公开(公告)号：US20230136517A1

公开(公告)日：2023-05-04

申请号：US17912578

申请日：2021-03-23

Applicant: SEKISUI MEDICAL CO., LTD. ,  HAMAMATSU PHOTONICS K.K.

Inventor： Motoki MORITA ,  Keigo KOHNO ,  Daichi SUSUKI ,  Fusanori KONDO

IPC: G01N21/27 ,  G01N21/25

Abstract: An optical measurement device 1 includes: a measurement unit; and a determination unit, wherein the determination unit calculates a difference value between the initial measurement value and the latter measurement value when the measurement value exceeds the first threshold value after the sample is held by the lateral flow test strip, determines that the sample is positive when the difference value exceeds a second threshold value set in advance, and determines that the sample is negative when the difference value is the second threshold value or less.

公开(公告)号：US20230124819A1

公开(公告)日：2023-04-20

申请号：US17914434

申请日：2021-01-21

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Fusanori KONDO ,  Naoki IWATA ,  Tomokazu MATSUMURA ,  Teruo TAKESHITA

IPC: G01N21/27 ,  G01N21/47

Abstract: In an optical measurement device, in a first process, a reference member is irradiated with excitation light, light for a calibration process including scattered light associated with the excitation light from a reference member is detected as detection light, a calibration signal corresponding to the light for the calibration process is designated as a detection signal, and a calibration process for removing a signal component corresponding to the scattered light from the detection signal in a second process is performed. Also, in the optical measurement device, in the second process, a sample is irradiated with the excitation light, measurement target light including fluorescence generated from the sample and light scattered from the sample irradiated with the excitation light is detected as detection light, and a signal component corresponding to the scattered light from a measurement signal.

公开(公告)号：US20240102916A1

公开(公告)日：2024-03-28

申请号：US18274538

申请日：2021-10-15

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Hirohisa ONODA ,  Tomokazu MATSUMURA ,  Fusanori KONDO ,  Naokazu MORISHITA

IPC: G01N21/01

CPC classification number: G01N21/01 ,  G01N2021/6478

Abstract: An irradiation optical system configured to irradiate an object with first light includes: a light source including a surface emitting element emitting the first light from a light emitting surface; a light shaping member on which the first light emitted from the light source is incident via a light incidence surface and which shapes the incident first light using a light passing hole and emits the shaped first light; and a first lens configured to form an image of the first light emitted from the light shaping member on the object. A distance between the light emitting surface of the surface emitting element and the light incidence surface of the light shaping member is equal to or less than 26 times a size.

公开(公告)号：US20190187058A1

公开(公告)日：2019-06-20

申请号：US16098891

申请日：2017-02-23

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Yutaka HASEGAWA ,  Takayuki NAKAMURA ,  Yoshihiro ISHIGAMI ,  Fusanori KONDO

IPC: G01N21/64

CPC classification number: G01N21/6489 ,  G01N21/64 ,  G01N21/645 ,  G01N2201/127

Abstract: A reference body 1 includes: a support 10 provided with a first light passing portion 18, a second light passing portion 19, a first accommodating space 14, and a second accommodating space 15; a first fluorescent body 20 accommodated in the first accommodating space 14 and configured to emit first fluorescence in a second wavelength band when irradiated with first excitation light in a first wavelength band through the first light passing portion 18; a second fluorescent body 30 accommodated in the second accommodating space 15 and configured to emit second fluorescence in the second wavelength band when irradiated with second excitation light in the first wavelength band through the second light passing portion 19; and a light shielding portion 13 disposed between the first accommodating space 14 and the second accommodating space 15. In a case where a light amount of the first excitation light incident on the first light passing portion 18 and a light amount of the second excitation light incident on the second light passing portion 19 are equal to each other, a light amount of the first fluorescence emitted from the first light passing portion 18 and a light amount of the second fluorescence emitted from the second light passing portion 19 are different from each other.

公开(公告)号：US20240385265A1

公开(公告)日：2024-11-21

申请号：US18696064

申请日：2022-07-06

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Norihisa KATO ,  Masaki YAMADA ,  Fusanori KONDO

IPC: G01R33/26

Abstract: An optically pumped magnetometer module includes a housing and a cell unit disposed in the housing. The cell unit has a cell enclosing an alkali metal, a heat conductive member covering the cell, and a heater provided to the heat conductive member. The cell includes a main body portion having a light-passing region through which at least one of pump light and probe light passes. The heat conductive member is continuously provided over an entire region of an outer surface of the main body portion excluding the light-passing region.

公开(公告)号：US20230124033A1

公开(公告)日：2023-04-20

申请号：US17914445

申请日：2021-01-21

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Naoki IWATA ,  Fusanori KONDO ,  Tomokazu MATSUMURA ,  Teruo TAKESHITA

IPC: G01N21/64

Abstract: An optical measurement device includes an irradiation optical system, a detection optical system, and a cancel circuit. In a fluorescence detection process, a sample is designated as an irradiation target, the sample is irradiated with irradiation light, measurement target light including fluorescence generated from the sample irradiated with the irradiation light and light scattered from the sample irradiated with the irradiation light is detected as detection light, a signal component corresponding to the scattered light is removed from a measurement signal corresponding to the measurement target light in consideration of a result of performing a calibration process during a preliminary process. In the preliminary process, the calibration process for removing a signal component corresponding to the scattered light from the measurement signal is performed on the basis of a calibration signal having a higher signal intensity than a signal corresponding to the scattered light in the measurement signal.

公开(公告)号：US20210389249A1

公开(公告)日：2021-12-16

申请号：US17284279

申请日：2019-10-24

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Teruo TAKESHITA ,  Tomokazu MATSUMURA ,  Fusanori KONDO ,  Naoki IWATA

IPC: G01N21/64

Abstract: An optical measurement device includes a light detection element for detecting detection light including fluorescence generated from an immuno-chromatography test piece irradiated with excitation light and scattered light caused by the excitation light and having a phase equivalent to that of the excitation light, and a cancel circuit for processing a detection signal corresponding to the detection light. The cancel circuit removes a signal component corresponding to the scattered light from the detection signal on the basis of a phase difference between the fluorescence and the scattered light.