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公开(公告)号：US20060210539A1
公开(公告)日：2006-09-21
申请号：US11365390
申请日：2006-02-28
Applicant: H. Zhang , Philip Gregory
Inventor： H. Zhang , Philip Gregory
CPC classification number: C07K14/4705 , A61K38/00 , C07K14/4702 , C07K14/811 , C07K2319/71 , C07K2319/81 , C12N2799/022 , C12N2799/025 , C12N2799/028
Abstract: Disclosed herein are methods and compositions for treatment of conditions requiring inhibition of angiogenesis. Such conditions include those characterized by neovascularization, such as retinopathies, macular degeneration and various malignancies.
Abstract translation: 本文公开了用于治疗需要抑制血管发生的病症的方法和组合物。 这些病症包括以新生血管形成为特征，如视网膜病变，黄斑变性和各种恶性肿瘤。
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公开(公告)号：US20080108556A1
公开(公告)日：2008-05-08
申请号：US11981385
申请日：2007-10-31
Applicant: H. Zhang , Philip Gregory
Inventor： H. Zhang , Philip Gregory
IPC: A61K38/18
CPC classification number: C07K14/4705 , A61K38/00 , C07K14/4702 , C07K14/811 , C07K2319/71 , C07K2319/81 , C12N2799/022 , C12N2799/025 , C12N2799/028
Abstract: Disclosed herein are methods and compositions for treatment of conditions requiring inhibition of angiogenesis. Such conditions include those characterized by neovascularization, such as retinopathies, macular degeneration and various malignancies.
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公开(公告)号：US20080118469A1
公开(公告)日：2008-05-22
申请号：US11981386
申请日：2007-10-31
Applicant: H. Zhang , Philip Gregory
Inventor： H. Zhang , Philip Gregory
CPC classification number: C07K14/4705 , A61K38/00 , C07K14/4702 , C07K14/811 , C07K2319/71 , C07K2319/81 , C12N2799/022 , C12N2799/025 , C12N2799/028
Abstract: Disclosed herein are methods and compositions for treatment of conditions requiring inhibition of angiogenesis. Such conditions include those characterized by neovascularization, such as retinopathies, macular degeneration and various malignancies.
Abstract translation: 本文公开了用于治疗需要抑制血管发生的病症的方法和组合物。 这些病症包括以新生血管形成为特征，如视网膜病变，黄斑变性和各种恶性肿瘤。
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公开(公告)号：US20070134796A1
公开(公告)日：2007-06-14
申请号：US11493423
申请日：2006-07-26
Applicant: Michael Holmes , Fyodor Urnov , Philip Gregory , Edward Rebar , Sean Brennan
Inventor： Michael Holmes , Fyodor Urnov , Philip Gregory , Edward Rebar , Sean Brennan
IPC: C12N15/09
CPC classification number: C12N15/907 , A61K48/0008 , A61K48/005 , A61K48/0058 , C07K2319/00 , C07K2319/81 , C12N9/22 , C12N15/62 , C12N15/90
Abstract: Disclosed herein are methods and compositions for targeted integration of a exogenous sequence into a predetermined target site in a genome for use, for example, in protein expression and gene inactivation.
Abstract translation: 本文公开了用于将外源序列靶向整合到基因组中的预定靶位点以用于例如蛋白质表达和基因失活的方法和组合物。
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