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1.METHODS OF TREATING HER2-POSITIVE CANCERS USING PD-1 AXIS BINDING ANTAGONISTS AND ANTI-HER2 ANTIBODIES 审中-公开
Title translation: 使用PD-1轴结合拮抗剂和抗HER2抗体治疗HER2阳性癌症的方法公开(公告)号:US20170008971A1
公开(公告)日:2017-01-12
申请号:US15184966
申请日:2016-06-16
Applicant: Genentech, Inc.
Inventor: Mark S. DENNIS , Allen EBENS , Bryan IRVING , Teemu T. JUNTTILA , Ji LI
IPC: C07K16/32 , A61K39/395 , A61K45/06 , C07K16/28 , C07K16/30
CPC classification number: C07K16/32 , A61K31/282 , A61K31/337 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K47/643 , A61K2039/505 , A61K2039/507 , C07K16/2803 , C07K16/2809 , C07K16/2818 , C07K16/2827 , C07K16/30 , C07K16/3015 , C07K16/3023 , C07K16/303 , C07K16/3038 , C07K16/3069 , C07K2317/24 , C07K2317/31 , C07K2317/41 , C07K2317/52 , C07K2317/524 , C07K2317/526 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2317/94 , A61K2300/00
Abstract: The invention provides compositions and methods for treating HER2-postitive cancers. The method comprising administering a PD-1 axis binding antagonist and an antibody that targets HER2.
Abstract translation: 本发明提供用于治疗HER2-肿瘤的组合物和方法。 该方法包括施用PD-1轴结合拮抗剂和靶向HER2的抗体。