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公开(公告)号：US12180197B2
公开(公告)日：2024-12-31
申请号：US17690851
申请日：2022-03-09
Applicant: Gilead Sciences, Inc.
Inventor： Gediminas J. Brizgys , Chienhung Chou , Jeromy J. Cottell , Chao-I Hung , Michael L. Mitchell , Scott D. Schroeder , Nathan D. Shapiro , Suzanne M. Szewczyk , James G. Taylor , Nathan E. Wright , Sheila M. Zipfel
IPC: C07D405/14 , A61K31/4545 , A61K31/4725 , A61K45/06 , C07D401/14 , C07D413/14 , C07D417/14
Abstract: The present disclosure provides GLP-1R agonists, and compositions, methods, and kits thereof. Such compounds are generally useful for treating a GLP-1R mediated disease or condition in a human.
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公开(公告)号：US11858918B2
公开(公告)日：2024-01-02
申请号：US17724212
申请日：2022-04-19
Applicant: Gilead Sciences, Inc.
Inventor： Megan K. Armstrong , James S. Cassidy , Elbert Chin , Chienhung Chou , Jeromy J. Cottell , Chao-I Hung , Kavoos Kolahdouzan , David W. Lin , Michael L. Mitchell , Ezra Roberts , Scott D. Schroeder , Nathan D. Shapiro , James G. Taylor , Rhiannon Thomas-Tran , Nathan E. Wright , Zheng-Yu Yang
IPC: C07D405/14 , A61K31/437 , A61K31/4439 , A61K31/497 , A61K31/506 , A61K31/5377 , A61K31/675 , C07D401/08 , C07D401/10 , C07D401/14 , C07D409/14 , C07D417/14 , C07D471/04 , C07D491/048 , C07D493/08 , C07D493/10 , C07F9/6558
CPC classification number: C07D405/14 , A61K31/437 , A61K31/4439 , A61K31/497 , A61K31/506 , A61K31/5377 , A61K31/675 , C07D401/08 , C07D401/10 , C07D401/14 , C07D409/14 , C07D417/14 , C07D471/04 , C07D491/048 , C07D493/08 , C07D493/10 , C07F9/65586
Abstract: The present disclosure provides GLP-1R agonists, and compositions, methods, and kits thereof. Such compounds are generally useful for treating a GLP-1R mediated disease or condition in a human.
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公开(公告)号：US20210171499A1
公开(公告)日：2021-06-10
申请号：US17077729
申请日：2020-10-22
Applicant: Gilead Sciences, Inc.
Inventor： Stephen E. Ammann , Gediminas J. Brizgys , James S. Cassidy , Elbert Chin , Chienhung Chou , Jeromy J. Cottell , Michael Graupe , Chao-I Hung , Kavoos Kolahdouzan , Scott D. Schroeder , Nathan D. Shapiro , Daniel G. Shore , Suzanne M. Szewczyk , James G. Taylor , Rhiannon Thomas-Tran , Nathan E. Wright , Zheng-Yu Yang , Sheila M. Zipfel
IPC: C07D401/14 , C07D401/10 , C07D409/14 , C07D235/16 , C07D403/06 , C07D405/14 , C07D471/04 , C07D493/08 , A61K45/06
Abstract: The present disclosure provides GLP-1R agonists, and compositions, methods, and kits thereof. Such compounds are generally useful for treating a GLP-1R mediated disease or condition in a human.
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公开(公告)号：US20220298148A1
公开(公告)日：2022-09-22
申请号：US17690889
申请日：2022-03-09
Applicant: Gilead Sciences, Inc.
Inventor： Gediminas J. Brizgys , Chienhung Chou , Jeromy J. Cottell , Chao-I Hung , Michael L. Mitchell , James G. Taylor , Rhiannon Thomas-Tran , Nathan E. Wright , Zheng-Yu Yang , Sheila M. Zipfel
IPC: C07D409/14 , A61P1/16 , A61K45/06 , A61K31/4545 , C07D417/14 , C07D405/14
Abstract: The present disclosure provides GLP-1R agonists, and compositions, methods, and kits thereof. Such compounds are generally useful for treating a GLP-1R mediated disease or condition in a human.
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公开(公告)号：US20220177449A1
公开(公告)日：2022-06-09
申请号：US17530300
申请日：2021-11-18
Applicant: Gilead Sciences, Inc.
Inventor： Gediminas J. Brizgys , James S. Cassidy , Chienhung Chou , Jeromy J. Cottell , Chao-I Hung , Kavoos Kolahdouzan , James G. Taylor , Nathan E. Wright , Zheng-Yu Yang
IPC: C07D401/14 , C07D405/14 , A61K45/06
Abstract: The present disclosure provides GLP-1R agonists, and compositions, methods, and kits thereof. Such compounds are generally useful for treating a GLP-1R mediated disease or condition in a human.
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Patent Agency Ranking
公开(公告)号：US12091404B2
公开(公告)日：2024-09-17
申请号：US17690889
申请日：2022-03-09
Applicant: Gilead Sciences, Inc.
Inventor： Gediminas J. Brizgys , Chienhung Chou , Jeromy J. Cottell , Chao-I Hung , Michael L. Mitchell , James G. Taylor , Rhiannon Thomas-Tran , Nathan E. Wright , Zheng-Yu Yang , Sheila M. Zipfel
IPC: A61K31/4545 , A61K31/4439 , A61K45/06 , A61P1/16 , C07D211/14 , C07D405/14 , C07D409/14 , C07D417/14
CPC classification number: C07D409/14 , A61K31/4545 , A61K45/06 , A61P1/16 , C07D405/14 , C07D417/14 , C07D211/14
Abstract: The present disclosure provides GLP-1R agonists, and compositions, methods, and kits thereof. Such compounds are generally useful for treating a GLP-1R mediated disease or condition in a human.
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公开(公告)号：US11702404B2
公开(公告)日：2023-07-18
申请号：US17077729
申请日：2020-10-22
Applicant: Gilead Sciences, Inc.
Inventor： Stephen E. Ammann , Gediminas J. Brizgys , James S. Cassidy , Elbert Chin , Chienhung Chou , Jeromy J. Cottell , Michael Graupe , Chao-I Hung , Kavoos Kolahdouzan , Scott D. Schroeder , Nathan D. Shapiro , Daniel G. Shore , Suzanne M. Szewczyk , James G. Taylor , Rhiannon Thomas-Tran , Nathan E. Wright , Zheng-Yu Yang , Sheila M. Zipfel
IPC: C07D401/10 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , A61K45/06 , C07D235/16 , C07D403/06 , C07D493/08
CPC classification number: C07D401/14 , A61K45/06 , C07D235/16 , C07D401/10 , C07D403/06 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D493/08
Abstract: The present disclosure provides GLP-1R agonists, and compositions, methods, and kits thereof. Such compounds are generally useful for treating a GLP-1R mediated disease or condition in a human.
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公开(公告)号：US20220306614A1
公开(公告)日：2022-09-29
申请号：US17690851
申请日：2022-03-09
Applicant: Gilead Sciences, Inc.
Inventor： Gediminas J. Brizgys , Chienhung Chou , Jeromy J. Cottell , Chao-I Hung , Michael L. Mitchell , Scott D. Schroeder , Nathan D. Shapiro , Suzanne M. Szewczyk , James G. Taylor , Nathan E. Wright , Sheila M. Zipfel
IPC: C07D405/14 , A61K31/4545 , A61K45/06 , C07D401/14 , A61K31/4725 , C07D413/14 , C07D417/14
Abstract: The present disclosure provides GLP-1R agonists, and compositions, methods, and kits thereof. Such compounds are generally useful for treating a GLP-1R mediated disease or condition in a human.
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公开(公告)号：US20240254118A1
公开(公告)日：2024-08-01
申请号：US18391258
申请日：2023-12-20
Applicant: Gilead Sciences, Inc.
Inventor： Megan K. Armstrong , Elbert Chin , Chienhung Chou , Laurent P. Debien , Joshua D. Farr , Pancham Lal Gupta , Chao-I Hung , Michael L. Mitchell , Prasenjit K. Mukherjee , Shaina V. Nguyen , Gregory T. Notte , Daniel Roa , Adam J. Schrier , Zheng-Yu Yang
IPC: C07D471/04 , A61K31/473 , A61K31/4741 , A61K31/4743 , A61K31/4745 , A61K31/4748 , A61K31/496 , A61K31/501 , A61K31/506 , A61K31/5355 , A61K31/5377 , A61K31/5386 , A61K31/541 , A61K31/55 , C07D401/12 , C07D491/048 , C07D513/04 , C07D519/00
CPC classification number: C07D471/04 , A61K31/473 , A61K31/4741 , A61K31/4743 , A61K31/4745 , A61K31/4748 , A61K31/496 , A61K31/501 , A61K31/506 , A61K31/5355 , A61K31/5377 , A61K31/5386 , A61K31/541 , A61K31/55 , C07D401/12 , C07D491/048 , C07D513/04 , C07D519/00
Abstract: The present disclosure relates generally to compounds that inhibit PRMT5. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through inhibiting PRMT5. The disclosure further relates to the use of the compounds for the treatment of a disease or condition associated with chromosome 9p21 deletion or MTAP null. The disclosure further relates to the use of the compounds for the treatment of cancers.
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公开(公告)号：US11851419B2
公开(公告)日：2023-12-26
申请号：US17530300
申请日：2021-11-18
Applicant: Gilead Sciences, Inc.
Inventor： Gediminas J. Brizgys , James S. Cassidy , Chienhung Chou , Jeromy J. Cottell , Chao-I Hung , Kavoos Kolahdouzan , James G. Taylor , Nathan E. Wright , Zheng-Yu Yang
IPC: C07D401/14 , A61K45/06 , C07D405/14
CPC classification number: C07D401/14 , A61K45/06 , C07D405/14
Abstract: The present disclosure provides GLP-1R agonists, and compositions, methods, and kits thereof. Such compounds are generally useful for treating a GLP-1R mediated disease or condition in a human.
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