMADA ,  Hirotoshi KIKUCHI ,  Amane HIROTSU ,  Shigetoshi OKAZAKI

IPC: G06V20/69 ,  G06V10/40

CPC classification number: G06V20/698 ,  G06V10/40 ,  G06V2201/03

Abstract: A discrimination device is a device that discriminates whether or not a discrimination target object is a blood cell based on an image of the discrimination target object, and includes a blood cell feature extraction unit that acquires an image of a blood cell and extracts a feature of the blood cell from the acquired image, a discrimination target object feature extraction unit that acquires the image of the discrimination target object and extracts a feature of the discrimination target object from the acquired image, and a discrimination unit that discriminates whether or not the discrimination target object is a blood cell through anomaly detection based on the extracted feature of the blood cell and the feature of the discrimination target object.

公开(公告)号：US20220067332A1

公开(公告)日：2022-03-03

申请号：US17445773

申请日：2021-08-24

Applicant: Hamamatsu Photonics k.k.

Inventor： Kibo OTE ,  Fumio HASHIMOTO ,  Osamu YASUHIKO ,  Hidenao YAMADA

IPC: G06K9/00 ,  G06N20/00

Abstract: The method includes an acquisition step for model generation of acquiring a hologram for model generation in which an image of a cell is captured and which is used to generate a learning model, a generation step for model generation of generating a new hologram for model generation having a different focal position from the acquired hologram for model generation and increasing the number of holograms for model generation, and a learning model generation step of generating a learning model by performing machine learning using the increased holograms for model generation.

公开(公告)号：US20230102661A1

公开(公告)日：2023-03-30

申请号：US17795566

申请日：2021-01-27

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Fumio HASHIMOTO

IPC: G06T11/00 ,  G06T5/00 ,  A61B6/00

Abstract: An image processing apparatus includes a feature extraction unit, a reconstruction unit, an evaluation unit, and a control unit. The feature extraction unit inputs an input image to a feature extraction NN, and outputs an intermediate image from the feature extraction NN. The reconstruction unit inputs the intermediate image to an m-th reconstruction NN, and outputs an m-th output image from the m-th reconstruction NN. The evaluation unit obtains an evaluation value based on a sum of differences between the m-th tomographic image and the m-th output image. The control unit repeatedly performs processes of the feature extraction unit and the reconstruction unit, calculation of the evaluation value by the evaluation unit, and training of the feature extraction NN and the m-th reconstruction NN based on the evaluation value.

公开(公告)号：US20230072175A1

公开(公告)日：2023-03-09

申请号：US17795295

申请日：2021-01-26

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Fumio HASHIMOTO ,  Masanori ITO ,  Kibo OTE ,  Takashi ISOBE

IPC: G06T7/00 ,  G06V10/25 ,  G06V10/82

Abstract: A radiation tomography system includes a radiation tomography apparatus and an image processing apparatus. The image processing apparatus includes an image reconstruction unit, an attenuation distribution image creation unit, and an attenuation correction unit. The attenuation distribution image creation unit includes a first processing unit and a second processing unit. The first processing unit creates and outputs an intermediate image based on an emission scan image using a trained neural network. The second processing unit creates and outputs an attenuation distribution image based on the intermediate image.

公开(公告)号：US20240366166A1

公开(公告)日：2024-11-07

申请号：US18683279

申请日：2022-08-18

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Yuya ONISHI ,  Ryosuke OTA ,  Fumio HASHIMOTO ,  Kibo OTE

IPC: A61B6/00 ,  A61B6/03 ,  A61B6/42 ,  G01T1/20

Abstract: A tomographic image creation apparatus includes a time difference calculation unit, a signal waveform processing unit, an error estimation unit, a γ-ray pair generation position calculation unit, and an image creation unit. The time difference calculation unit calculates, for each of γ-ray pair coincidence events, a time difference of a timing at which a value of each of a first signal and a second signal output from a signal waveform acquisition unit reaches a threshold value. The signal waveform processing unit relatively shifts a waveform of the first signal or a waveform of the second signal by the time difference in a direction approaching each other. The error estimation unit estimates an error of the time difference by a DNN based on the waveform of each of the first signal and the second signal after shifting.

公开(公告)号：US20220114772A1

公开(公告)日：2022-04-14

申请号：US17428693

申请日：2020-01-29

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Fumio HASHIMOTO ,  Kibo OTE

IPC: G06T11/00

Abstract: An image processing apparatus includes a first image creation unit, a second image creation unit, and a CNN processing unit. The first image creation unit creates a first tomographic image of an m-th frame using a data group in list data included in the m-th frame. The second image creation unit creates a second tomographic image using a data group in the list data having a data amount larger than that of the data group used in creating the first tomographic image. The CNN processing unit inputs the second tomographic image to a CNN, outputs an output tomographic image from the CNN, trains the CNN based on a comparison between the output tomographic image and the first tomographic image, and repeats the training operation to generate the output tomographic image in each training.