公开(公告)号：US20240142444A1

公开(公告)日：2024-05-02

申请号：US17622403

申请日：2020-06-25

Applicant: GEORGE MASON UNIVERSITY

Inventor： Lance LIOTTA ,  Marissa A. HOWARD ,  Alessandra Luchini KUNKEL ,  Sameen YUSUF ,  Sara SHARIF ,  Ruben MAGNI

IPC: G01N33/543 ,  G01N33/569

CPC classification number: G01N33/54346 ,  G01N33/56905 ,  G01N33/56911 ,  G01N33/5695 ,  G01N2333/20 ,  G01N2333/35

Abstract: The invention relates to a relates to a highly sensitive, non-invasive diagnostic method for detection infectious diseases. In one embodiment, the invention relates to novel rapid, self-working, visual field test for a panel of disease specific derived biomarkers. In one embodiment, the invention comprises a collecting device comprising a collapsible non hygroscopic net tethered with immobilized nanoparticles to capture and concentrate a target analyte present in a fluid; wherein the nanoparticle comprises a core and a shell, wherein the core comprises a molecular bait. The invention also relates to identification of biomarkers for identification of various pathogenic diseases.