-
公开(公告)号：US09995755B2
公开(公告)日：2018-06-12
申请号：US14021947
申请日：2013-09-09
Applicant: Genentech, Inc.
Inventor： Joseph R. Arron , Richard W. Erickson , Michelle Freemer , Meredith Hazen , Guiquan Jia , John G. Matthews , Wendy Putnam , Heleen Scheerens , Yanan Zheng
IPC: A61K39/00 , A61K45/00 , G01N33/68 , C07K16/28 , A61K39/395 , C07K16/18 , A61K31/522 , A61K31/573 , A61K45/06
CPC classification number: G01N33/6884 , A61K31/522 , A61K31/573 , A61K39/3955 , A61K39/39566 , A61K45/06 , C07K16/18 , C07K16/28 , G01N33/6887 , G01N33/6893 , G01N2333/475 , G01N2800/122 , G01N2800/52
Abstract: Methods of diagnosing and treating disorders related to TH2 inhibition, including but not limited to asthma, are provided. Also provided are methods of selecting or identifying patients for treatment with certain therapeutic agents that are TH2 pathway inhibitors.
-
公开(公告)号：US10047158B2
公开(公告)日：2018-08-14
申请号：US15895741
申请日：2018-02-13
Applicant: Genentech, Inc.
Inventor： Jane L. Grogan , Robert J. Johnston , Yan Wu , Wei-Ching Liang , Patrick Lupardus , Mahesh Yadav , Dhaya Seshasayee , Meredith Hazen
CPC classification number: C07K16/28 , A61K38/177 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/2818 , C07K16/2827 , C07K16/2878 , C07K16/3061 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/567 , C07K2317/70 , C07K2317/75 , C07K2317/76 , C07K2317/90 , C07K2317/92 , C07K2317/94 , Y02A50/466
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
-
公开(公告)号：US11725050B2
公开(公告)日：2023-08-15
申请号：US16903300
申请日：2020-06-16
Applicant: Genentech, Inc.
Inventor： Philip E. Hass , Meredith Hazen , Yi-Chun Hsiao , Rajita Khosla , Gerald R. Nakamura , Dhaya Seshasayee , Menno Van Lookeren Campagne , Hongkang Xi , Wenwu Zhai , Jack Bevers, III , Nancy Chiang
CPC classification number: C07K16/244 , A61K39/3955 , C07K16/22 , C07K16/40 , C12N15/63 , A61K2039/507 , C07K2317/14 , C07K2317/24 , C07K2317/31 , C07K2317/41 , C07K2317/53 , C07K2317/54 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92
Abstract: The invention provides interleukin-33 (IL-33) antibodies and methods of using the same.
-
公开(公告)号：US10093730B2
公开(公告)日：2018-10-09
申请号：US14937778
申请日：2015-11-10
Applicant: Genentech, Inc.
Inventor： Philip E. Hass , Meredith Hazen , Yi-Chun Hsiao , Rajita Khosla , Gerald R. Nakamura , Dhaya Seshasayee , Menno Van Lookeren Campagne , Hongkang Xi , Wenwu Zhai , Jack Bevers, III , Nancy Chiang
Abstract: The invention provides interleukin-33 (IL-33) antibodies and methods of using the same.
-
公开(公告)号：US11226341B2
公开(公告)日：2022-01-18
申请号：US15992115
申请日：2018-05-29
Applicant: GENENTECH, INC.
Inventor： Joseph R. Arron , Richard W. Erickson , Michelle Freemer , Meredith Hazen , Guiquan Jia , John G. Matthews , Wendy Putnam , Heleen Scheerens , Yanan Zheng
IPC: A61K39/395 , G01N33/68 , C07K16/28 , C07K16/24 , C07K16/18 , A61K31/522 , A61K31/573 , A61K45/06
Abstract: Methods of diagnosing and treating disorders related to TH2 inhibition, including but not limited to asthma, are provided. Also provided are methods of selecting or identifying patients for treatment with certain therapeutic agents that are TH2 pathway inhibitors.
-
Patent Agency Ranking
公开(公告)号：US10723795B2
公开(公告)日：2020-07-28
申请号：US16119667
申请日：2018-08-31
Applicant: Genentech, Inc.
Inventor： Philip E. Hass , Meredith Hazen , Yi-Chun Hsiao , Rajita Khosla , Gerald R. Nakamura , Dhaya Seshasayee , Menno Van Lookeren Campagne , Hongkang Xi , Wenwu Zhai , Jack Bevers, III , Nancy Chiang
Abstract: The invention provides interleukin-33 (IL-33) antibodies and methods of using the same.
-
公开(公告)号：US10017572B2
公开(公告)日：2018-07-10
申请号：US15274603
申请日：2016-09-23
Applicant: Genentech, Inc.
Inventor： Jane L. Grogan , Robert J. Johnston , Yan Wu , Wei-Ching Liang , Patrick Lupardus , Mahesh Yadav , Dhaya Seshasayee , Meredith Hazen
CPC classification number: C07K16/28 , A61K38/177 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/2818 , C07K16/2827 , C07K16/2878 , C07K16/3061 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/567 , C07K2317/70 , C07K2317/75 , C07K2317/76 , C07K2317/90 , C07K2317/92 , C07K2317/94 , Y02A50/466
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
-
公开(公告)号：US09684000B2
公开(公告)日：2017-06-20
申请号：US14021698
申请日：2013-09-09
Applicant: Genentech, Inc.
Inventor： Joseph R. Arron , Richard W. Erickson , Michelle Freemer , Meredith Hazen , Guiquan Jia , John G. Matthews , Wendy Putnam , Heleen Scheerens , Yanan Zheng
IPC: C07K16/00 , G01N33/68 , C07K16/28 , A61K39/395 , C07K16/18 , A61K31/522 , A61K31/573 , A61K45/06
CPC classification number: G01N33/6884 , A61K31/522 , A61K31/573 , A61K39/3955 , A61K39/39566 , A61K45/06 , C07K16/18 , C07K16/28 , G01N33/6887 , G01N33/6893 , G01N2333/475 , G01N2800/122 , G01N2800/52
Abstract: Methods of diagnosing and treating disorders related to TH2 inhibition, including but not limited to asthma, are provided. Also provided are methods of selecting or identifying patients for treatment with certain therapeutic agents that are TH2 pathway inhibitors.
-
公开(公告)号：US09580514B2
公开(公告)日：2017-02-28
申请号：US14400684
申请日：2013-03-14
Applicant: Genentech, Inc.
Inventor： Sunil Bhakta , Meredith Hazen , Jo-Anne S Hongo , Jagath R Junutula , Isidro Hotzel , Yonglei Shang , Shang-Fan Yu
IPC: A61K39/395 , C07K16/30 , A61K47/48 , A61K51/10 , C12Q1/68 , G01N33/574 , A61K39/00
CPC classification number: C07K16/30 , A61K47/6803 , A61K47/6809 , A61K47/6817 , A61K47/6855 , A61K51/1051 , A61K2039/505 , A61K2039/6037 , C07K2317/24 , C07K2317/76 , C07K2317/77 , C12Q1/6886 , C12Q2600/158 , C12Q2600/16 , G01N33/57415 , G01N33/57423 , G01N2333/47 , G01N2500/02
Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same. In certain aspects, the isolated nucleic acid molecule comprises a nucleotide sequence having at least about 80% nucleic acid sequence identity, alternatively at least about 81%, 82%, 83%, 84%, 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, 99% or 100% nucleic acid sequence identity, to (a) a DNA molecule encoding a full-length TAT polypeptide having an amino acid sequence as disclosed herein, a TAT polypeptide amino acid sequence lacking the signal peptide as disclosed herein, an extracellular domain of a transmembrane TAT polypeptide, with or without the signal peptide, as disclosed herein.
Abstract translation: 本发明涉及用于哺乳动物肿瘤诊断和治疗的物质组合物，以及使用这些物质组合物的方法。 在某些方面，分离的核酸分子包含具有至少约80％核酸序列同一性，或至少约81％，82％，83％，84％，85％，86％，87％，88 ％，89％，90％，91％，92％，93％，94％，95％，96％，97％，98％，99％或100％的核酸序列同一性。 如本文公开的具有本文公开的氨基酸序列的全长TAT多肽，缺乏本文公开的信号肽的TAT多肽氨基酸序列，跨膜TAT多肽的胞外结构域，具有或不具有信号肽。
-
公开(公告)号：US20140044645A1
公开(公告)日：2014-02-13
申请号：US14021698
申请日：2013-09-09
Applicant: Genentech, Inc.
Inventor： Joseph R. Arron , Richard W. Erickson , Michelle Freemer , Meredith Hazen , Guiquan Jia , John G. Matthews , Wendy Putnam , Heleen Scheerens , Yanan Zheng
IPC: G01N33/68 , A61K39/395 , C07K16/18
CPC classification number: G01N33/6884 , A61K31/522 , A61K31/573 , A61K39/3955 , A61K39/39566 , A61K45/06 , C07K16/18 , C07K16/28 , G01N33/6887 , G01N33/6893 , G01N2333/475 , G01N2800/122 , G01N2800/52
Abstract: Methods of diagnosing and treating disorders related to TH2 inhibition, including but not limited to asthma, are provided. Also provided are methods of selecting or identifying patients for treatment with certain therapeutic agents that are TH2 pathway inhibitors.
-
-
-
-
-
-
-
-
-
Search Results
14
records
(took 0.036 seconds)
