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公开(公告)号:US20160024217A1
公开(公告)日:2016-01-28
申请号:US14670079
申请日:2015-03-26
申请人: GENENTECH, INC.
IPC分类号: C07K16/28 , C07K16/22 , C07K14/705 , C12N5/00
CPC分类号: C07K16/2878 , C07K14/70575 , C07K16/18 , C07K16/22 , C07K2317/14 , C07K2319/30 , C12N5/0018 , C12N5/0043 , C12N2500/32 , C12N2500/33 , C12N2500/90
摘要: The present invention relates generally to glutamine-free cell culture media supplemented with asparagine. The invention further concerns the production of recombinant proteins, such as antibodies, in asparagine-supplemented glutamine-free mammalian cell culture.
摘要翻译: 本发明一般涉及补充天冬酰胺的不含谷氨酰胺的细胞培养基。 本发明还涉及在天冬酰胺补充的不含谷氨酰胺的哺乳动物细胞培养物中重组蛋白质如抗体的产生。