公开(公告)号：US09829474B2

公开(公告)日：2017-11-28

申请号：US14884992

申请日：2015-10-16

Applicant: GENERAL ELECTRIC COMPANY

Inventor： Rui Chen ,  Andrew Michael Leach ,  Manuel Alfred Palacios

IPC: G01N33/00 ,  G01N33/15 ,  C07F15/02 ,  G01N21/31

CPC classification number: G01N33/15 ,  C07F15/025 ,  G01N21/31

Abstract: The present invention is directed to methods of acetate quantification and acetate complexes useful in the methods of acetate quantification. Such methods and complexes are useful for any application where acetate quantification is desired, including measuring of concentration of 13C hyperpolarized acetate for imaging agent quality control in MRI and NMR spectroscopy. The disclosed acetate complexes may be prepared from acetate, Fe3+, and sulfosalicylic acid and from acetate, Fe3+, and salicylic acid.