公开(公告)号：US20050082491A1

公开(公告)日：2005-04-21

申请号：US10687550

申请日：2003-10-15

申请人： Edward Seppi ,  Larry Partain ,  George Zentai

发明人： Edward Seppi ,  Larry Partain ,  George Zentai

IPC分类号： G01T1/20 ,  G01T1/24 ,  G01T1/36 ,  H01L27/146

CPC分类号： G01T1/362 ,  A61B5/7289 ,  A61B5/7292 ,  A61B6/032 ,  A61B6/4035 ,  A61B6/405 ,  A61B6/4233 ,  A61B6/4241 ,  A61B6/4441 ,  A61B6/481 ,  A61B6/482 ,  A61B6/502 ,  A61B6/5288 ,  A61B6/541 ,  G01T1/2018 ,  H01L27/14667 ,  H01L27/14676

摘要： A radiation projection detector includes a conversion layer configured to generate light photons in response to a radiation, the conversion layer having a plurality of first conversion elements and a plurality of second conversion elements, and a photo detector array aligned with the conversion panel, wherein each of the first conversion elements has a first radiation conversion characteristic, and each of the second conversion elements has a second radiation conversion characteristic. A radiation projection detector includes a photoconductor layer configured to generate charges in response to radiation, the photoconductor layer having a plurality of first photoconductor elements and a plurality of second photoconductor elements, and a detector array aligned with the photoconductor layer, wherein each of the first photoconductor elements has a first charge generating characteristic, and each of the second photoconductor elements has a second charge generating characteristic.

摘要翻译： 辐射投影检测器包括被配置为响应于辐射而产生光子的转换层，所述转换层具有多个第一转换元件和多个第二转换元件以及与转换面板对准的光电检测器阵列，其中每个 的第一转换元件具有第一辐射转换特性，并且每个第二转换元件具有第二辐射转换特性。 辐射投影检测器包括被配置为响应于辐射产生电荷的光电导体层，所述光电导体层具有多个第一光电导体元件和多个第二光电导体元件，以及与所述光电导体层对准的检测器阵列，其中所述第一 光电导体元件具有第一电荷产生特性，并且每个第二感光体元件具有第二电荷产生特性。

公开(公告)号：US20050084060A1

公开(公告)日：2005-04-21

申请号：US10687522

申请日：2003-10-15

申请人： Edward Seppi ,  Larry Partain ,  Michael Green ,  Gary Virshup

发明人： Edward Seppi ,  Larry Partain ,  Michael Green ,  Gary Virshup

IPC分类号： A61B6/00 ,  A61B6/03 ,  G01N23/04 ,  G21K1/12 ,  G01N23/00 ,  H05G1/60

CPC分类号： A61B6/405 ,  A61B5/7289 ,  A61B5/7292 ,  A61B6/032 ,  A61B6/0435 ,  A61B6/4035 ,  A61B6/4042 ,  A61B6/4241 ,  A61B6/4441 ,  A61B6/4488 ,  A61B6/466 ,  A61B6/481 ,  A61B6/482 ,  A61B6/502 ,  A61B6/504 ,  A61B6/5288 ,  A61B6/541 ,  G01N23/046 ,  G01N2223/419 ,  G01N2223/612 ,  H01J2235/081

摘要： A method of generating images of a portion of a body includes introducing a contrast agent into the body, generating a first set of image data using radiation at a first energy level after the contrast agent is introduced into the body, generating a second set of image data using radiation at a second energy level after the contrast agent is introduced into the body, and creating a volumetric composite image using the first and the second sets of image data.

摘要翻译： 产生身体部分的图像的方法包括将造影剂引入体内，在将造影剂引入体内之后，以第一能量级别的辐射产生第一组图像数据，产生第二组图像 在将造影剂引入身体之后，使用在第二能量级别的辐射的数据，以及使用第一和第二组图像数据创建体积合成图像。

公开(公告)号：US06486808B1

公开(公告)日：2002-11-26

申请号：US09978727

申请日：2001-10-16

申请人： Edward Seppi ,  Edward Shapiro ,  George Zentai ,  Richard Colbeth

发明人： Edward Seppi ,  Edward Shapiro ,  George Zentai ,  Richard Colbeth

IPC分类号： H03M184

CPC分类号： H03M1/129 ,  H03M1/18 ,  H04N5/235 ,  H04N5/243 ,  H04N5/32

摘要： A preamplifier stage with dynamically controllable signal gain in a data signal processing circuit that includes a downstream analog-to-digital signal converter. The level of the data signal subsequent to its preamplification is monitored and the gain of the preamplifier stage is dynamically adjusted in response to such data signal transcending one or more predetermined thresholds. Hence, the effective dynamic range of the preamplifier stage is extended, thereby also effectively extending the dynamic range of the overall system beyond that to which it would have otherwise been limited by the dynamic range of the analog-to-digital signal converter. In accordance with a preferred embodiment of the invention, such a preamplifier is used in an X-ray imaging system such as that using flat panel solid state imaging devices.

摘要翻译： 一种在包括下游模拟 - 数字信号转换器的数据信号处理电路中具有动态可控的信号增益的前置放大器级。 监视其预放大之后的数据信号的电平，并响应于超过一个或多个预定阈值的这种数据信号来动态调整前置放大器级的增益。 因此，前置放大器级的有效动态范围被扩展，从而也有效地扩展了整个系统的动态范围，超出了其将被模拟 - 数字信号转换器的动态范围所限制的范围。 根据本发明的优选实施例，这种前置放大器用于诸如使用平板固态成像装置的X射线成像系统中。

公开(公告)号：US07660384B2

公开(公告)日：2010-02-09

申请号：US12126224

申请日：2008-05-23

申请人： Larry Partain ,  Stavros Prionas ,  Edward Seppi ,  Robert Sutherland ,  David Humber ,  Hassan Mostafavi ,  Felix Fernando ,  John Boone

发明人： Larry Partain ,  Stavros Prionas ,  Edward Seppi ,  Robert Sutherland ,  David Humber ,  Hassan Mostafavi ,  Felix Fernando ,  John Boone

IPC分类号： A61B6/04

CPC分类号： A61B6/4241 ,  A61B6/032 ,  A61B6/4085 ,  A61B6/482 ,  A61B6/502 ,  A61B6/507

摘要： A method of imaging a patient's uncompressed region of interest using X-ray cone beam computed tomography or cone beam digital tomography comprises the step of introducing an effective amount of a contrast agent to the uncompressed region of interest. A system for imaging a patient's uncompressed region of interest using cone beam computed tomography (CBCT) or cone beam digital tomography (CBDT) comprises an X-ray source transmitting an X-ray to the uncompressed region of interest, an image acquisition system acquiring a plurality of two-dimensional projection images data for a CBCT or CBDT data set with at least one of the projection images acquired in 35 milliseconds or less, and a processor generating a three-dimensional computed tomography image data set resolving voxels with dimensions of 0.4 mm or less in at least two orthogonal directions.

摘要翻译： 使用X射线锥束计算机断层摄影或锥束数字断层摄影术对患者未压缩感兴趣区域成像的方法包括将有效量的造影剂引入未压缩感兴趣区域的步骤。 使用锥形束计算机断层摄影（CBCT）或锥束数字断层摄影（CBDT）对患者未压缩感兴趣区域成像的系统包括将X射线发射到感兴趣的未压缩区域的X射线源，获取 多个用于CBCT或CBDT数据集的二维投影图像数据，其具有在35毫秒或更短时间内获取的至少一个投影图像，以及处理器生成三维计算机断层摄影图像数据集，其解析尺寸为0.4mm的体素 或至少两个正交方向。

公开(公告)号：US20070269000A1

公开(公告)日：2007-11-22

申请号：US11437076

申请日：2006-05-18

申请人： Larry Partain ,  Stavros Prionas ,  Edward Seppi ,  Robert Sutherland ,  David Humber ,  Hassan Mostafavi ,  Felix Fernando ,  John Boone

发明人： Larry Partain ,  Stavros Prionas ,  Edward Seppi ,  Robert Sutherland ,  David Humber ,  Hassan Mostafavi ,  Felix Fernando ,  John Boone

IPC分类号： A61B6/04

CPC分类号： A61B6/4241 ,  A61B6/032 ,  A61B6/4085 ,  A61B6/482 ,  A61B6/502 ,  A61B6/507

摘要： A method of imaging a patient's uncompressed region of interest using X-ray cone beam computed tomography or cone beam digital tomography comprises the step of introducing an effective amount of a contrast agent to the uncompressed region of interest. A system for imaging a patient's uncompressed region of interest using cone beam computed tomography (CBCT) or cone beam digital tomography (CBDT) comprises an X-ray source transmitting an X-ray to the uncompressed region of interest, an image acquisition system acquiring a plurality of two-dimensional projection images data for a CBCT or CBDT data set with at least one of the projection images acquired in 35 milliseconds or less, and a processor generating a three-dimensional computed tomography image data set resolving voxels with dimensions of 0.4 mm or less in at least two orthogonal directions.

摘要翻译： 使用X射线锥束计算机断层摄影或锥束数字断层摄影术对患者未压缩感兴趣区域成像的方法包括将有效量的造影剂引入未压缩感兴趣区域的步骤。 使用锥形束计算机断层摄影（CBCT）或锥束数字断层摄影（CBDT）对患者未压缩感兴趣区域成像的系统包括将X射线发射到感兴趣的未压缩区域的X射线源，获取 多个用于CBCT或CBDT数据集的二维投影图像数据，其具有在35毫秒或更短时间内获取的至少一个投影图像，以及处理器，其生成尺寸为0.4mm的三维计算机断层摄影图像数据集 或至少两个正交方向。

公开(公告)号：US20050201509A1

公开(公告)日：2005-09-15

申请号：US10801947

申请日：2004-03-15

申请人： Hassan Mostafavi ,  Edward Seppi ,  Larry Partain

发明人： Hassan Mostafavi ,  Edward Seppi ,  Larry Partain

IPC分类号： A61B5/113 ,  A61B6/00 ,  A61B6/03 ,  G01N23/00 ,  G21K1/12 ,  H05G1/60

CPC分类号： A61B6/032 ,  A61B5/1135 ,  A61B5/7289 ,  A61B6/4441 ,  A61B6/541

摘要： A method for collecting computed tomography (CT) image data includes determining a number of intervals N into which a respiratory cycle is to be divided, determining a number of respiratory cycles M to be covered in one gantry rotation, and rotating a gantry to collect at least M×N sets of CT image data of at least a portion of a patient, wherein each set of the CT image data corresponds to a phase of a respiratory cycle.

摘要翻译： 收集计算机断层摄影（CT）图像数据的方法包括确定要分割呼吸周期的间隔N的数量，确定在一台架旋转中要覆盖的呼吸周期M的数量，以及旋转台架以收集 至少一部分患者的至少M×N组CT图像数据组，其中每组CT图像数据对应于呼吸周期的相位。

公开(公告)号：US20050084073A1

公开(公告)日：2005-04-21

申请号：US10687573

申请日：2003-10-15

申请人： Edward Seppi ,  Gary Virshup

发明人： Edward Seppi ,  Gary Virshup

IPC分类号： A61B20060101 ,  G21K3/00 ,  H01J35/10 ,  H01J35/14 ,  H01J35/28 ,  H01J35/30

CPC分类号： H01J35/101 ,  A61B5/7289 ,  A61B5/7292 ,  A61B6/032 ,  A61B6/4035 ,  A61B6/405 ,  A61B6/482 ,  A61B6/502 ,  A61B6/5288 ,  A61B6/541 ,  H01J35/14 ,  H01J35/28 ,  H01J35/305 ,  H01J2235/088 ,  H01J2235/1006

摘要： An apparatus for use in a radiation procedure includes a radiation filter having a first portion and a second portion, the first and the second portions forming a layer for filtering radiation impinging thereon, wherein the first portion is made from a first material having a first x-ray filtering characteristic, and the second portion is made from a second material having a second x-ray filtering characteristic. An apparatus for use in a radiation procedure includes a first target material, a second target material, and an accelerator for accelerating particles towards the first target material and the second target material to generate x-rays at a first energy level and a second energy level, respectively.

摘要翻译： 用于辐射过程的装置包括具有第一部分和第二部分的辐射过滤器，第一和第二部分形成用于过滤辐射的辐射层，其中第一部分由具有第一部分和第二部分的第一材料制成， 射线滤波特性，第二部分由具有第二x射线滤波特性的第二材料制成。 用于辐射过程的装置包括：第一靶材料，第二靶材料和用于将颗粒朝向第一靶材料加速的加速器和第二靶材料，以在第一能级和第二能级产生X射线 ， 分别。

公开(公告)号：US20100080337A1

公开(公告)日：2010-04-01

申请号：US12239699

申请日：2008-09-26

申请人： Edward Seppi ,  Edward Shapiro ,  Gary Virshup ,  Josh Star-Lack

发明人： Edward Seppi ,  Edward Shapiro ,  Gary Virshup ,  Josh Star-Lack

IPC分类号： G21K1/00 ,  H05G1/60

CPC分类号： G21K1/10 ,  A61B6/00 ,  A61B6/4291

摘要： Disclosed are systems, methods, and computer program products that generate estimates of errors caused by extraneous radiation in tomographic systems, such as cone-beam computerized tomography (CBCT) systems, fluoroscopic tomography systems, radiographic tomography systems, laminar tomography imaging systems, and the like. In one group of inventions, spatial errors are estimated from projection data collected where a known spatial perturbation has been introduced into radiation intensity of the source. In another group of inventions, temporal errors are estimated from a sequence of projections where a known perturbation in the radiation intensity of the source for different projections has been introduced.

摘要翻译： 公开了系统，方法和计算机程序产品，其产生在层析成像系统中由外部辐射引起的误差的估计，诸如锥束计算机断层摄影（CBCT）系统，荧光透视断层摄影系统，放射照相层析成像系统，层析成像系统，以及 喜欢。 在一组发明中，空间误差是从收集的投影数据估计的，其中已知的空间扰动已被引入到源的辐射强度。 在另一组发明中，根据已经引入了用于不同投影的源的辐射强度的已知扰动的一系列投影来估计时间误差。

公开(公告)号：US07394889B2

公开(公告)日：2008-07-01

申请号：US11437076

申请日：2006-05-18

申请人： Larry D. Partain ,  Stavros Prionas ,  Edward Seppi ,  Robert Sutherland ,  David Humber ,  Hassan Mostafavi ,  Felix Fernando ,  John Boone

发明人： Larry D. Partain ,  Stavros Prionas ,  Edward Seppi ,  Robert Sutherland ,  David Humber ,  Hassan Mostafavi ,  Felix Fernando ,  John Boone

IPC分类号： A61B6/04

CPC分类号： A61B6/4241 ,  A61B6/032 ,  A61B6/4085 ,  A61B6/482 ,  A61B6/502 ,  A61B6/507

摘要： A method of imaging a patient's uncompressed region of interest using X-ray cone beam computed tomography or cone beam digital tomography comprises the step of introducing an effective amount of a contrast agent to the uncompressed region of interest. A system for imaging a patient's uncompressed region of interest using cone beam computed tomography (CBCT) or cone beam digital tomography (CBDT) comprises an X-ray source transmitting an X-ray to the uncompressed region of interest, an image acquisition system acquiring a plurality of two-dimensional projection images data for a CBCT or CBDT data set with at least one of the projection images acquired in 35 milliseconds or less, and a processor generating a three-dimensional computed tomography image data set resolving voxels with dimensions of 0.4 mm or less in at least two orthogonal directions.

摘要翻译： 使用X射线锥束计算机断层摄影或锥束数字断层摄影术对患者未压缩感兴趣区域成像的方法包括将有效量的造影剂引入未压缩感兴趣区域的步骤。 使用锥形束计算机断层摄影（CBCT）或锥束数字断层摄影（CBDT）对患者未压缩感兴趣区域成像的系统包括将X射线发射到感兴趣的未压缩区域的X射线源，获取 多个用于CBCT或CBDT数据集的二维投影图像数据，其具有在35毫秒或更短时间内获取的至少一个投影图像，以及处理器，其生成尺寸为0.4mm的三维计算机断层摄影图像数据集 或至少两个正交方向。

公开(公告)号：US06907106B1

公开(公告)日：2005-06-14

申请号：US09379439

申请日：1999-08-23

申请人： Raymond D McIntyre ,  Stanley W Johnsen ,  Marcel Marc ,  Michelangelo Delfino ,  Edward Seppi

发明人： Raymond D McIntyre ,  Stanley W Johnsen ,  Marcel Marc ,  Michelangelo Delfino ,  Edward Seppi

IPC分类号： G21G1/12 ,  G21G4/08

CPC分类号： G21G1/12 ,  G21G4/08

摘要： An apparatus and method for irradiating target objects, especially medical stents for in vivo implantation. A linear accelerator provides a high energy electron beam that impinges upon and is received by an x-ray conversion target. The x-ray conversion target is activated by either a static or dynamically moveable electron beam to generate and emit an x-ray flux so as to efficiently intercept the target object. The x-ray flux is directed to the target object for a desired time period and is of sufficiently high energy to efficiently impart radioactive properties to the target object. Alternatively, the target object is positioned within the path of the x-ray flux or is translated within the path during irradiation. Mechanical transport assemblies such as a carousel, rotational and/or linear translator and/or movement tube system also may be provided.

摘要翻译： 用于照射目标物体的装置和方法，特别是用于体内植入的医用支架。 线性加速器提供冲击并由X射线转换目标接收的高能电子束。 X射线转换目标由静态或动态可移动的电子束激活，以产生和发射X射线通量，以有效地拦截目标物体。 x射线通量被引导到目标物体所需的时间段，并且具有足够高的能量以有效地赋予目标物体放射性。 或者，目标物体位于X射线通量的路径内，或者在照射期间在路径内平移。 还可以提供诸如转盘，旋转和/或线性平移器和/或运动管系统之类的机械输送组件。