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Patent Agency Ranking
公开(公告)号：US12013401B2
公开(公告)日：2024-06-18
申请号：US18142538
申请日：2023-05-02
Applicant: GenNext Technologies, Inc.
Inventor： Scot Randy Weinberger , Ronald Carl Orlando , Joshua Shane Sharp , Robert Wallace Egan , Jeffrey Jonathan Persoff
CPC classification number: G01N33/6803 , C23C18/14 , G01N21/59 , G01N21/631 , G01N21/6428 , H01J49/0036 , G01N2021/6439
Abstract: Flash Photo-Oxidation Device and Higher Order Structural Analysis is employed for higher order structural analysis of biomolecules. Biomolecular higher order structure (HOS) results from the confounded superimposition of a biomolecule's secondary, tertiary, and quaternary structure and defines the manner in which a biomolecule presents itself and interacts with other biomolecules in living systems. A rapidly growing class of therapeutic drugs, known as biotherapeutics, comprises a variety of proteins, whose therapeutic properties are inherently linked and dependent upon their HOS. As such, HOS analysis of biotherapeutics is an important analytical requirement in the biopharmaceutical industry. The present invention provides new means and methods for the determination of biopharmaceutical HOS and associated conformation using improved devices and methodologies for flash photo-oxidation of proteins to determine their higher order biomolecular structure, and such is responsive to the increased demand for new and improved HOS analytical means in the biopharmaceutical industry.
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公开(公告)号：US12013400B2
公开(公告)日：2024-06-18
申请号：US17168472
申请日：2021-02-05
Applicant: GenNext Technologies, Inc.
Inventor： Scot Randy Weinberger , Ronald Carl Orlando , Joshua Shane Sharp , Robert Wallace Egan , Jeffrey Jonathan Persoff
CPC classification number: G01N33/6803 , C23C18/14 , G01N21/59 , G01N21/631 , G01N21/6428 , H01J49/0036 , G01N2021/6439
Abstract: Flash Photo-Oxidation Device and Higher Order Structural Analysis is employed for higher order structural analysis of biomolecules. Biomolecular higher order structure (HOS) results from the confounded superimposition of a biomolecule's secondary, tertiary, and quaternary structure and defines the manner in which a biomolecule presents itself and interacts with other biomolecules in living systems. A rapidly growing class of therapeutic drugs, known as biotherapeutics, comprises a variety of proteins, whose therapeutic properties are inherently linked and dependent upon their HOS. As such, HOS analysis of biotherapeutics is an important analytical requirement in the biopharmaceutical industry. The present invention provides new means and methods for the determination of biopharmaceutical HOS and associated conformation using improved devices and methodologies for flash photo-oxidation of proteins to determine their higher order biomolecular structure, and such is responsive to the increased demand for new and improved HOS analytical means in the biopharmaceutical industry.
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公开(公告)号：US10816468B2
公开(公告)日：2020-10-27
申请号：US16316006
申请日：2018-05-25
Applicant: GenNext Technologies, Inc.
Inventor： Scot Randy Weinberger , Ronald Carl Orlando , Joshua Shane Sharp , Robert Wallace Egan , Jeffrey Jonathan Persoff
Abstract: Flash Photo-Oxidation Device and Higher Order Structural Analysis is employed for higher order structural analysis of biomolecules. Biomolecular higher order structure (HOS) results from the confounded superimposition of a biomolecule's secondary, tertiary, and quaternary structure and defines the manner in which a biomolecule presents itself and interacts with other biomolecules in living systems. A rapidly growing class of therapeutic drugs, known as biotherapeutics, comprises a variety of proteins, whose therapeutic properties are inherently linked and dependent upon their HOS. As such, HOS analysis of biotherapeutics is an important analytical requirement in the biopharmaceutical industry. The present invention provides new means and methods for the determination of biopharmaceutical HOS and associated conformation using improved devices and methodologies for flash photo-oxidation of proteins to determine their higher order biomolecular structure, and such is responsive to the increased demand for new and improved HOS analytical means in the biopharmaceutical industry.
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公开(公告)号：US20230296615A1
公开(公告)日：2023-09-21
申请号：US18142538
申请日：2023-05-02
Applicant: GenNext Technologies, Inc.
Inventor： Scot Randy Weinberger , Ronald Carl Orlando , Joshua Shane Sharp , Robert Wallace Egan , Jeffrey Jonathan Persoff
CPC classification number: G01N33/6803 , G01N21/59 , G01N21/6428 , H01J49/0036 , G01N21/631 , G01N2021/6439
Abstract: Flash Photo-Oxidation Device and Higher Order Structural Analysis is employed for higher order structural analysis of biomolecules. Biomolecular higher order structure (HOS) results from the confounded superimposition of a biomolecule's secondary, tertiary, and quaternary structure and defines the manner in which a biomolecule presents itself and interacts with other biomolecules in living systems. A rapidly growing class of therapeutic drugs, known as biotherapeutics, comprises a variety of proteins, whose therapeutic properties are inherently linked and dependent upon their HOS. As such, HOS analysis of biotherapeutics is an important analytical requirement in the biopharmaceutical industry. The present invention provides new means and methods for the determination of biopharmaceutical HOS and associated conformation using improved devices and methodologies for flash photo-oxidation of proteins to determine their higher order biomolecular structure, and such is responsive to the increased demand for new and improved HOS analytical means in the biopharmaceutical industry.
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公开(公告)号：US20210156869A1
公开(公告)日：2021-05-27
申请号：US17168472
申请日：2021-02-05
Applicant: GenNext Technologies, Inc.
Inventor： Scot Randy Weinberger , Ronald Carl Orlando , Joshua Shane Sharp , Robert Wallace Egan , Jeffrey Jonathan Persoff
Abstract: Flash Photo-Oxidation Device and Higher Order Structural Analysis is employed for higher order structural analysis of biomolecules. Biomolecular higher order structure (HOS) results from the confounded superimposition of a biomolecule's secondary, tertiary, and quaternary structure and defines the manner in which a biomolecule presents itself and interacts with other biomolecules in living systems. A rapidly growing class of therapeutic drugs, known as biotherapeutics, comprises a variety of proteins, whose therapeutic properties are inherently linked and dependent upon their HOS. As such, HOS analysis of biotherapeutics is an important analytical requirement in the biopharmaceutical industry. The present invention provides new means and methods for the determination of biopharmaceutical HOS and associated conformation using improved devices and methodologies for flash photo-oxidation of proteins to determine their higher order biomolecular structure, and such is responsive to the increased demand for new and improved HOS analytical means in the biopharmaceutical industry.
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