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公开(公告)号：US20210023197A1
公开(公告)日：2021-01-28
申请号：US16676119
申请日：2019-11-06
申请人： FluGen, Inc.
IPC分类号： A61K39/145 , A61K39/12 , A61K39/00 , C12N7/00
摘要： Disclosed herein are compositions and methods related to mutant viruses, and in particular, mutant influenza viruses. The mutant viruses disclosed herein include a mutant M2 sequence, and are useful in immunogenic compositions, e.g., as vaccines. The mutant viruses disclosed herein including a mutant M2 sequence are also useful to deliver antigens to a subject, e.g., to induce an immune response to the antigen. Also disclosed herein are methods, compositions and cells for propagating the viral mutants, and methods, devices and compositions related to vaccination.
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公开(公告)号：US09757446B2
公开(公告)日：2017-09-12
申请号：US15125763
申请日：2015-03-13
申请人： FluGen, Inc.
IPC分类号： C12N7/00 , A61K39/145 , C12N15/86 , C07K14/005 , A61K39/00
CPC分类号： A61K39/145 , A61K39/00 , A61K39/0011 , A61K39/12 , A61K2039/5254 , A61K2039/5256 , A61K2039/54 , A61K2039/543 , A61K2039/545 , A61K2039/575 , C12N7/00 , C12N2760/16134 , C12N2760/16143 , C12N2760/16152
摘要： Disclosed herein are compositions and methods related to mutant viruses, and in particular, mutant influenza viruses. The mutant viruses disclosed herein include a mutant M2 sequence, and are useful in immunogenic compositions, e.g., as vaccines. The mutant viruses disclosed herein including a mutant M2 sequence are also useful to deliver antigens to a subject, e.g., to induce an immune response to the antigen. Also disclosed herein are methods, compositions and cells for propagating the viral mutants, and methods, devices and compositions related to vaccination.
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公开(公告)号：US11980662B2
公开(公告)日：2024-05-14
申请号：US17675297
申请日：2022-02-18
申请人： FluGen, Inc.
CPC分类号： A61K39/145 , A61K39/00 , A61K39/0011 , A61K39/12 , C12N7/00 , A61K2039/5254 , A61K2039/5256 , A61K2039/54 , A61K2039/543 , A61K2039/545 , A61K2039/575 , C12N2760/16134 , C12N2760/16143 , C12N2760/16152
摘要： Disclosed herein are compositions and methods related to mutant viruses, and in particular, mutant influenza viruses. The mutant viruses disclosed herein include a mutant M2 sequence, and are useful in immunogenic compositions, e.g., as vaccines. The mutant viruses disclosed herein including a mutant M2 sequence are also useful to deliver antigens to a subject, e.g., to induce an immune response to the antigen. Also disclosed herein are methods, compositions and cells for propagating the viral mutants, and methods, devices and compositions related to vaccination.
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公开(公告)号：US20230029543A1
公开(公告)日：2023-02-02
申请号：US17675297
申请日：2022-02-18
申请人： FluGen, Inc.
IPC分类号： A61K39/145 , A61K39/12 , A61K39/00 , C12N7/00
摘要： Disclosed herein are compositions and methods related to mutant viruses, and in particular, mutant influenza viruses. The mutant viruses disclosed herein include a mutant M2 sequence, and are useful in immunogenic compositions, e.g., as vaccines. The mutant viruses disclosed herein including a mutant M2 sequence are also useful to deliver antigens to a subject, e.g., to induce an immune response to the antigen. Also disclosed herein are methods, compositions and cells for propagating the viral mutants, and methods, devices and compositions related to vaccination.
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公开(公告)号：US11253584B2
公开(公告)日：2022-02-22
申请号：US16676119
申请日：2019-11-06
申请人： FluGen, Inc.
IPC分类号： A61K39/145 , C12N7/00 , A61K39/00 , A61K39/12 , C07K14/005
摘要： Disclosed herein are compositions and methods related to mutant viruses, and in particular, mutant influenza viruses. The mutant viruses disclosed herein include a mutant M2 sequence, and are useful in immunogenic compositions, e.g., as vaccines. The mutant viruses disclosed herein including a mutant M2 sequence are also useful to deliver antigens to a subject, e.g., to induce an immune response to the antigen. Also disclosed herein are methods, compositions and cells for propagating the viral mutants, and methods, devices and compositions related to vaccination.
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公开(公告)号：US20180043007A1
公开(公告)日：2018-02-15
申请号：US15681613
申请日：2017-08-21
申请人： FluGen, Inc.
IPC分类号： A61K39/145 , C12N7/00 , A61K39/00
CPC分类号： A61K39/145 , A61K39/00 , A61K39/0011 , A61K39/12 , A61K2039/5254 , A61K2039/5256 , A61K2039/54 , A61K2039/543 , A61K2039/545 , A61K2039/575 , C12N7/00 , C12N2760/16134 , C12N2760/16143 , C12N2760/16152
摘要： Disclosed herein are compositions and methods related to mutant viruses, and in particular, mutant influenza viruses. The mutant viruses disclosed herein include a mutant M2 sequence, and are useful in immunogenic compositions, e.g., as vaccines. The mutant viruses disclosed herein including a mutant M2 sequence are also useful to deliver antigens to a subject, e.g., to induce an immune response to the antigen. Also disclosed herein are methods, compositions and cells for propagating the viral mutants, and methods, devices and compositions related to vaccination.
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公开(公告)号：US20170106077A1
公开(公告)日：2017-04-20
申请号：US15125763
申请日：2015-03-13
申请人： FLUGEN, INC.
IPC分类号： A61K39/145 , C12N7/00 , A61K39/00
CPC分类号： A61K39/145 , A61K39/00 , A61K39/0011 , A61K39/12 , A61K2039/5254 , A61K2039/5256 , A61K2039/54 , A61K2039/543 , A61K2039/545 , A61K2039/575 , C12N7/00 , C12N2760/16134 , C12N2760/16143 , C12N2760/16152
摘要： Disclosed herein are compositions and methods related to mutant viruses, and in particular, mutant influenza viruses. The mutant viruses disclosed herein include a mutant M2 sequence, and are useful in immunogenic compositions, e.g., as vaccines. The mutant viruses disclosed herein including a mutant M2 sequence are also useful to deliver antigens to a subject, e.g., to induce an immune response to the antigen. Also disclosed herein are methods, compositions and cells for propagating the viral mutants, and methods, devices and compositions related to vaccination.
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