-
公开(公告)号:US4517289A
公开(公告)日:1985-05-14
申请号:US409183
申请日:1982-08-18
IPC分类号: G01N33/53 , C07K14/005 , C07K14/195 , C07K16/00 , C07K16/28 , C12N15/02 , C12P21/08 , G01N33/577 , G01N33/54 , A61K39/395 , C12N5/00 , C12N15/00 , C12R1/91
CPC分类号: C07K16/2833 , Y10S435/81 , Y10S435/948 , Y10S435/966 , Y10S435/975 , Y10S436/821 , Y10S530/806 , Y10S530/809 , Y10S530/83
摘要: Immortal, antibody-producing, hybridomally-produced clones which produce antibodies that react specifically with human HLA antigens and which are produced from rat lymphocyte cells sensitized against cells from a rat strain having different histocompatibility antigens are disclosed along with methods of producing the clones and antibodies and methods of using the antibodies in tissue crossing tests.
摘要翻译: 公开了产生与人HLA抗原特异性反应的抗体并且由对来自具有不同组织相容性抗原的大鼠菌株的细胞敏感的大鼠淋巴细胞产生的抗体产生的杂交产生的克隆以及产生克隆和抗体的方法 以及在组织交叉试验中使用抗体的方法。