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公开(公告)号：US20210171499A1
公开(公告)日：2021-06-10
申请号：US17077729
申请日：2020-10-22
发明人： Stephen E. Ammann , Gediminas J. Brizgys , James S. Cassidy , Elbert Chin , Chienhung Chou , Jeromy J. Cottell , Michael Graupe , Chao-I Hung , Kavoos Kolahdouzan , Scott D. Schroeder , Nathan D. Shapiro , Daniel G. Shore , Suzanne M. Szewczyk , James G. Taylor , Rhiannon Thomas-Tran , Nathan E. Wright , Zheng-Yu Yang , Sheila M. Zipfel
IPC分类号： C07D401/14 , C07D401/10 , C07D409/14 , C07D235/16 , C07D403/06 , C07D405/14 , C07D471/04 , C07D493/08 , A61K45/06
摘要： The present disclosure provides GLP-1R agonists, and compositions, methods, and kits thereof. Such compounds are generally useful for treating a GLP-1R mediated disease or condition in a human.
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公开(公告)号：US20240116946A1
公开(公告)日：2024-04-11
申请号：US18376159
申请日：2023-10-03
发明人： Stephen E. Ammann , Xinpei Cai , Eda Y. Canales , Weng K. Chang , Gregory F. Chin , Henok H. Kinfe , Scott E. Lazerwith , Jessica L. McKinley , Michael R. Mish , Devan Naduthambi , Jason K. Perry , Kevin X. Rodriguez , Scott D. Schroeder , Christopher J. Swank , Joshua J. Van Veldhuizen
IPC分类号： C07D495/04 , C07D401/04 , C07D519/00
CPC分类号： C07D495/04 , C07D401/04 , C07D519/00
摘要： The present disclosure relates to compounds of Formula I:
and pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, useful in the treatment of treating viral infections, for example, coronaviridae infections.-
公开(公告)号：US11702404B2
公开(公告)日：2023-07-18
申请号：US17077729
申请日：2020-10-22
发明人： Stephen E. Ammann , Gediminas J. Brizgys , James S. Cassidy , Elbert Chin , Chienhung Chou , Jeromy J. Cottell , Michael Graupe , Chao-I Hung , Kavoos Kolahdouzan , Scott D. Schroeder , Nathan D. Shapiro , Daniel G. Shore , Suzanne M. Szewczyk , James G. Taylor , Rhiannon Thomas-Tran , Nathan E. Wright , Zheng-Yu Yang , Sheila M. Zipfel
IPC分类号： C07D401/10 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , A61K45/06 , C07D235/16 , C07D403/06 , C07D493/08
CPC分类号： C07D401/14 , A61K45/06 , C07D235/16 , C07D401/10 , C07D403/06 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D493/08
摘要： The present disclosure provides GLP-1R agonists, and compositions, methods, and kits thereof. Such compounds are generally useful for treating a GLP-1R mediated disease or condition in a human.
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公开(公告)号：US12091420B2
公开(公告)日：2024-09-17
申请号：US18376159
申请日：2023-10-03
发明人： Stephen E. Ammann , Xinpei Cai , Eda Y. Canales , Weng K. Chang , Gregory F. Chin , Henok H. Kinfe , Jessica L. Mckinley , Michael R. Mish , Devan Naduthambi , Jason K. Perry , Kevin X. Rodriguez , Scott D. Schroeder , Christopher J. Swank , Joshua J. Van Veldhuizen
IPC分类号： C07D495/04 , C07D401/04 , C07D519/00
CPC分类号： C07D495/04 , C07D401/04 , C07D519/00
摘要： The present disclosure relates to compounds of Formula I:
and pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, useful in the treatment of treating viral infections, for example, coronaviridae infections.-
公开(公告)号：US20240239807A1
公开(公告)日：2024-07-18
申请号：US18365919
申请日：2023-08-04
发明人： Stephen E. Ammann , Xinpei Cai , Eda Y. Canales , Weng K. Chang , Gregory F. Chin , Henok H. Kinfe , Scott E. Lazerwith , Jessica L. McKinley , Michael R. Mish , Devan Naduthambi , Jason K. Perry , Kevin X. Rodriguez , Scott D. Schroeder , Christopher J. Swank , Joshua J. Van Veldhuizen
IPC分类号： C07D495/04 , A61P31/14 , C07D401/04 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D487/04 , C07D487/10 , C07D491/107 , C07D491/113 , C07D498/04 , C07D513/04 , C07D519/00
CPC分类号： C07D495/04 , A61P31/14 , C07D401/04 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D487/04 , C07D487/10 , C07D491/107 , C07D491/113 , C07D498/04 , C07D513/04 , C07D519/00
摘要： The present disclosure relates to compounds of Formula I:
and pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, useful in the treatment of treating viral infections, for example, coronaviridae infections.-
公开(公告)号：US20230391747A1
公开(公告)日：2023-12-07
申请号：US18195767
申请日：2023-05-10
发明人： Stephen E. Ammann , Gediminas J. Brizgys , James S. Cassidy , Elbert Chin , Chienhung Chou , Jeromy J. Cottell , Michael Graupe , Chao-I Hung , Kavoos Kolahdouzan , Scott D. Schroeder , Nathan D. Shapiro , Daniel G. Shore , Suzanne M. Szewczyk , James G. Taylor , Rhiannon Thomas-Tran , Nathan E. Wright , Zheng-Yu Yang , Sheila M. Zipfel
IPC分类号： C07D401/14 , A61K45/06 , C07D235/16 , C07D401/10 , C07D403/06 , C07D405/14 , C07D409/14 , C07D471/04 , C07D493/08 , C07D413/14 , C07D417/14
CPC分类号： C07D401/14 , A61K45/06 , C07D235/16 , C07D401/10 , C07D403/06 , C07D405/14 , C07D409/14 , C07D471/04 , C07D493/08 , C07D413/14 , C07D417/14
摘要： The present disclosure provides GLP-1R agonists, and compositions, methods, and kits thereof. Such compounds are generally useful for treating a GLP-1R mediated disease or condition in a human.
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公开(公告)号：US20220288030A1
公开(公告)日：2022-09-15
申请号：US17159485
申请日：2021-01-27
发明人： Stephen E. Ammann , Gediminas J. Brizgys , James S. Cassidy , Elbert Chin , Chienhung Chou , Jeromy J. Cottell , Chao-I Hung , Kavoos Kolahdouzan , Daniel G. Shore , Suzanne M. Szewczyk , James G. Taylor , Rhiannon Thomas-Tran , Nathan E. Wright , Zheng-Yu Yang
IPC分类号： A61K31/4184 , A61K45/06 , C07D405/10 , C07D405/14 , C07D409/14 , C07D413/10 , C07D498/04 , C07D471/04 , C07D493/04 , C07D493/10 , A61K31/424 , A61K31/437 , A61K31/444 , A61K31/4439 , A61K31/4192 , A61K31/4196 , A61K31/422
摘要： The present disclosure provides GLP-1R agonists, and compositions, methods, and kits thereof. Such compounds are generally useful for treating a GLP-1R mediated disease or condition.
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公开(公告)号：US12121511B2
公开(公告)日：2024-10-22
申请号：US17159485
申请日：2021-01-27
发明人： Stephen E. Ammann , Gediminas J. Brizgys , James S. Cassidy , Elbert Chin , Chienhung Chou , Jeromy J. Cottell , Chao-I Hung , Kavoos Kolahdouzan , Daniel G. Shore , Suzanne M. Szewczyk , James G. Taylor , Rhiannon Thomas-Tran , Nathan E. Wright , Zheng-Yu Yang
IPC分类号： A61K31/4184 , A61K31/4192 , A61K31/4196 , A61K31/422 , A61K31/424 , A61K31/437 , A61K31/4439 , A61K31/444 , A61K45/06 , C07D405/10 , C07D405/14 , C07D409/14 , C07D413/10 , C07D471/04 , C07D493/04 , C07D493/10 , C07D498/04
CPC分类号： A61K31/4184 , A61K31/4192 , A61K31/4196 , A61K31/422 , A61K31/424 , A61K31/437 , A61K31/4439 , A61K31/444 , A61K45/06 , C07D405/10 , C07D405/14 , C07D409/14 , C07D413/10 , C07D471/04 , C07D493/04 , C07D493/10 , C07D498/04
摘要： The present disclosure provides GLP-1R agonists, and compositions, methods, and kits thereof. Such compounds are generally useful for treating a GLP-1R mediated disease or condition.
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公开(公告)号：US20240217990A1
公开(公告)日：2024-07-04
申请号：US18264670
申请日：2022-02-08
发明人： Stephen E. Ammann , Eda Y. Canales , Weng K. Chang , Julian A. Codelli , Lan Jiang , Henok H. Kinfe , Scott E. Lazerwith , Michael L. Mitchell , Scott D. Schroeder , Daniel G. Shore
IPC分类号： C07D519/00 , A61K31/437 , A61K31/438 , A61K31/4439 , A61K31/444 , A61K31/4545
CPC分类号： C07D519/00 , A61K31/437 , A61K31/438 , A61K31/4439 , A61K31/444 , A61K31/4545
摘要： The present disclosure relates generally to certain compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions provided herein may be used for the treatment or prevention of an autoimmune disease and/or inflammatory condition, including systemic lupus erythematosus and cutaneous lupus erythematosus.
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公开(公告)号：US20230365594A1
公开(公告)日：2023-11-16
申请号：US18180438
申请日：2023-03-08
发明人： Stephen E. Ammann , Eda Y. Canales , Weng K. Chang , Henok H. Kinfe , Scott E. Lazerwith , Michael L. Mitchell , Yasamin Moazami , Scott D. Schroeder , Daniel G. Shore , Christopher J. Swank
IPC分类号： C07D519/00 , C07D495/04
CPC分类号： C07D519/00 , C07D495/04
摘要： The present disclosure relates generally to certain compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions provided herein may be used for the treatment or prevention of an autoimmune disease and/or inflammatory condition, including systemic lupus erythematosus and cutaneous lupus erythematosus.
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