公开(公告)号：US11066389B2

公开(公告)日：2021-07-20

申请号：US16718602

申请日：2019-12-18

Applicant: Genentech, Inc.

Inventor： Jinguang Lin ,  Alexandra Chestakova ,  Wei Gu ,  Hans Iding ,  Jing Li ,  Xin Linghu ,  Patrik Meier ,  Chunbo Sha ,  Jeffrey Stults ,  Youchu Wang ,  Haiming Zhang ,  Jianqian Zhang ,  Tao Zhang

IPC: C07D401/14 ,  C07D401/04 ,  A61P35/00 ,  A61P25/00 ,  A61P29/00 ,  C12P17/16

Abstract: The present invention provides a process for the manufacture of a compound of formula VIIIa and salts forms of VIIIa where Rc is an aryl sulfonic acid

公开(公告)号：US11098028B2

公开(公告)日：2021-08-24

申请号：US16535752

申请日：2019-08-08

Applicant: Genentech, Inc.

Inventor： Jinguang Lin ,  Alexandra Chestakova ,  Wei Gu ,  Hans Iding ,  Jing Li ,  Xin Linghu ,  Patrik Meier ,  Chunbo Sha ,  Jeffrey Stults ,  Youchu Wang ,  Haiming Zhang ,  Jianqian Zhang ,  Tao Zhang

IPC: C07D401/14 ,  C07D401/04 ,  C12P17/16 ,  A61P35/00 ,  A61P25/00 ,  A61P29/00

Abstract: The present invention provides a process for the manufacture of a compound of formula VIIIa and salts forms of VIIIa where Rc is an aryl sulfonic acid

公开(公告)号：US20180134685A1

公开(公告)日：2018-05-17

申请号：US15866899

申请日：2018-01-10

Applicant: Genentech, Inc.

Inventor： Jinguang Lin ,  Alexandra Chestakova ,  Wei Gu ,  Hans Iding ,  Jing Li ,  Xin Linghu ,  Patrik Meier ,  Chunbo Sha ,  Jeffrey Stults ,  Youchu Wang ,  Haiming Zhang ,  Jianqian Zhang ,  Tao Zhang

IPC: C07D401/14 ,  C07D401/04 ,  C12P17/16

CPC classification number: C07D401/14 ,  A61P25/00 ,  A61P29/00 ,  A61P35/00 ,  C07D401/04 ,  C12P17/165

Abstract: The present invention provides a process for the manufacture of a compound of formula VIIIa and salts forms of VIIIa where Rc is an aryl sulfonic acid

公开(公告)号：US20170022183A1

公开(公告)日：2017-01-26

申请号：US15285781

申请日：2016-10-05

Applicant: Genentech, Inc.

Inventor： Jinguang Lin ,  Alexandra Chestakova ,  Wei Gu ,  Hans Iding ,  Jing Li ,  Xin Linghu ,  Patrik Meier ,  Chunbo Sha ,  Jeffrey Stults ,  Youchu Wang ,  Haiming Zhang ,  Jianqian Zhang ,  Tao Zhang

IPC: C07D401/14 ,  C12P17/16 ,  C07D401/04

CPC classification number: C07D401/14 ,  A61P25/00 ,  A61P29/00 ,  A61P35/00 ,  C07D401/04 ,  C12P17/165

Abstract: The present invention provides a process for the manufacture of a compound of formula VIIIa and salts forms of VIIIa where Rc is an aryl sulfonic acid

Abstract translation: 本发明提供了制备式（Ⅷa）化合物和（Ⅷa）盐形式的方法，其中Rc是芳基磺酸。