公开(公告)号：US20200308533A1

公开(公告)日：2020-10-01

申请号：US16880787

申请日：2020-05-21

申请人： FloDesign Sonics, Inc.

发明人： Bart Lipkens ,  Erik Miller ,  Benjamin Ross-Johnsrud ,  Walter M. Presz, JR. ,  Kedar Chitale ,  Thomas J. Kennedy, III ,  Lauryn Winiarski

IPC分类号： C12M1/00 ,  B01D17/04 ,  B01D17/06 ,  B01D21/28 ,  B06B1/06 ,  C12M1/26 ,  C12M1/42 ,  C12N13/00

摘要： Acoustic perfusion devices for separating biological cells from other material in a fluid mixture are disclosed. The devices include an inlet port, an outlet port, and a collection port that are connected to an acoustic chamber. An ultrasonic transducer creates an acoustic standing wave in the acoustic chamber that permits a continuous flow of fluid to be recovered through the collection port while keeping the biological cells within the acoustic chamber to be returned to the bioreactor from which the fluid mixture is being drawn.

公开(公告)号：US10662402B2

公开(公告)日：2020-05-26

申请号：US15696176

申请日：2017-09-05

申请人： FloDesign Sonics, Inc.

发明人： Bart Lipkens ,  Erik Miller ,  Benjamin Ross-Johnsrud ,  Walter M. Presz, Jr. ,  Kedar Chitale ,  Thomas J. Kennedy, III ,  Lauryn Winiarski

IPC分类号： B01D17/04 ,  C12M1/00 ,  B01D17/06 ,  B01D21/28 ,  B06B1/06 ,  C12M1/26 ,  C12M1/42 ,  C12N13/00 ,  H01L41/09

摘要： Acoustic perfusion devices for separating biological cells from other material in a fluid mixture are disclosed. The devices include an inlet port, an outlet port, and a collection port that are connected to an acoustic chamber. An ultrasonic transducer creates an acoustic standing wave in the acoustic chamber that permits a continuous flow of fluid to be recovered through the collection port while keeping the biological cells within the acoustic chamber to be returned to the bioreactor from which the fluid mixture is being drawn.