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公开(公告)号:US20240026392A1
公开(公告)日:2024-01-25
申请号:US18015046
申请日:2021-07-08
发明人: Kim Cecelia Anderson , Jeffrey Ian Boucher , Elena Brevnova , Brian Carvalho , Nicholas Flores , Katrina Forrest , Fiona Qu , Gabriel Rodrigues , Michelle Spencer
CPC分类号: C12P7/42 , C12P7/22 , C12N15/81 , C12Y121/03008 , C12Y404/01026 , C12Y205/0101 , C12Y203/01206 , C12N2800/102
摘要: Aspects of the disclosure relate to biosynthesis of cannabinoids and cannabinoid precursors in recombinant cells and in vitro, and to variant terminal synthases having altered catalytic activity to synthesize THC-type, CBD-type and/or CBC-type cannabinoids.
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公开(公告)号:US20220307060A1
公开(公告)日:2022-09-29
申请号:US17690446
申请日:2022-03-09
发明人: Kim Cecelia Anderson , Elena Brevnova , Dylan Alexander Carlin , Brian Carvalho , Nicholas Flores , Katrina Forrest , Matthew McMahon , Massimo Merighi , Gabriel Rodriguez , Emily E. Wrenbeck
摘要: Aspects of the disclosure relate to biosynthesis of cannabinoids and cannabinoid precursors in recombinant cells and in vitro.
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公开(公告)号:US20220195472A1
公开(公告)日:2022-06-23
申请号:US17665441
申请日:2022-02-04
发明人: Kim Cecelia Anderson , Elena Brevnova , Dylan Alexander Carlin , Brian Carvalho , Nicholas Flores , Katrina Forrest , Massimo Merighi , Gabriel Rodriguez , Emily E. Wrenbeck
摘要: Aspects of the disclosure relate to biosynthesis of cannabinoids and cannabinoid precursors in recombinant cells and in vitro.
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公开(公告)号:US20240110206A1
公开(公告)日:2024-04-04
申请号:US18031522
申请日:2021-10-12
发明人: Dylan Alexander Carlin , Brian Carvalho , Nicholas Flores , Katrina Forrest , Gabriel Rodriguez , Nathan W. Schmidt , Michelle Spencer
CPC分类号: C12P7/42 , C12N9/1029 , C12N9/1085 , C12N15/62 , C12N15/81 , C12Y203/01206 , C12Y205/0101
摘要: Aspects of the disclosure relate to biosynthesis of cannabinoids and cannabinoid precursors in recombinant cells and in vitro. Specifically, the disclosure is directed to a prenyltransferase variant, a chimeric prenyltransferase comprising one or more portions of at least two different prenyltransferase proteins, and a fusion polypeptide comprising a CBG-type producing prenyltransferase and farnesyl pyrophosphate synthase.
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公开(公告)号:US20230340446A1
公开(公告)日:2023-10-26
申请号:US18010666
申请日:2021-06-17
发明人: Kim Cecelia Anderson , Brian Carvalho , Nicholas Flores , Seth Ritter , Gabriel Rodriguez , Michelle Spencer , Emily E. Wrenbeck
CPC分类号: C12N9/88 , C12P7/42 , C12Y404/01026
摘要: Aspects of the disclosure relate to biosynthesis of cannabinoids and cannabinoid precursors in recombinant cells and in vitro. In particular, the disclosure relates to variants of olivetolic acid cyclase.
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公开(公告)号:US20230137139A1
公开(公告)日:2023-05-04
申请号:US17914060
申请日:2021-03-26
发明人: Kim Cecelia Anderson , Jeffrey lan Boucher , Elena Brevnova , Dylan Alexander Carlin , Brian Carvalho , Nicholas Flores , Katrina Forrest , Gabriel Rodriguez , Michelle Spencer
摘要: Aspects of the disclosure relate to biosynthesis of cannabinoids and cannabinoid precursors in recombinant cells and in vitro.
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公开(公告)号:US11274320B2
公开(公告)日:2022-03-15
申请号:US17078872
申请日:2020-10-23
发明人: Kim Cecelia Anderson , Elena Brevnova , Dylan Alexander Carlin , Brian Carvalho , Nicholas Flores , Katrina Forrest , Massimo Merighi , Gabriel Rodriguez , Emily E. Wrenbeck
摘要: Aspects of the disclosure relate to biosynthesis of cannabinoids and cannabinoid precursors in recombinant cells and in vitro.
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公开(公告)号:US20210071209A1
公开(公告)日:2021-03-11
申请号:US17078872
申请日:2020-10-23
发明人: Kim Cecelia Anderson , Elena Brevnova , Dylan Alexander Carlin , Brian Carvalho , Nicholas Flores , Katrina Forrest , Matthew McMahon , Massimo Merighi , Gabriel Rodriguez , Emily E. Wrenbeck
摘要: Aspects of the disclosure relate to biosynthesis of cannabinoids and cannabinoid precursors in recombinant cells and in vitro.
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