公开(公告)号：US20210316054A1

公开(公告)日：2021-10-14

申请号：US17357295

申请日：2021-06-24

申请人： GAMBRO LUNDIA AB

发明人： Sture Hobro ,  Jonas Fors ,  Olof Jansson

IPC分类号： A61M1/16

摘要： A renal failure therapy system includes a dialysis fluid circuit including a dialysis fluid pump; a source of physiological cleaning, disinfecting, and/or decalcifying substance in fluid communication with the dialysis fluid circuit; a source of purified water in fluid communication with the dialysis fluid circuit; and a logic implementer in operable communication with the dialysis fluid pump, the logic implementer causing the physiological cleaning, disinfecting, and/or decalcifying substance from its source to be added to purified water from the purified water source to form a mixture and to circulate the mixture within the dialysis fluid circuit using the dialysis fluid pump to at least one of clean, disinfect or decalcify at least a portion of the dialysis fluid circuit without a subsequent rinse.

公开(公告)号：US10894119B2

公开(公告)日：2021-01-19

申请号：US16095088

申请日：2017-05-05

申请人： GAMBRO LUNDIA AB

发明人： Anders Wieslander ,  Olof Jansson ,  Ola Carlsson ,  Sture Hobro ,  Karin Sandin ,  Simon Enarsson

IPC分类号： A61K9/00 ,  A61M1/28 ,  A61M1/16 ,  A61K31/19 ,  A61K31/194 ,  A61K31/7004 ,  A61K33/14 ,  A61K33/20

摘要： The present invention concerns a system for preparing a ready-to-use peritoneal dialysis fluid. The system comprises a) a proportioning device; b) at least one source of water; c) at least one source of first concentrate adapted for connection with a) and b), d) at least one source of second concentrate adapted for connection with a) and b), and optionally, e) at least one source of further concentrate adapted for connection with a) and b), wherein the first concentrate comprises glucose and has a pH of between 1.5 and 4, and wherein the second concentrate comprises a physiologically acceptable buffer and has a pH of between 5.5 and 9.0.

公开(公告)号：US09623165B2

公开(公告)日：2017-04-18

申请号：US14650210

申请日：2013-12-09

申请人： GAMBRO LUNDIA AB

发明人： Olof Jansson ,  Sture Hobro ,  Lennart Jonsson ,  Anton Persson

IPC分类号： A61M37/00 ,  A61M1/16 ,  F17D1/14 ,  A61M1/14

CPC分类号： A61M1/1601 ,  A61M1/14 ,  A61M1/165 ,  A61M2205/121 ,  A61M2205/128 ,  A61M2205/3334 ,  A61M2205/3375 ,  A61M2205/3389 ,  A61M2205/70 ,  F17D1/14

摘要： A cassette is provided for installation in a dialysis monitor to pump a treatment solution through a dialyzer. The cassette is a unitary component with a hydraulic manifold (53) and a pneumatic manifold (54) integrated into a body (52). The body (52) has connectors for connecting the hydraulic manifold (53) to the dialyzer and the pneumatic manifold (54) to a pneumatic pressure source. A set of solution pumps is integrated in the cassette, and each solution pump includes a pump cavity inside the body. The solution pumps are operable to displace the treatment solution through the hydraulic manifold (53) to and/or from the dialyzer by action of a reciprocating gas-liquid interface in the pump cavity (30) of the respective solution pump. The gas-liquid interface is formed directly between a gaseous substance and the treatment solution. A valve arrangement (58) is attached to the body (52) and operable to control admission of the gaseous substance and the treatment solution to the pump cavity (30) so as to reciprocate the gas-liquid interface and thereby pump the treatment solution through the hydraulic manifold (53). The cassette is configured to pump the treatment solution without moving parts inside the body (52).

公开(公告)号：US20160310657A1

公开(公告)日：2016-10-27

申请号：US15104861

申请日：2014-12-09

申请人： GAMBRO LUNDIA AB

发明人： Kristian Solem ,  David Stefani ,  Sture Hobro ,  Bo Olde

IPC分类号： A61M1/36 ,  G01F23/14

CPC分类号： A61M1/3627 ,  A61M1/3624 ,  A61M1/3626 ,  A61M1/367 ,  A61M2205/123 ,  A61M2205/3331 ,  A61M2205/3386 ,  A61M2205/3389 ,  G01F23/14 ,  G01F23/18

摘要： An apparatus (1) is described for extracorporeal blood treatment, comprising a treatment unit (2), an extracorporeal blood circuit (8) and a fluid evacuation line (10). A venous chamber (12) is placed in a blood return line (7) and is arranged in use to contain a gas in an upper portion (120) and blood at a predetermined level in a lower portion. The apparatus (1) comprises a control unit (21) connected to a first pressure sensor (14) and configured to: receive from the first pressure sensor (14) a first signal (P1(t)) relating to a time variable pressure (P(t)) of the blood flow; calculate a phase shift (θ) between the first signal (P1(t)) and a reference signal (P2(t)) correlated to the time variable pressure (P(t)) detected at a location distinct from the upper portion (120) of the chamber (12); monitor the volume (V) of gas in the upper portion (120) of the chamber (12) through the phase shift (θ).

摘要翻译： 一种用于体外血液处理的装置（1），其包括处理单元（2），体外血液回路（8）和排液管线（10）。 静脉腔室（12）被放置在血液返回管线（7）中，并且在使用中被布置成在上部（120）中容纳气体，并在下部容纳预定水平的血液。 装置（1）包括连接到第一压力传感器（14）并被配置为：从第一压力传感器（14）接收与时间可变压力相关的第一信号（P1（t））的控制单元（21） P（t））; 计算第一信号（P1（t））和与在与上部不同的位置处检测到的时间可变压力（P（t））相关的参考信号（P2（t））之间的相移（θ） ）; 通过相移（θ）监测室（12）的上部（120）中的气体的体积（V）。

公开(公告)号：US20160279313A1

公开(公告)日：2016-09-29

申请号：US15034247

申请日：2014-11-11

申请人： GAMBRO LUNDIA AB

发明人： Sture Hobro

IPC分类号： A61M1/16 ,  A61L2/04

CPC分类号： A61M1/1662 ,  A61L2/04 ,  A61L2202/24 ,  A61M1/16 ,  A61M1/1601 ,  A61M1/166 ,  A61M1/1664 ,  A61M1/1686 ,  A61M2205/3317 ,  A61M2205/3324 ,  A61M2205/3368 ,  A61M2205/3393 ,  A61M2205/36 ,  A61M2205/50 ,  A61M2205/8206

摘要： A dialysis monitor with a treatment fluid path configured to provide treatment fluid to a dialyzer when dialysis treatment is performed by the dialysis monitor is provided. A battery unit is connected to a controller and at least a portion of the functional elements of the dialysis monitor in order to provide back-up power should the supply of external power be discontinued. Energy of the battery unit is used to provide energy to the heater in preparation for and/or at least partly during thermal disinfection of the treatment fluid path or when starting up the preparation of treatment fluid thereby shortening the time required for the thermal disinfection and the starting up of the preparation of treatment fluid, respectively.

摘要翻译： 本发明提供了一种具有处理流体路径的透析监测器，其被配置为在通过透析监测器进行透析治疗时向透析器提供治疗流体。 电池单元连接到控制器和透析监视器的功能元件的至少一部分，以便在停止供应外部电力时提供备用电力。 电池单元的能量用于向加热器提供能量以及/或至少部分地在处理流体路径的热消毒过程中或当启动处理流体的制备时，从而缩短热消毒所需的时间和 分别开始处理液的制备。

公开(公告)号：US11975130B2

公开(公告)日：2024-05-07

申请号：US16621629

申请日：2018-06-21

申请人： GAMBRO LUNDIA AB

发明人： Roger Nilsson ,  Björn Ericson ,  Jan Sternby ,  Thomas Hertz ,  Olof Jansson ,  Sture Hobro ,  Anders Wallenborg ,  Jonas Fors ,  Henrik Lindgren ,  Annmargret Håkansson

IPC分类号： A61M1/16 ,  A61M1/30 ,  A61M1/36

CPC分类号： A61M1/1609 ,  A61M1/304 ,  A61M1/367

摘要： A system and a method for renal replacement therapy includes a blood treatment unit connected to a blood circuit and a dialysis fluid circuit, the system further including a control unit configured to control the system according to control instructions during a treatment, so as to determine a system parameter value and an indication of membrane fouling of the membrane, and activate an automatic anti-fouling measure that includes a temporary change of the flow rate in the blood circuit and a temporary decrease of the ultrafiltration rate wherein a timing of the temporary change and a timing of the temporary reduction are synchronized.

公开(公告)号：US11260154B2

公开(公告)日：2022-03-01

申请号：US16754160

申请日：2017-10-11

申请人： GAMBRO LUNDIA AB

发明人： Helena Jeppsson ,  Jan Sternby ,  Thomas Hertz ,  Olof Jansson ,  Sture Hobro ,  Evi Martinson

IPC分类号： A61M1/16

摘要： Dialysis machines comprising a feed arrangement (170) to supply a dialysis fluid to a dialyzer (150) during dialysis treatment and a return arrangement (171) to remove the dialysis fluid from the dialyzer during dialysis treatment and forward it to an exit (129); a feed recirculation circuit (172) to allow a fluid of the feed arrangement to be re-circulated in a fluid loop path comprising, at least a portion of, the feed arrangement and the feed recirculation circuit and a return recirculation circuit (173) to allow a fluid of the return arrangement to re-circulate in an auxiliary fluid loop path comprising, at least a portion of, the return arrangement and the return recirculation circuit. A controller (160) configured to perform disinfection by re-circulating a disinfectant and/or a heated fluid through said fluid loop path and/or through said auxiliary fluid loop path. The dialysis machine (1) further comprises a feed forward arrangement (172) connected to the fluid loop path and arranged to enable a fluid of the feed arrangement (170) to be forwarded to the exit (129) by-passing the auxiliary fluid loop path.

公开(公告)号：US11135346B2

公开(公告)日：2021-10-05

申请号：US16124454

申请日：2018-09-07

申请人： GAMBRO LUNDIA AB

发明人： Sture Hobro ,  Olof Jansson ,  Jan Lunsjo

IPC分类号： A61M1/16 ,  A61L2/18 ,  A61L2/24 ,  A61M39/22

摘要： In an embodiment, a dialysis machine includes a dialyser, a fluid line in fluid communication with the dialyser, an inlet valve enabling fluid to flow into the fluid line towards the dialyser during a dialysis treatment, a disinfectant line connected to the fluid line via a disinfectant valve upstream of the dialyser, the disinfectant valve enabling a disinfectant fluid to be provided to at least part of the fluid line during a disinfection procedure, and a controller programmed to open the inlet valve, while the disinfectant line is connected to a source of disinfectant fluid, to create a positive pressure gradient across the disinfectant valve as fluid flows into the fluid line towards the dialyser, the positive pressure gradient ensuring that the disinfectant fluid from the source of disinfectant fluid does not leak into the fluid line during the dialysis treatment.

公开(公告)号：US11065374B2

公开(公告)日：2021-07-20

申请号：US16326095

申请日：2017-08-16

申请人： GAMBRO LUNDIA AB

发明人： Sture Hobro ,  Jonas Fors ,  Olof Jansson

IPC分类号： A61M1/16 ,  A61M1/36

摘要： A renal failure therapy system (10a, 10b) includes a dialysis fluid circuit (30) including a dialysis fluid pump (54, 58); a source (86, 90) of physiological cleaning, disinfecting, and/or decalcifying substance in fluid communication with the dialysis fluid circuit; a source (22) of purified water in fluid communication with the dialysis fluid circuit; and a logic implementer (20) in operable communication with the dialysis fluid pump (54,58), the logic implementer (20) causing the physiological cleaning, disinfecting, and/or decalcifying substance from its source (86, 90) to be added to purified water from the purified water source (22) to form a mixture and to circulate the mixture within the dialysis fluid circuit using the dialysis fluid pump (54,58) to at least one of clean, disinfect or decalcify at least a portion of the dialysis fluid circuit (30) without a subsequent rinse.

公开(公告)号：US10926018B2

公开(公告)日：2021-02-23

申请号：US15766185

申请日：2016-10-14

申请人： GAMBRO LUNDIA AB

发明人： Sture Hobro ,  Erik Torgny

IPC分类号： A61M1/34 ,  A61M1/16 ,  A61M1/36

摘要： A renal failure therapy system (10) includes a dialyzer (102); a blood circuit (100) in fluid communication with the dialyzer (102); a dialysis fluid circuit (30) in fluid communication with the dialyzer (102); a housing supporting the dialyzer (102), the blood circuit (100) and the dialysis fluid circuit (30); and at least one electrical socket (170) held by the housing, the electrical socket (170) providing a voltage output dedicated to a particular voltage type of external electrical device (200) for powering or charging the external electrical device (200), the at least one electrical socket (170) including electrical insulation for protecting a patient while powering the external electrical device (200).