公开(公告)号：US10545076B2

公开(公告)日：2020-01-28

申请号：US15515794

申请日：2014-10-20

Applicant: Foss Analytical A/S

Inventor： Claus Holm ,  Malin Dahl ,  Christer Zoffmann Bisgaard

IPC: G01N1/40 ,  B01D11/02 ,  G01N1/34 ,  G01N30/60 ,  G01N30/06

Abstract: Determination of Analytes in a Sample Matrix by Solvent Extraction A method for the assay of one or more analytes in a sample matrix comprising the steps of: performing analyte extraction on the sample matrix, said analyte extraction comprising combining the sample matrix with a solvent for an extraction period which is less than that required for reaching equilibrium; and separating the analyte containing solvent from the sample matrix; next measuring a level of analyte present in the separated solvent; and then applying in a computer a calibration by which is established a mathematical relationship between levels of analyte extracted from each of a plurality of reference samples by means of the process employed above in the extraction for the sample matrix and a reference value of the levels of analyte for each reference sample to thereby derive a measure of the level of analyte in the sample matrix. Specifically a method to determine the amount of mycotoxins in cereal grain, especially OTA (ochratoxin A) and DON (deoxynivalenol) by mixing with a solvent comprising water alcohol mixture, with 20-40% ethanol by volume.

公开(公告)号：US12111243B2

公开(公告)日：2024-10-08

申请号：US17779344

申请日：2020-12-01

Applicant: Foss Analytical A/S

Inventor： Christer Zoffmann Bisgaard ,  Anders Brask ,  Miguel Carro Temboury

IPC: G01N15/1404 ,  G01N15/1434

CPC classification number: G01N15/1404 ,  G01N15/1436 ,  G01N2015/1413

Abstract: A hydrodynamic focusing device comprises first and second flow channels; a wall at least partially defining an envelopment region connected in-line between the first and second flow channels which collectively define a flow direction extending therethrough; and a chimney comprising a body and a sample fluid inlet, extending from the wall and into the envelopment region. The sample fluid inlet faces at least partially perpendicular to the flow direction in the envelopment region, such that the sample fluid inlet is configured to supply a sample fluid into the envelopment region in a direction that is at least partially perpendicular to the flow direction. The body and the sample fluid inlet each have an elongate profile which has a rounded leading edge facing the first flow channel and opposing long edges connecting the leading and trailing edges and tapered towards the trailing edge.