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公开(公告)号：US20150044253A1
公开(公告)日：2015-02-12
申请号：US14525883
申请日：2014-10-28
Applicant: GLAXOSMITHKLINE BIOLOGICALS S.A.
Inventor： Ralph Leon BIEMANS , Dominique BOUTRIAU , Carine CAPIAU , Philippe DENOEL , Pierre DUVIVIER , Jan POOLMAN
IPC: A61K39/102 , A61K39/29 , A61K39/00 , A61K39/05 , A61K39/08 , A61K39/095 , A61K39/02
CPC classification number: A61K39/385 , A61K39/0017 , A61K39/0018 , A61K39/05 , A61K39/08 , A61K39/092 , A61K39/095 , A61K39/099 , A61K39/102 , A61K39/116 , A61K39/12 , A61K39/145 , A61K39/292 , A61K2039/545 , A61K2039/55 , A61K2039/575 , A61K2039/6037 , A61K2039/62 , A61K2039/627 , A61K2039/70 , C07H3/00 , C12N7/00 , C12N2730/10134 , C12N2760/16234 , C12N2760/16271 , C12N2770/32634 , Y02A50/466 , Y02A50/472 , Y02A50/484
Abstract: The present application discloses an immunogenic composition comprising a Hib saccharide conjugate, at least one additional bacterial, for example N. meningitidis, saccharide conjugate(s), and a further antigen selected from the group consisting of whole cell pertussis and hepatitis B surface antigen, wherein the saccharide dose of the Hib saccharide conjugate is less than 5 μg.
Abstract translation: 本申请公开了一种免疫原性组合物，其包含Hib糖结合物，至少一种额外的细菌，例如脑膜炎奈瑟球菌，糖结合物和选自全细胞百日咳和乙型肝炎表面抗原的另外的抗原， 其中Hib糖共轭物的糖剂量小于5μg。
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公开(公告)号：US20150079129A1
公开(公告)日：2015-03-19
申请号：US14550185
申请日：2014-11-21
Applicant: Glaxosmithkline Biologicals S.A.
Inventor： Carine CAPIAU , Marguerite DESCHAMPS , Pierre Michel DESMONS , Craig Antony Joseph LAFERRIERE , Jan POOLMAN , Jean-Paul PRIEELS
CPC classification number: A61K39/095 , A61K39/07 , A61K39/092 , A61K39/39 , A61K47/646 , A61K2039/505 , A61K2039/55505 , A61K2039/55516 , A61K2039/55544 , A61K2039/55572 , A61K2039/55583 , A61K2039/57 , A61K2039/6068 , A61K2039/70 , C07K16/1275 , Y02A50/484
Abstract: The present invention relates to the field of bacterial polysaccharide antigen vaccines. In particular, the present invention relates to bacterial polysaccharides conjugated to protein D from H. influenzae.
Abstract translation: 本发明涉及细菌多糖抗原疫苗领域。 特别地，本发明涉及与流感嗜血杆菌的蛋白D结合的细菌多糖。
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公开(公告)号：US20150079125A1
公开(公告)日：2015-03-19
申请号：US14550345
申请日：2014-11-21
Applicant: GLAXOSMITHKLINE BIOLOGICALS S.A.
Inventor： Carine CAPIAU , Marguerite DESCHAMPS , Pierre Michel DESMONS , Craig Antony Joseph LAFERRIERE , Jan POOLMAN , Jean-Paul PRIEELS
IPC: A61K47/48 , A61K39/095 , A61K39/102
CPC classification number: A61K47/4833 , A61K39/092 , A61K39/095 , A61K39/102 , A61K39/12 , A61K39/155 , A61K47/646 , A61K2039/55505 , A61K2039/55572 , A61K2039/6037 , A61K2039/6068 , A61K2039/6075 , A61K2039/70 , Y02A50/414 , Y02A50/484 , Y10S424/831
Abstract: The present invention relates to the field of bacterial polysaccharide antigen vaccines. In particular, the present invention relates to bacterial polysaccharides conjugated to protein D from H. influenzae.
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