公开(公告)号：US20240189335A1

公开(公告)日：2024-06-13

申请号：US18390347

申请日：2023-12-20

申请人： EMORY UNIVERSITY

发明人： George R. PAINTER ,  Gregory R. BLUEMLING ,  Michael G. NATCHUS ,  David GUTHRIE

IPC分类号： A61K31/7068 ,  A61P31/12 ,  C07H19/067

CPC分类号： A61K31/7068 ,  A61P31/12 ,  C07H19/067

摘要： This disclosure relates to certain N4-hydroxycytidine derivatives, pharmaceutical compositions, and methods related thereto. In certain embodiments, the disclosure relates to the treatment or prophylaxis of viral infections, such as Eastern, Western, and Venezuelan Equine Encephalitis (EEE, WEE and VEE, respectively), Chikungunya fever (CHIK), Ebola, Influenza, RSV, and Zika virus infection with the disclosed compounds.

公开(公告)号：US20200276219A1

公开(公告)日：2020-09-03

申请号：US16755779

申请日：2018-12-07

申请人： EMORY UNIVERSITY

发明人： George R. PAINTER ,  Gregory R. BLUEMLING ,  Michael G. NATCHUS ,  David GUTHRIE

IPC分类号： A61K31/7068 ,  A61P31/12

摘要： This disclosure relates to certain N4-hydroxycytidine derivatives, pharmaceutical compositions, and methods related thereto. In certain embodiments, the disclosure relates to the treatment or prophylaxis of viral infections, such as Eastern, Western, and Venezuelan Equine Encephalitis (EEE, WEE and VEE, respectively), Chikungunya fever (CHIK), Ebola, Influenza, RSV, and Zika virus infection with the disclosed compounds.