公开(公告)号：US20180363014A1

公开(公告)日：2018-12-20

申请号：US16007523

申请日：2018-06-13

申请人： Evonik Degussa GmbH

发明人： Kornelia VOSS ,  Michaela VOSS ,  Georg THIERBACH

IPC分类号： C12P13/06 ,  C12N15/77 ,  C12N9/44 ,  C12P13/08

CPC分类号： C12P13/06 ,  C07K2319/10 ,  C12N1/20 ,  C12N9/2451 ,  C12N15/77 ,  C12P13/04 ,  C12P13/08 ,  C12P19/02 ,  C12P19/14 ,  C12P19/30 ,  C12P19/38 ,  C12P25/00 ,  C12Y302/0101 ,  C12Y302/01033

摘要： The present invention relates to polynucleotides encoding novel fusion polypeptides essentially composed of a signal peptide for membrane translocation and a polypeptide providing α-1,6-glucosidase activity and to bacteria containing said polynucleotides. The invention further relates to methods for producing fine chemicals using media containing isomaltose and/or panose as carbon source.

公开(公告)号：US20190185890A1

公开(公告)日：2019-06-20

申请号：US16219718

申请日：2018-12-13

申请人： Evonik Degussa GmbH

发明人： Kornelia VOSS ,  Georg THIERBACH ,  Thomas BEKEL

IPC分类号： C12P13/08 ,  C12N15/77 ,  C12N15/10 ,  C12R1/15

CPC分类号： C12P13/08 ,  C12N9/0006 ,  C12N15/1024 ,  C12N15/77 ,  C12R1/15 ,  C12Y101/05004

摘要： The present invention makes available novel L-lysine excreting bacteria of the species Corynebacterium glutamicum, having the ability to excrete L-lysine, containing in their chromosome a polynucleotide encoding a polypeptide having the activity of a malate:quinone reductase wherein the amino acid at position 228 of the amino acid sequence of the polypeptide contains any proteinogenic amino acid different from valine and a method for producing L-lysine using such bacteria.