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公开(公告)号：US09613254B1
公开(公告)日：2017-04-04
申请号：US14871667
申请日：2015-09-30
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Brion Daryl Sarachan , John Frederick Graf , Vidya Pundalik Kamath
CPC classification number: G06K9/00147 , G06K9/00134 , G06K9/0014 , G06K9/3241 , G06K9/6215 , G06K9/6219 , G06K9/6224 , G06K9/6247
Abstract: The present disclosure relates to characterization of biological samples. By way of example, a biological sample may be contacted with a plurality of probes specific for targets in the sample, such as probes for immune markers and segmenting probes. Acquired image data of the sample may be used to segment the images into epithelial and stromal regions to characterize individual cells in the sample based on the binding of the probes. Further, the biological sample may be characterized by a heterogeneity of the characterized cells.
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Patent Agency Ranking
公开(公告)号：US09607375B2
公开(公告)日：2017-03-28
申请号：US14729982
申请日：2015-06-03
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Brion Daryl Sarachan , John Frederick Graf , Anup Sood , Vidya Pundalik Kamath
CPC classification number: G06F17/30259 , G06F19/00 , G06F19/321
Abstract: Dynamic linking of pathway maps and cell maps is disclosed in certain embodiments. In such embodiments, the pathway maps are linked to spatially-localized regional nucleic acid data (e.g., sequence data), as opposed to non-spatially selected nucleic acid data. The pathway map and cell map data may be linked so that interactions results in changes or updates to the linked map, such as the selection or highlighting of cells exhibiting pathway map characteristics specified by a user of updating of node values or states to correspond to that of a cell or cells selected by the user.
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公开(公告)号：US20150087982A1
公开(公告)日：2015-03-26
申请号：US14033452
申请日：2013-09-21
Applicant: General Electric Company
Inventor： Rakesh Mullick , Pavan Kumar Veerabhadra Annangi , Xiaoxing Li , Vidya Pundalik Kamath , Fei Zhao , Vivek Prabhakar Vaidya , Soma Biswas
CPC classification number: A61B8/5223 , A61B8/085 , G06T7/0012 , G06T7/41 , G06T2207/10132 , G06T2207/20076 , G06T2207/30068 , G06T2207/30096
Abstract: A method is provided for detecting lesions in ultrasound images. The method includes acquiring ultrasound information, determining discriminative descriptors that describe the texture of a candidate lesion region, and classifying each of the discriminative descriptors as one of a top boundary pixel, a lesion interior pixel, a lower boundary pixel, or a normal tissue pixel. The method also includes determining a pattern of transitions between the classified discriminative descriptors, and classifying the candidate lesion region as a lesion or normal tissue based on the pattern of transitions between the classified discriminative descriptors.
Abstract translation: 提供了一种用于检测超声图像中的损伤的方法。 该方法包括获取超声信息，确定描述候选病变区域的纹理的区分描述符，并将每个鉴别描述符分类为顶边界像素，病变内部像素，下边界像素或正常组织像素之一 。 该方法还包括确定分类的辨别描述符之间的转换模式，并且基于分类的识别描述符之间的转换模式将候选病变区域划分为病变或正常组织。
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公开(公告)号：US10238368B2
公开(公告)日：2019-03-26
申请号：US14033452
申请日：2013-09-21
Applicant: General Electric Company
Inventor： Rakesh Mullick , Pavan Kumar Veerabhadra Annangi , Xiaoxing Li , Vidya Pundalik Kamath , Fei Zhao , Vivek Prabhakar Vaidya , Soma Biswas
Abstract: A method is provided for detecting lesions in ultrasound images. The method includes acquiring ultrasound information, determining discriminative descriptors that describe the texture of a candidate lesion region, and classifying each of the discriminative descriptors as one of a top boundary pixel, a lesion interior pixel, a lower boundary pixel, or a normal tissue pixel. The method also includes determining a pattern of transitions between the classified discriminative descriptors, and classifying the candidate lesion region as a lesion or normal tissue based on the pattern of transitions between the classified discriminative descriptors.
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公开(公告)号：US20170091527A1
公开(公告)日：2017-03-30
申请号：US14871667
申请日：2015-09-30
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Brion Daryl Sarachan , John Frederick Graf , Vidya Pundalik Kamath
CPC classification number: G06K9/00147 , G06K9/00134 , G06K9/0014 , G06K9/3241 , G06K9/6215 , G06K9/6219 , G06K9/6224 , G06K9/6247
Abstract: The present disclosure relates to characterization of biological samples. By way of example, a biological sample may be contacted with a plurality of probes specific for targets in the sample, such as probes for immune markers and segmenting probes. Acquired image data of the sample may be used to segment the images into epithelial and stromal regions to characterize individual cells in the sample based on the binding of the probes. Further, the biological sample may be characterized by a heterogeneity of the characterized cells.
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公开(公告)号：US20160358326A1
公开(公告)日：2016-12-08
申请号：US14729982
申请日：2015-06-03
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Brion Daryl Sarachan , John Frederick Graf , Anup Sood , Vidya Pundalik Kamath
CPC classification number: G06F17/30259 , G06F19/00 , G06F19/321
Abstract: Dynamic linking of pathway maps and cell maps is disclosed in certain embodiments. In such embodiments, the pathway maps are linked to spatially-localized regional nucleic acid data (e.g., sequence data), as opposed to non-spatially selected nucleic acid data. The pathway map and cell map data may be linked so that interactions results in changes or updates to the linked map, such as the selection or highlighting of cells exhibiting pathway map characteristics specified by a user of updating of node values or states to correspond to that of a cell or cells selected by the user.
Abstract translation: 在某些实施方案中公开了途径图和细胞图的动态连接。 在这样的实施方案中，与非空间选择的核酸数据相反，途径图连接到空间定位的区域核酸数据（例如序列数据）。 路径图和细胞图谱数据可以被链接，使得交互导致对链接的图的改变或更新，诸如显示由用户更新节点值或状态所指示的路径图特征的细胞的选择或突出显示，以对应于该 的用户选择的单元格或单元格。
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