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公开(公告)号：US20230133508A1
公开(公告)日：2023-05-04
申请号：US18090794
申请日：2022-12-29
申请人： FUJIFILM Corporation
IPC分类号： A01N1/02
摘要： According to the present invention, there are provided a chamber for transplantation, as a planar chamber for transplantation which has a structure in which membranes for immunoisolation face each other, and which is capable of stably enclosing a biological constituent, including a membrane for immunoisolation at a boundary between an inside and an outside of the chamber for transplantation, in which the membranes for immunoisolation which face each other have joint portions that are joined to each other, an interior space includes a point at a distance of 10 mm or longer from any position of the joint portion, and the membrane for immunoisolation has flexibility that allows a distance of 1 mm to 13 mm as the following distance: in a case where a portion of 10 mm from a side surface of one short side of a 10 mm×30 mm rectangular test piece of the membrane for immunoisolation is vertically sandwiched between flat plates, and the flat plates are placed horizontally, a distance between a horizontal plane including a center plane in a thickness direction of the sandwiched portion of the membrane for immunoisolation, and a part, which is farthest from the horizontal plane, of a residual 20 mm-portion projecting from the flat plate; and a device for transplantation including the chamber for transplantation enclosing a biological constituent therein.
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公开(公告)号：US20220023226A1
公开(公告)日：2022-01-27
申请号：US17497289
申请日：2021-10-08
申请人： FUJIFILM Corporation
发明人： Yusuke MOCHIZUKI , Ryuta TAKEGAMI
摘要： There is provided a production method for a microcapsule in which cells are encapsulated with alginic acid and a polycation, the method including dropwise adding a cell suspension containing cells and alginic acid into a calcium ion-containing solution to obtain a liquid droplet in which the cells are encapsulated in alginic acid, and immersing the liquid droplet in a coating liquid containing a polycation, to obtain the microcapsule, where the coating liquid contains a calcium ion or a barium ion at a concentration of 0.1 mM or more and 50.0 mM or less. According to the production method of the present invention, it is possible to produce a microcapsule having a uniform shape and particle size.
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3.发明申请公开(公告)号：US20190262122A1
公开(公告)日：2019-08-29
申请号：US16409241
申请日：2019-05-10
申请人： FUJIFILM Corporation
IPC分类号： A61F2/02 , A61L27/16 , A61L27/18 , A61L27/38 , A61L31/04 , A61L31/14 , A61K35/12 , A61K38/28
摘要： According to the present invention, there are provided a membrane for immunoisolation, including: a porous membrane that contains a polymer, in which the porous membrane includes a layered compact portion where a pore diameter is the smallest within the membrane, and a pore diameter continuously increases in a thickness direction from the compact portion toward at least one surface of the porous membrane; a chamber for transplantation for enclosing a biological constituent therein, including the above-described membrane for immunoisolation on at least a part of a surface forming an inside and an outside of the chamber for transplantation; and a device for transplantation, including the above-described chamber for transplantation enclosing the biological constituent therein. In the membrane for immunoisolation of the present invention which can be manufactured at low costs, a deterioration in substance permeability is unlikely to occur.
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公开(公告)号：US20190076777A1
公开(公告)日：2019-03-14
申请号：US16186606
申请日：2018-11-12
申请人： FUJIFILM Corporation
发明人： Yusuke MOCHIZUKI , Atsushi MUKAI , Motoi HARADA , Makoto SAWADA
IPC分类号： B01D53/22 , B01D71/32 , B01D71/40 , B01D71/10 , B01D71/64 , B01D69/12 , B01D71/70 , B01D69/02
摘要： A gas separation membrane, the gas separation membrane module, and the gas separation device include a first separation layer, and a second separation layer, the first separation layer has an Si/C ratio of 0.3 or less, the Si/C ratio being a ratio of the number of silicon atoms to the number of carbon atoms at the interface of the first separation layer on the second separation layer side, the second separation layer has a maximum value of an F/C ratio of 0.20 or more, the F/C ratio being a ratio of the number of fluorine atoms to the number of carbon atoms, and an Si/C ratio of 0.3 or less in a portion where the F/C ratio is maximum.
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公开(公告)号：US20220241211A1
公开(公告)日：2022-08-04
申请号：US17677045
申请日：2022-02-22
申请人： FUJIFILM Corporation
发明人： Kentaro NAKAMURA , Ryo KOGAWA , Ryuta TAKEGAMI , Yusuke MOCHIZUKI
摘要： An object of the present invention is to provide a composition containing at least microcapsules and cell structures, where the composition can exhibit a high treatment effect in a case of being transplanted into a living body. There is provided a composition including at least (a) a microcapsule containing a polymer hydrogel; and (b) a cell structure containing a biocompatible polymer block and a cell, in which a plurality of biocompatible polymer blocks are arranged in gaps between a plurality of cells, where at least a part of the cell structures are encapsulated in the microcapsules.
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6.发明申请公开(公告)号：US20190262509A1
公开(公告)日：2019-08-29
申请号：US16408894
申请日：2019-05-10
申请人： FUJIFILM Corporation
IPC分类号： A61L31/14 , A61L27/16 , A61F2/02 , A61L27/18 , A61L27/38 , A61L31/16 , A61L31/04 , A61K9/00 , A61K38/28
摘要： According to the present invention, there is provided a membrane for immunoisolation, including a porous membrane that contains a polymer, in which Formulas (I) and (II) are satisfied for at least one surface of the porous membrane, B/A≤0.7 (I) and A≥0.015 (II) (in the formula, A represents a ratio of an N element to a C element on a surface of the membrane, and B represents a ratio of the N element to the C element at a depth of 30 nm from the surface of the membrane); a chamber for transplantation for enclosing a biological constituent therein, including the above-described membrane for immunoisolation on at least a part of a surface forming an inside and an outside of the chamber for transplantation; and a device for transplantation includes the above-described chamber for transplantation enclosing the above-described biological constituent therein. The membrane for immunoisolation of the present invention has a high bioaffinity.
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7.发明申请公开(公告)号：US20170182469A1
公开(公告)日：2017-06-29
申请号：US15458407
申请日：2017-03-14
申请人： FUJIFILM Corporation
发明人： Yusuke MOCHIZUKI , Makoto SAWADA , Takeshi NARITA , Shigehide ITOU , Hiroyuki NODA , Atsushi MUKAI
摘要： Provided are a gas separation membrane which has a resin layer containing a compound having a siloxane bond, in which the resin layer containing a compound having a siloxane bond satisfies Expressions 1 and 2, and at least one of gas permeability or gas separation selectivity is high under high pressure; a method of producing a gas separation membrane; a gas separation membrane module; and a gas separator. 0.9≧A/B≧0.55 Expression 1 B≧1.7 Expression 2 In the expressions, A represents an O/Si ratio that is a ratio of the number of oxygen atoms relative to the number of silicon atoms contained in the resin layer containing a compound having a siloxane bond at a depth of 10 nm from the surface of the resin layer containing a compound having a siloxane bond, and B represents an O/Si ratio that is a ratio of the number of oxygen atoms relative to the number of silicon atoms in the surface of the resin layer containing a compound having a siloxane bond.
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8.发明申请公开(公告)号：US20130284022A1
公开(公告)日：2013-10-31
申请号：US13933127
申请日：2013-07-02
申请人： FUJIFILM CORPORATION
CPC分类号： B01D53/228 , B01D67/0002 , B01D67/0011 , B01D69/142 , B01D2257/504 , B01D2323/30 , B01D2323/42 , C08K3/26 , C08K13/02 , C08K2003/262 , C08L5/12 , C08L29/04 , C08L33/02 , C08L67/00 , C08L101/14 , Y02C10/10 , Y02P20/152
摘要： A composition for forming a carbon dioxide separation membrane, which includes a water-absorbing polymer, a carbon dioxide carrier, and a polysaccharide, is disclosed.
摘要翻译： 公开了一种用于形成二氧化碳分离膜的组合物，其包括吸水聚合物，二氧化碳载体和多糖。
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公开(公告)号：US20240053099A1
公开(公告)日：2024-02-15
申请号：US18474051
申请日：2023-09-25
申请人： FUJIFILM Corporation
发明人： Yusuke MOCHIZUKI , Hideo FUSHIMI , Nobuhiko KATO
摘要： The present disclosure provides a freeze-drying container which includes a container body storing liquid to be freeze-dried and a first heat transfer body being in contact with the liquid to be freeze-dried and a cold source and in which the container body is a non-heat transfer body or a second heat transfer body of which at least a part is in contact with a liquid surface of the liquid to be freeze-dried and the cold source and at least one of a first shortest distance between an arbitrary point on the liquid surface of the liquid to be freeze-dried and the first heat transfer body or a second shortest distance in the liquid surface between the arbitrary point on the liquid surface of the liquid to be freeze-dried and the second heat transfer body is 20 mm or less.
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公开(公告)号：US20190091635A1
公开(公告)日：2019-03-28
申请号：US16202103
申请日：2018-11-28
申请人： FUJIFILM Corporation
发明人： Atsushi MUKAI , Yusuke MOCHIZUKI
摘要： A gas separation membrane, the gas separation membrane module, and the gas separation device each have a support, a resin layer, a separation layer, and a protective layer in this order, in which the resin layer includes a compound having a siloxane bond, the protective layer is in direct contact with the separation layer, a composition of the protective layer is different from a composition of the resin layer, the composition of the protective layer is different from a composition of the separation layer, and the separation layer has a maximum value of a silicon atom content of 2 atomic % or less in a composition of a half area on a side of the protective layer in a thickness direction.
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