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公开(公告)号:US20240366372A1
公开(公告)日:2024-11-07
申请号:US18626109
申请日:2024-04-03
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor: Matthew Michael Becerra , Kevin M. Stewart , Richard D. White , David Robert Landon , Jonathan Yeh , Harish Manickam Srinimukesh , Matthew A. Peterson , Munci Muhsin Inonu , Christopher Aguayo , Parth Himanshu Parikh
IPC: A61F2/24
Abstract: A system including a delivery apparatus, a crimping device, and a loading assembly. The crimping device includes a housing disposed over a distal end portion of the delivery apparatus for receiving a radially expandable and compressible prosthetic heart valve. The housing includes a funnel segment, a pusher member, and an actuator releasably coupled to the pusher member. Movement of the actuator causes the pusher member to advance the prosthetic heart valve through the funnel segment for radially compressing at least a portion of the prosthetic heart valve. Compression of the prosthetic heart valve facilitates secure attachment of the prosthetic heart valve to the delivery apparatus. The loading assembly can include an additional funnel member for fully crimping and loading the prosthetic heart valve into the delivery apparatus for advancement through a patient's vasculature.
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公开(公告)号:US20240299166A1
公开(公告)日:2024-09-12
申请号:US18664760
申请日:2024-05-15
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor: Alexander H. Cooper , Juliet Laura Schwartz , Hannah Marie Glas , Matthew Michael Becerra , David Robert Landon , Siddharth Vad , Taylor Jacob Scheinblum , Matthew A. Peterson , Wei Gan
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2436 , A61F2220/0016 , A61F2230/0041 , A61F2230/0093 , A61F2250/001
Abstract: A prosthetic valve includes an expandable valve frame and leaflets supported therein. A plurality of elongate anchor arms extends from an outlet end portion of the valve frame. Each elongate anchor arm includes anchoring protrusions, such as barbs, for engaging surrounding tissue. During delivery to the treatment site, the anchoring protrusions face inwardly. When released from the delivery catheter, the anchoring arms evert such that the anchoring protrusions reverse orientation and face outwardly. In this position, the protrusions can engage surrounding tissue and thereby secure the prosthetic valve within a native heart valve.
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公开(公告)号:US20230200980A1
公开(公告)日:2023-06-29
申请号:US18111278
申请日:2023-02-17
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor: Matthew A. Peterson , Siddharth Vad , Scott Louis Shary , Taylor Jacob Scheinblum , Kevin M. Golemo , Yevgeniy Davidovich Kaufman , David Robert Landon
IPC: A61F2/24
CPC classification number: A61F2/2409 , A61F2220/0008 , A61F2250/0039 , A61F2250/007
Abstract: Apparatuses, systems, and methods for prosthetic valves. Embodiments of prosthetic valves may include sealing bodies configured for an anchor to at least partially pass through. The pass through may allow for the sealing body to seal to a portion of a patient's heart in the event of a miscapture of a leaflet by the anchor. Embodiments may include modular valve systems and prosthetic valves including anchors for coupling to chordae, trabeculae, or papillary structures of a patient's heart. Embodiments may include prosthetic valves including anchors for engaging calcification of a patient's native valve.
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公开(公告)号:US11684471B2
公开(公告)日:2023-06-27
申请号:US16902773
申请日:2020-06-16
Applicant: Edwards Lifesciences Corporation
Inventor: Alexander H. Cooper , Matthew A. Peterson , William C. Brunnett
CPC classification number: A61F2/2418 , A61F2/2409 , A61F2/2436 , A61F2002/9534 , A61F2220/0008 , A61F2230/005 , A61F2230/0065 , A61F2230/0078
Abstract: Embodiments of a prosthetic heart valve comprise an annular main body, an atrial cap extending radially outwardly from the atrial end of the main body, and a plurality of ventricular anchors extending outwardly from the ventricular end of the main body. Each ventricular anchor can have a proximal end portion connected to the ventricular end, an intermediate portion extending away from the atrial end and then back toward the atrial so as to define a first bend, and a free distal end portion that extends from the intermediate portion. The distal end portion can comprise a first section, a second section, and a second bend between the first and second sections, the first section extending from the intermediate portion in a direction toward the atrial end and radially away from the main body.
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公开(公告)号:US20230157814A1
公开(公告)日:2023-05-25
申请号:US18099209
申请日:2023-01-19
Applicant: Edwards Lifesciences Corporation
Inventor: Travis Zenyo Oba , Matthew A. Peterson , Glen T. Rabito , Alexander H. Cooper , David Robert Landon , J. Brent Ratz , Seung-Beom Yi
CPC classification number: A61F2/2409 , A61F2/2418 , A61L27/04 , A61L27/3625 , A61F2/2412 , A61F2/2436 , A61F2220/0008 , A61F2220/0075 , A61F2230/0093 , A61F2250/0018 , A61F2250/0039 , A61F2250/0063 , A61L2430/20
Abstract: A replacement mitral valve prosthesis includes a support structure and a valve body having three flexible leaflets. The support structure preferably includes an internal valve frame and an external sealing frame. The valve frame supports the flexible leaflets. The sealing frame is adapted to conform to the shape of the native mitral valve annulus. The sealing frame may be coupled to an inlet end of the valve frame, an outlet end of the valve frame, or both. A plurality of anchors is coupled to the outlet end of the valve frame. The anchors extend radially outwardly for placement behind native leaflets. The prosthesis preferably includes a skirt disposed along an exterior of the external sealing frame. The prosthesis is collapsible for delivery into the heart via a delivery catheter. The prosthesis is configured to self-expand for deployment in the heart when released from the delivery catheter.
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公开(公告)号:US20220104940A1
公开(公告)日:2022-04-07
申请号:US17553566
申请日:2021-12-16
Applicant: Edwards Lifesciences Corporation
Inventor: Matthew A. Peterson , Seung-Beom Yi , Siddharth Vad , Travis Zenyo Oba , Lauren R. Freschauf , Amanda French , Yaron Keidar , Yuanlong Du , Gregory Bak-Boychuk , Kevin M. Golemo , Alexander H. Cooper
IPC: A61F2/24
Abstract: A prosthesis can be configured to grasp intralumenal tissue when deployed within a body cavity and prevent axial flow of fluid around an exterior of the prosthesis. The prosthesis can include an expandable frame configured to radially expand and contract for deployment within the body cavity and a valve body. The expandable frame can include a frame body and a supplemental frame. The valve body can include a plurality of leaflets and one or more intermediate components. The one or more intermediate components can couple at least a portion of the leaflets to the expandable frame. The prosthesis can include an annular flap positioned around an exterior of the expandable frame.
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公开(公告)号:US20220006850A1
公开(公告)日:2022-01-06
申请号:US17387121
申请日:2021-07-28
Applicant: Edwards Lifesciences Corporation
Inventor: Alexander H. Cooper , Juliet Laura Schwartz , Wendy Vo Pham , Hieu Minh Luong , Julio Cesar Sanchez , Matthew A. Peterson , J. Brent Ratz , Lisong Ai
Abstract: A method for replacing a native heart valve includes advancing a delivery catheter having a valve prosthesis disposed along a distal end portion thereof, wherein the valve includes an inner frame having an hourglass shape and an outer sealing frame connected to and surrounding the inner frame. A valve body is mounted within the inner frame and includes a plurality of leaflets. The leaflets have longitudinal curvatures when in an open position, wherein the curvatures are shaped for conforming to the curved interior surface of the inner frame. This combination of features reduces the possibility of blood stagnating between the leaflets and inner frame, which reduces the possibility of thrombus formation.
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公开(公告)号:US20190328515A1
公开(公告)日:2019-10-31
申请号:US16506886
申请日:2019-07-09
Applicant: Edwards Lifesciences Corporation
Inventor: Matthew A. Peterson , Seung-Beom Yi , Siddharth Vad , Travis Zenyo Oba , Lauren R. Freschauf , Amanda French , Yaron Keidar , Yuanlong Du , Gregory Bak-Boychuk , Kevin M. Golemo , Alexander H. Cooper
IPC: A61F2/24
Abstract: A heart valve prosthesis for replacing a native mitral valve includes a self-expanding frame with a plurality of anchoring members disposed along the lower region. A valve body is positioned within the self-expanding frame and includes a plurality of leaflets configured to allow blood flow through the self-expanding frame in only one direction. A skirt surrounds the self-expanding frame and is spaced apart therefrom for contacting surrounding tissue and impeding blood flow around the self-expanding frame. The skirt may be reinforced with wires to help maintain a desired shape. The leaflets in the valve body are preferably connected to the self-expanding frame through one or more intermediate components such that the valve body is spaced radially inwardly from an inner surface of the self-expanding frame.
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公开(公告)号:US20180055629A1
公开(公告)日:2018-03-01
申请号:US15687184
申请日:2017-08-25
Applicant: Edwards Lifesciences Corporation
Inventor: Travis Zenyo Oba , Matthew A. Peterson , Glen T. Rabito , Alexander H. Cooper , David Robert Landon , J. Brent Ratz , Seung-Beom Yi
CPC classification number: A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2/2436 , A61F2220/0008 , A61F2220/0075 , A61F2230/0093 , A61F2250/0018 , A61F2250/0039 , A61F2250/0063 , A61L27/04 , A61L27/3625 , A61L2430/20
Abstract: A replacement mitral valve prosthesis includes a support structure and a valve body having three flexible leaflets. The support structure preferably includes an internal valve frame and an external sealing frame. The valve frame supports the flexible leaflets. The sealing frame is adapted to conform to the shape of the native mitral valve annulus. The sealing frame may be coupled to an inlet end of the valve frame, an outlet end of the valve frame, or both. A plurality of anchors are coupled to the outlet end of the valve frame. The anchors extend radially outwardly for placement behind native leaflets. The prosthesis preferably includes a skirt disposed along an exterior of the external sealing frame. The prosthesis is collapsible for delivery into the heart via a delivery catheter. The prosthesis is configured to self-expand for deployment in the heart when released from the delivery catheter.
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公开(公告)号:US20240307175A1
公开(公告)日:2024-09-19
申请号:US18673188
申请日:2024-05-23
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor: Alexander H. Cooper , Juliet Laura Schwartz , Hannah Marie Glas , Matthew Michael Becerra , David Robert Landon , Siddharth Vad , Taylor Jacob Scheinblum , Matthew A. Peterson , Wei Gan
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2433 , A61F2220/0016 , A61F2220/0075 , A61F2230/0069 , A61F2250/006 , A61F2250/0068
Abstract: Apparatuses, systems, and methods for prosthetic valves. Examples of prosthetic valves may be configured to anchor to an interior surface of a heart valve. Such prosthetic valves, in examples, may include a single frame that supports a plurality of prosthetic valve leaflets. In examples, multiple frames may be utilized to anchor to a heart valve and one or more of the frames may support a plurality of prosthetic valve leaflets.
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