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    Method of treating a defective mitral valve by filling gap
    1.
    发明授权
    Method of treating a defective mitral valve by filling gap 有权

    公开(公告)号：US10799361B2

    公开(公告)日：2020-10-13

    申请号：US16803455

    申请日：2020-02-27

    Applicant: Edwards Lifesciences Corporation

    Inventor： David L. Hauser ,  Jan Otto Solem ,  David Alon

    IPC: A61F2/24

    Abstract: A method of treating a defective mitral valve includes inserting a delivery catheter through a small incision in a patient's groin, wherein the delivery catheter has a prosthetic device positioned along a distal end thereof. The prosthetic device includes an insert member and an anchoring member, wherein the insert member is made from a shape memory material and is surrounded by a biocompatible fabric outer layer. The insert member is positioned within a mitral valve and self-expands in a gap between the native leaflets. The anchoring member is attached to surrounding tissue. After deployment of the prosthetic device, the native leaflets of the mitral valve form a tight seal against the biocompatible fabric outer layer and the insert member fills the gap between the native leaflets of the mitral valve for preventing regurgitation during ventricular systole.

    Cardiac valve repair devices configured for percutaneous delivery
    2.
    发明授权
    Cardiac valve repair devices configured for percutaneous delivery 有权

    公开(公告)号：US10278819B2

    公开(公告)日：2019-05-07

    申请号：US15167760

    申请日：2016-05-27

    Applicant: Edwards Lifesciences Corporation

    Inventor： David M. Taylor ,  Tri D. Tran ,  Sean Chow ,  David L. Hauser ,  Pui Tong Ho ,  Alexander H. Cooper

    IPC: A61F2/24

    Abstract: Disclosed herein are devices for improving coaption of the mitral valve leaflets to reduce or eliminate mitral valve regurgitation. The devices may be used to perform mitral valve annuloplasty, or to serve as a docking station for a transcatheter prosthetic heart valve. The various embodiments of devices are configured for percutaneous and, in some cases, transvascular delivery. Delivery systems useful for routing the devices to the mitral valve are also disclosed, including catheters, balloons and/or mechanical expansion systems. The devices themselves include at least one tissue penetrating member. Methods of delivery include partially embedding the devices in the mitral valve annulus via at least one tissue penetrating member. Tissue penetrating members may be embedded into the tissue in a simultaneous or a nearly simultaneous fashion. Upon embedding, the devices employ various expansion and/or contraction features to adjust the mitral valve diameter. Adjustments may continue until the leaflets fully coapt and the problem of mitral regurgitation is reduced or eliminated.

    Cardiac valve repair devices configured for percutaneous delivery
    5.
    发明授权
    Cardiac valve repair devices configured for percutaneous delivery 有权

    公开(公告)号：US11166817B2

    公开(公告)日：2021-11-09

    申请号：US16358480

    申请日：2019-03-19

    Applicant: Edwards Lifesciences Corporation

    Inventor： David M. Taylor ,  Tri D. Tran ,  Sean Chow ,  David L. Hauser ,  Pui Tong Ho ,  Alexander H. Cooper

    IPC: A61F2/24

    Abstract: Disclosed herein are devices for improving coaption of the mitral valve leaflets to reduce or eliminate mitral valve regurgitation. The devices may be used to perform mitral valve annuloplasty, or to serve as a docking station for a transcatheter prosthetic heart valve. The various embodiments of devices are configured for percutaneous and, in some cases, transvascular delivery. Delivery systems useful for routing the devices to the mitral valve are also disclosed, including catheters, balloons and/or mechanical expansion systems. The devices themselves include at least one tissue penetrating member. Methods of delivery include partially embedding the devices in the mitral valve annulus via at least one tissue penetrating member. Tissue penetrating members may be embedded into the tissue in a simultaneous or a nearly simultaneous fashion. Upon embedding, the devices employ various expansion and/or contraction features to adjust the mitral valve diameter. Adjustments may continue until the leaflets fully coapt and the problem of mitral regurgitation is reduced or eliminated.

    CARDIAC VALVE REPAIR DEVICES CONFIGURED FOR PERCUTANEOUS DELIVERY
    7.
    发明申请
    CARDIAC VALVE REPAIR DEVICES CONFIGURED FOR PERCUTANEOUS DELIVERY 审中-公开
    CARDIAC阀维修设备配置用于PERCUTANEOUS DELIVERY

    公开(公告)号：US20160346084A1

    公开(公告)日：2016-12-01

    申请号：US15167760

    申请日：2016-05-27

    Applicant: Edwards Lifesciences Corporation

    Inventor： David M. Taylor ,  Tri D. Tran ,  Sean Chow ,  David L. Hauser ,  Pui Tong Ho ,  Alexander H. Cooper

    IPC: A61F2/24

    CPC classification number: A61F2/2445 ,  A61F2/2418 ,  A61F2/243 ,  A61F2/2433 ,  A61F2/2448 ,  A61F2/2466 ,  A61F2210/0014 ,  A61F2250/0014

    Abstract: Disclosed herein are devices for improving coaption of the mitral valve leaflets to reduce or eliminate mitral valve regurgitation. The devices may be used to perform mitral valve annuloplasty, or to serve as a docking station for a transcatheter prosthetic heart valve. The various embodiments of devices are configured for percutaneous and, in some cases, transvascular delivery. Delivery systems useful for routing the devices to the mitral valve are also disclosed, including catheters, balloons and/or mechanical expansion systems. The devices themselves include at least one tissue penetrating member. Methods of delivery include partially embedding the devices in the mitral valve annulus via at least one tissue penetrating member. Tissue penetrating members may be embedded into the tissue in a simultaneous or a nearly simultaneous fashion. Upon embedding, the devices employ various expansion and/or contraction features to adjust the mitral valve diameter. Adjustments may continue until the leaflets fully coapt and the problem of mitral regurgitation is reduced or eliminated.

    Abstract translation: 本文公开了用于改善二尖瓣小叶的缩小以减少或消除二尖瓣反流的装置。 该装置可用于进行二尖瓣瓣膜成形术，或用作经导管假体心脏瓣膜的对接站。 装置的各种实施例被配置用于经皮的，在一些情况下被配置为经血管递送。 还公开了用于将装置路由到二尖瓣的输送系统，包括导管，球囊和/或机械膨胀系统。 装置本身包括至少一个组织穿透构件。 递送方法包括通过至少一个组织穿透构件将装置部分地嵌入二尖瓣环中。 组织穿透构件可以以同时或几乎同时的方式嵌入组织中。 在嵌入时，装置采用各种膨胀和/或收缩特征来调节二尖瓣直径。 调整可能会继续，直到传单完全适应，并减少或消除二尖瓣反流问题。

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