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公开(公告)号：US09829474B2
公开(公告)日：2017-11-28
申请号：US14884992
申请日：2015-10-16
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Rui Chen , Andrew Michael Leach , Manuel Alfred Palacios
CPC classification number: G01N33/15 , C07F15/025 , G01N21/31
Abstract: The present invention is directed to methods of acetate quantification and acetate complexes useful in the methods of acetate quantification. Such methods and complexes are useful for any application where acetate quantification is desired, including measuring of concentration of 13C hyperpolarized acetate for imaging agent quality control in MRI and NMR spectroscopy. The disclosed acetate complexes may be prepared from acetate, Fe3+, and sulfosalicylic acid and from acetate, Fe3+, and salicylic acid.
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Patent Agency Ranking
公开(公告)号：US20150332829A1
公开(公告)日：2015-11-19
申请号：US14281105
申请日：2014-05-19
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Ernst Wolfgang Stautner , Andrew Michael Leach
CPC classification number: F25D3/10 , F17C3/085 , F17C2203/0687 , F25B9/10 , F25B25/005 , F25B2400/17 , F25D19/00 , G01R33/3815 , H01F6/04
Abstract: A cryogen cooling system to cool a superconducting magnet is disclosed herein utilizing embedded vertical tubing with a large heat exchanging surface area. The tubing encompasses the magnet which is further surrounded by a 4 Kelvin thermal shield for extended ride-through. In one embodiment, the system is a hyperpolarizer having an internal high-pressure gas storage for quench gas and to initiate cool-down. Aspects of the invention utilize a minimal volume of pressurized gas, for example, four (4) liters of pressurized gaseous helium in a 150 mL liquid helium system. As such, the prior vent stack has been removed, along with the helium vessel and quench paths/ducts. The method of using the system is further simplified during ramping while the cool-down process utilizing liquids supplied from external dewars has been eliminated. Significant advantages include reducing the helium volume (and cost associated therewith) and allowing for a hermetically sealed vacuum system that is leak-proof.
Abstract translation: 本文公开了一种用于冷却超导磁体的冷冻剂冷却系统，其利用具有大的热交换表面积的嵌入式垂直管。 管道包围磁体，进一步被四开尔文防护罩包围，以延长穿越。 在一个实施例中，该系统是具有用于骤冷气体的内部高压气体存储并启动冷却的超极化器。 本发明的方面在150mL液氦系统中使用最小体积的加压气体，例如四（4）升加压气态氦。 因此，先前的排气堆已经与氦气容器和淬火路径/管道一起被去除。 使用该系统的方法在斜坡期间进一步简化，而利用从外部杜瓦瓶提供的液体的冷却过程已被消除。 显着的优点包括降低氦体积（和与之相关的成本），并允许密封的真空系统是防漏的。
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公开(公告)号：US10591557B2
公开(公告)日：2020-03-17
申请号：US13662595
申请日：2012-10-29
Applicant: General Electric Company
Inventor： Andrew Michael Leach , James Richard Trigger , John Arthur Urbahn
Abstract: Provided is an apparatus and method comprising, an airlock chamber; a cryogenic chamber; an equilibrator positioned between the airlock chamber and the cryogenic chamber that is configured to allow for the passage of a sample along to the cryogenic chamber; and a cooling unit that is thermally coupled to the equilibrator. Collectively, the airlock chamber, equilibrator, and the cryogenic chamber define a travel path. A machine-readable medium, comprising instructions which when executed by a controller causes a sample to be cooled, is also provided.
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4.发明申请公开(公告)号：US20130047633A1
公开(公告)日：2013-02-28
申请号：US13662595
申请日：2012-10-29
Applicant: General Electric Company
Inventor： Andrew Michael Leach , James Richard Trigger , John Arthur Urbahn
Abstract: Provided is an apparatus and method comprising, an airlock chamber; a cryogenic chamber; an equilibrator positioned between the airlock chamber and the cryogenic chamber that is configured to allow for the passage of a sample along to the cryogenic chamber; and a cooling unit that is thermally coupled to the equilibrator. Collectively, the airlock chamber, equilibrator, and the cryogenic chamber define a travel path. A machine-readable medium, comprising instructions which when executed by a controller causes a sample to be cooled, is also provided.
Abstract translation: 提供一种装置和方法，包括：气闸室; 低温室; 位于所述气闸室和所述低温室之间的平衡器，所述平衡器被构造成允许样品通过所述低温室; 以及与所述平衡器热耦合的冷却单元。 总的来说，气闸室，平衡器和低温室限定行进路径。 一种机器可读介质，包括当由控制器执行时使指示被冷却的指令。
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公开(公告)号：US10184711B2
公开(公告)日：2019-01-22
申请号：US14281105
申请日：2014-05-19
Applicant: GENERAL ELECTRIC COMPANY
Inventor： Ernst Wolfgang Stautner , Andrew Michael Leach
Abstract: A cryogen cooling system to cool a superconducting magnet is disclosed herein utilizing embedded vertical tubing with a large heat exchanging surface area. The tubing encompasses the magnet which is further surrounded by a 4 Kelvin thermal shield for extended ride-through. In one embodiment, the system is a hyperpolarizer having an internal high-pressure gas storage for quench gas and to initiate cool-down. Aspects of the invention utilize a minimal volume of pressurized gas, for example, four (4) liters of pressurized gaseous helium in a 150 mL liquid helium system. As such, the prior vent stack has been removed, along with the helium vessel and quench paths/ducts. The method of using the system is further simplified during ramping while the cool-down process utilizing liquids supplied from external dewars has been eliminated. Significant advantages include reducing the helium volume (and cost associated therewith) and allowing for a hermetically sealed vacuum system that is leak-proof.
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公开(公告)号：US20150168079A1
公开(公告)日：2015-06-18
申请号：US14108387
申请日：2013-12-17
Applicant: General Electric Company
Inventor： Ernst Wolfgang Stautner , Andrew Michael Leach
IPC: F28D15/06
CPC classification number: F28D15/06 , F25B9/14 , F25D19/006 , F28D15/0266 , F28D15/0275 , F28D15/043 , F28F2013/005
Abstract: A thermal switching device is presented. The thermal switching device includes a plurality of serpentine capillaries having a first end and a second end, where the first end is configured to be operatively coupled to a heating unit and the second end is configured to be operatively coupled to a cooling unit, and where the plurality of serpentine capillaries is configured to transfer heat from the heating unit to the cooling unit by circulating a working fluid in the plurality of serpentine capillaries.
Abstract translation: 介绍了一种热交换装置。 热开关装置包括多个具有第一端和第二端的蛇形毛细管，其中第一端被配置为可操作地耦合到加热单元，并且第二端构造成可操作地联接到冷却单元，并且其中 多个蛇形毛细管被构造成通过循环多个蛇形毛细管中的工作流体将热量从加热单元传递到冷却单元。
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