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1.发明申请公开(公告)号：US20190248746A1
公开(公告)日：2019-08-15
申请号：US16391537
申请日：2019-04-23
发明人： Yingjie LAI
IPC分类号： C07D215/18 , A61P11/06 , A61K31/47
CPC分类号： C07D215/18 , A61K31/47 , A61P11/06
摘要： A cyclopropyl unsaturated quinoline compound used as leukotriene receptor antagonist and applications thereof, wherein the structural formula of the compound is as follows: An application of the compound or its pharmaceutically acceptable salts, hydrates, solvates, or prodrugs in preparing a drug for treating and/or preventing and/or delaying and/or providing adjuvant therapy for asthma and/or allergic rhinitis and asthma syndromes is provided. A drug composition includes the cyclopropyl unsaturated quinoline compound or the pharmaceutically acceptable salts, hydrates, solvates, or prodrugs thereof. The compound series has favorable foreground in preparing drugs for treating and/or preventing and/or delaying and/or providing adjuvant therapy for asthma and/or allergic rhinitis and asthma syndromes.
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2.发明申请公开(公告)号：US20180118687A1
公开(公告)日：2018-05-03
申请号：US15505040
申请日：2015-09-10
发明人： Yingjie LAI
IPC分类号： C07D215/18 , A61P11/06
CPC分类号： C07D215/18 , A61K31/47 , A61P11/06
摘要： A cyclopropyl unsaturated quinoline compound used as leukotriene receptor antagonist and applications thereof, wherein the structural formula of the compound is as follows: An application of the compound or its pharmaceutically acceptable salts, hydrates, solvates, or prodrugs in preparing a drug for treating and/or preventing and/or delaying and/or providing adjuvant therapy for asthma and/or allergic rhinitis and asthma syndromes is provided. A drug composition includes the cyclopropyl unsaturated quinoline compound or the pharmaceutically acceptable salts, hydrates, solvates, or prodrugs thereof. The compound series has favorable foreground in preparing the drugs for treating and/or preventing and/or delaying and/or providing adjuvant therapy for asthma and/or allergic rhinitis and asthma syndromes.
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