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公开(公告)号:US10035854B2
公开(公告)日:2018-07-31
申请号:US15349757
申请日:2016-11-11
Applicant: Genentech, Inc.
Inventor: Yan Wu , Weilan Ye , Jeremy Bryant Burton , Cecilia Chiu
CPC classification number: C07K16/28 , A61K39/395 , A61K47/6849 , A61K2039/505 , A61P9/10 , A61P27/02 , C07H21/04 , C07K2317/21 , C07K2317/24 , C07K2317/56 , C07K2317/567 , C07K2317/75 , C07K2317/92
Abstract: The invention provides anti-LRP5 antibodies and methods of making and using the same.
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公开(公告)号:US20170166636A1
公开(公告)日:2017-06-15
申请号:US15349757
申请日:2016-11-11
Applicant: Genentech, Inc.
Inventor: Yan Wu , Weilan Ye , Jeremy Bryant Burton , Cecilia Chiu
IPC: C07K16/28
CPC classification number: C07K16/28 , A61K39/395 , A61K47/6849 , A61K2039/505 , A61P9/10 , A61P27/02 , C07H21/04 , C07K2317/21 , C07K2317/24 , C07K2317/56 , C07K2317/567 , C07K2317/75 , C07K2317/92
Abstract: The invention provides anti-LRP5 antibodies and methods of making and using the same.
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3.
公开(公告)号:US08574576B2
公开(公告)日:2013-11-05
申请号:US13668129
申请日:2012-11-02
Applicant: Genentech, Inc.
Inventor: Weilan Ye , Mark S. Dennis , Jill Fredrickson
IPC: A61K39/395
CPC classification number: C07K16/22 , A61K31/282 , A61K31/337 , A61K31/513 , A61K31/519 , A61K31/555 , A61K31/56 , A61K38/19 , A61K39/0011 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/18 , C07K16/46 , C07K16/468 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92
Abstract: The present invention concerns antibodies to EGFL7 and the uses of same.
Abstract translation: 本发明涉及EGFL7的抗体及其用途。
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公开(公告)号:US20130064822A1
公开(公告)日:2013-03-14
申请号:US13668129
申请日:2012-11-02
Applicant: Genentech, Inc.
Inventor: Weilan Ye , Mark S. Dennis , Jill Fredrickson
CPC classification number: C07K16/22 , A61K31/282 , A61K31/337 , A61K31/513 , A61K31/519 , A61K31/555 , A61K31/56 , A61K38/19 , A61K39/0011 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/18 , C07K16/46 , C07K16/468 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92
Abstract: The present invention concerns antibodies to EGFL7 and the uses of same.
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5.
公开(公告)号:US20140051120A1
公开(公告)日:2014-02-20
申请号:US13668054
申请日:2012-11-02
Applicant: Genentech, Inc.
Inventor: Weilan Ye , Mark S. Dennis , Jill Fredrickson
IPC: C07K16/22
CPC classification number: C07K16/22 , A61K31/282 , A61K31/337 , A61K31/513 , A61K31/519 , A61K31/555 , A61K31/56 , A61K38/19 , A61K39/0011 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/18 , C07K16/46 , C07K16/468 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92
Abstract: The present invention concerns antibodies to EGFL7 and the uses of same.
Abstract translation: 本发明涉及EGFL7的抗体及其用途。
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公开(公告)号:US20130129733A1
公开(公告)日:2013-05-23
申请号:US13668064
申请日:2012-11-02
Applicant: Genentech, Inc.
Inventor: Weilan Ye , Mark S. Dennis , Jill Fredrickson
IPC: C07K16/18 , A61K31/555 , A61K31/56 , A61K38/19 , A61K39/395 , A61K45/06
CPC classification number: C07K16/22 , A61K31/282 , A61K31/337 , A61K31/513 , A61K31/519 , A61K31/555 , A61K31/56 , A61K38/19 , A61K39/0011 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/18 , C07K16/46 , C07K16/468 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92
Abstract: The present invention concerns antibodies to EGFL7 and the uses of same.
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公开(公告)号:US20130149307A1
公开(公告)日:2013-06-13
申请号:US13668028
申请日:2012-11-02
Applicant: Genentech, Inc.
Inventor: Weilan Ye , Mark S. Dennis , Jill Fredrickson
IPC: C07K16/18 , A61K39/395 , A61K45/06 , A61K39/00 , A61K31/519 , A61K38/19 , A61K31/555 , A61K31/337 , A61K31/513 , C07K16/22 , A61K31/56
CPC classification number: C07K16/22 , A61K31/282 , A61K31/337 , A61K31/513 , A61K31/519 , A61K31/555 , A61K31/56 , A61K38/19 , A61K39/0011 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/18 , C07K16/46 , C07K16/468 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92
Abstract: The present invention concerns antibodies to EGFL7 and the uses of same.
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公开(公告)号:US20130129749A1
公开(公告)日:2013-05-23
申请号:US13668086
申请日:2012-11-02
Applicant: Genentech, Inc.
Inventor: Weilan Ye , Mark S. Dennis , Jill Fredrickson
IPC: C07K16/18 , A61K31/337 , A61K31/282 , A61K39/395 , A61K31/513
CPC classification number: C07K16/22 , A61K31/282 , A61K31/337 , A61K31/513 , A61K31/519 , A61K31/555 , A61K31/56 , A61K38/19 , A61K39/0011 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/18 , C07K16/46 , C07K16/468 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92
Abstract: The present invention concerns antibodies to EGFL7 and the uses of same.
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公开(公告)号:US09522954B2
公开(公告)日:2016-12-20
申请号:US14879702
申请日:2015-10-09
Applicant: Genentech Inc.
Inventor: Yan Wu , Weilan Ye , Jeremy Bryant Burton , Cecilia Chiu
IPC: C07H21/04 , C07K16/28 , A61K39/395 , A61P27/02 , A61K39/00
CPC classification number: C07K16/28 , A61K39/395 , A61K47/6849 , A61K2039/505 , A61P9/10 , A61P27/02 , C07H21/04 , C07K2317/21 , C07K2317/24 , C07K2317/56 , C07K2317/567 , C07K2317/75 , C07K2317/92
Abstract: The invention provides anti-LRP5 antibodies and methods of making and using the same.
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10.TREATMENT OF DISORDERS WITH ALTERED VASCULAR BARRIER FUNCTION 审中-公开
Title translation: 用改进的血管阻滞功能治疗疾病公开(公告)号:US20140005113A1
公开(公告)日:2014-01-02
申请号:US14022475
申请日:2013-09-10
Applicant: Genentech, Inc.
Inventor: Weilan Ye , Leon H. Parker, IV , Christopher W. Wilson
IPC: A61K38/02 , C12N15/113
CPC classification number: A61K38/02 , A61K31/00 , A61K31/7105 , C12N15/113
Abstract: The present invention provides methods of using RASIP1 agonists and antagonists to modulate vascular barrier function and regulate new vessel formation, and to treat related disorders.
Abstract translation: 本发明提供了使用RASIP1激动剂和拮抗剂调节血管屏障功能并调节新血管形成以及治疗相关疾病的方法。
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